Reposted by Marzena Marszałek
@marzena-marszalek.bsky.social et al. integrate WGS and RNAseq from 282 wild yeast strains, finding robust signals of nonsense-mediated mRNA decay but no clear evidence of transcriptional adaptation.
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Signatures of nonsense-mediated mRNA decay but no evidence for transcriptional adaptation associated with protein-truncating variants in wild yeast diploids
Abstract. Transcriptional adaptation (TA) is a regulatory process in which loss or disruption of gene function caused by protein-truncating variants (PTVs)