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Matthieu Haudiquet

@matthieu-haudiquet.bsky.social
121 followers 127 following 0 posts

Permanent researcher @inserm.fr @pasteur.fr × @institutcurie.bsky.social Studying ancestral immunity: bacterial anti-phage systems → human innate immunity.

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Reposted by Matthieu Haudiquet
Xavier Charpentier @labxc.bsky.social · 07/07/2026
#microsky New preprint from the lab! Widespread immune systems protect bacteria against conjugative plasmids www.biorxiv.org/content/10.6... Kudos to the extremely talented lead author Ludovic Poiré! Key contributions by @francoisrousset.bsky.social and also help from C. Lesterlin/TacC lab. 🧵⬇️
biorxiv.org
Widespread immune systems protect bacteria against conjugative plasmids
Conjugative plasmids are a class of mobile genetic elements capable of efficient transfer between bacterial cells. Although they can introduce beneficial traits such as antibiotic resistance to recipi...
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Reposted by Matthieu Haudiquet
Aude Bernheim @audeber.bsky.social · 22/05/2026
Great piece and cover @science.org about how our field is uncovering the evolutionary and mechanistic connections between bacterial and eukaryotic immunity ! www.science.org/content/article/ancient-wars-between-microbes-gave-us-key-immune-defenses
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Reposted by Matthieu Haudiquet
Tera Levin @teralevin.bsky.social · 04/05/2026
Here's the link to the preprint: www.biorxiv.org/content/10.6... Looking forward to discussing the story with folks at #SISB2026 this week! 🦠
biorxiv.org
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Reposted by Matthieu Haudiquet
Naama Aviram @naamaaviram.bsky.social · 08/05/2026
That's a wrap on three days of incredible science at #SISB2026! Special thanks to @rockefeller.edu for hosting us on their beautiful campus, to our speakers and poster presenters, and most of all to this community that never fails to inspire. Can't wait for #SISB2027 🫶
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Reposted by Matthieu Haudiquet
Aude Bernheim @audeber.bsky.social · 27/11/2025
🧬🛡️How are new immune mechanisms created? We show how Lamassu antiphage system, originated from a DNA-repair complex and evolved into a compact and modular immune machine, wt Dinshaw Patel lab in @pnas.org. 👏 @matthieu-haudiquet.bsky.social, Arpita Chakravarti & all authors! doi.org/10.1073/pnas...
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Reposted by Matthieu Haudiquet
Aude Bernheim @audeber.bsky.social · 17/07/2025
So great to see the work of the lab being brillantly presented at conferences across 🇮🇹🍦🍝, @matthieu-haudiquet.bsky.social on Evolution and Mechanism of Lamassu in FEMS, Milan and Ernest Mordret on LLM for prediction of antiphage systems in GRC Evolutionary Genomics,Tuscany. Check out their work 👇
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Reposted by Matthieu Haudiquet
Eduardo Rocha @epcrocha.bsky.social · 23/07/2025
Here's our new broad review on the extended mobility of plasmids, about all mechanisms driving and limiting their transfer. From conjugation to conduction, phage-plasmids to hitchers, molecular to evolutionary dynamics, ecology to biotech. The state of affairs. 1/9 academic.oup.com/nar/article/...
graphical abstract of the article the extended mobility of plasmids
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Reposted by Matthieu Haudiquet
Aude Bernheim @audeber.bsky.social · 11/04/2025
It was an honor for my lab and myself to host the meeting on the Immune Systems of Bacteria. Such a high from all the incredible science and sharing with scientists from the whole world the greatness of Paris in the spring. Vive la science, et vive Paris!
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Reposted by Matthieu Haudiquet
Institut Pasteur | 130 years of biomedical research @pasteur.fr · 16/01/2025
The Institut Pasteur has decided to leave X (formerly Twitter) to join BlueSky! 🦋 The Institut Pasteur made this decision due to several serious issues observed on the X platform since its acquisition. Join us here to continue advocating for science. www.pasteur.fr/en/home/pres...
pasteur.fr
Institut Pasteur decides to leave X
The Institut Pasteur, a research organization which for more than 130 years has been committed to tackling infectious diseases, sharing knowledge and defending science, has decided to leave X because ...
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Reposted by Matthieu Haudiquet
Aude Bernheim @audeber.bsky.social · 16/12/2024
Out in NAR, AntiDefenseFinder & our "systematic" analysis of inhibitors of antiphage systems wt Bondy-Denomy lab led by @ftesson.bsky.social and E. Huiting. Not so "systematic" as very few known, fun stuff on MGE, antidefense islands and cool phages exaptations! academic.oup.com/nar/advance-...
academic.oup.com
Exploring the diversity of anti-defense systems across prokaryotes, phages and mobile genetic elements
Abstract. The co-evolution of prokaryotes, phages and mobile genetic elements (MGEs) has driven the diversification of defense and anti-defense systems ali
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