iiinova — where your digital self keeps evolving

Masschelein Lab @masscheleinlab.bsky.social · 20/01/2026

Oral abstract submissions are open for Directing Biosynthesis VIII! Themes include • genetics, enzymology & structural biology of natural product biosynthesis • genome & microbiome mining • synthetic biology & metabolic/microbiome engineering • chemical ecology • biocatalysis .... 👉 lnkd.in/eT_6rpBZ

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Masschelein Lab @masscheleinlab.bsky.social · 27/10/2025

Polyunsaturated fatty acid (PUFA) synthase enzymes turn out to be far more versatile than we ever imagined! In our new preprint, we reveal a largely untapped biosynthetic space where they team up with PKSs and NRPSs to create new types of bioactive amphiphilic metabolites. 👉http://bit.ly/4hzUUak

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Charting the biosynthetic landscape of hybrid polyketide-nonribosomal peptide-specialized lipids

Polyunsaturated fatty acid (PUFA) synthase-like enzymes are best known for their role in membrane lipid biosynthesis in marine bacteria, but have also been repurposed for the assembly of specialized l...

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Reposted by Masschelein Lab

VIB Training & Conferences @vibtrainconf.bsky.social · 07/10/2025

Last chance to join the #Microbes25 party. Join us to explore how microbial cell factories, synthetic biology, and microbial engineering are rewriting the rulebook of applied #microbiology. Final registration is 23 Oct, grab your spot before it's gone:https://vibbio.tech/3KyHcIb #VIBConf

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Masschelein Lab @masscheleinlab.bsky.social · 27/06/2025

🚨 Tired of redundant #BiosyntheticGeneCluster hits? 💥 Check out #CAGEcleaner – our new genome-level dereplication pipeline for BGC mining and comparative analysis. Works with cblaster & CAGECAT. Now out in Bioinformatics: bit.ly/3TghJEx 🔗 GitHub: bit.ly/44rNZK9 🙌 Kudos to our PhD student Lucas!

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CAGEcleaner: reducing genomic redundancy in gene cluster mining

AbstractMotivation. Mining homologous biosynthetic gene clusters (BGCs) typically involves searching colocalised genes against large genomic databases. How

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Reposted by Masschelein Lab

VIB-KU Leuven Center for Microbiology @vibmicrobes.bsky.social · 09/05/2025

🥳 Huge congratulations to Prof. Joleen Masschelein (@masscheleinlab.bsky.social, @viblifesciences.bsky.social, @kuleuvenuniversity.bsky.social) for being awarded the 2025 EFMC Academia Prize!

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Masschelein Lab @masscheleinlab.bsky.social · 28/04/2025

The new #antiSMASH v8 paper is out in @narjournal.bsky.social! It was a pleasure helping to improve the detection of bacterial polyyne biosynthetic gene clusters. Happy mining! 🧬🔍

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Reposted by Masschelein Lab

EMT Conference @emergingmicrotech.bsky.social · 05/12/2024

We are so happy to share that the 2nd Emerging Microbial Technologies conference will take place in Gent next 25th April 2025!! This edition is jointly organized by CMET_UGENT and YBSMicrobiology Follow us also on LinkedIn and X @EMT_conference

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Masschelein Lab @masscheleinlab.bsky.social · 14/12/2024

🎄✨ Festive vibes at our annual lab Christmas dinner! Great food and lots of laughter to wrap up a wonderful year of science and teamwork. Here's to more discoveries and collaborations in the year ahead! 🧫🔬

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Masschelein Lab @masscheleinlab.bsky.social · 19/11/2024

Two weeks ago, we had the pleasure to welcome @nadineziemert.bsky.social as a guest speaker at our Microbes & Booze seminar. She gave a very inspiring talk on mining genomes for new antibiotics - thanks for your visit! 💊🍻

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