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Mark A Rubin

@marubin1.bsky.social
47 followers 10 following 6 posts

Precision Oncology researcher in Switzerland with special interest in epigenetics and splicing.

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Reposted by Mark A Rubin
DBMR University Bern @dbmr-unibe.bsky.social · 01/07/2026
🎤 What are the insights that the movie #Jaws can be used to improve the grants one writes? 7 rules of grant writing with examples from movies and sports! @marubin1.bsky.social @medfacultyunibe.bsky.social
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Reposted by Mark A Rubin
DBMR University Bern @dbmr-unibe.bsky.social · 23/06/2026
🔬 The #MSCA @mac4me.bsky.social network just wrapped its second consortium meeting & doctoral training! Five days of technical training, research collaboration, PPI, and professional communication. Great to see @marubin1.bsky.social & Marine Cullier contributing!
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Reposted by Mark A Rubin
Journal of Experimental Medicine @jem.org · 28/05/2026
Researchers at Columbia University have identified a gene that drives the development of neuroendocrine prostate cancer, an aggressive form of the disease. 👉 www.eurekalert.org/news-release... See the original study by the Abate-Shen lab @columbiamed.bsky.social 👉 rupress.org/jem/article-...
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Reposted by Mark A Rubin
ESMO - European Society for Medical Oncology @myesmo.bsky.social · 10/02/2026
📣Updated ESMO #ClinicalPracticeGuideline on advanced and metastatic #ProstateCancer: ✅ Substantial advances in castration-sensitive & -resistant prostate cancer ✅ Updated algorithms & recommendations reflecting latest clinical data #ESMOGuidelines Christopher Sweeney 🔗 ow.ly/E4ov50Yc8e2
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Mark A Rubin @marubin1.bsky.social · 07/02/2026
🧬 New preprint out! Dilara Akhoundova and team identify AURKA as a synthetic lethal vulnerability in FANCA-deficient cancers using complementary CRISPR and drug screens. 🔗 doi.org/10.64898/202... #PrecisionOncology #SyntheticLethality #FANCA #AURKA #CancerGenomics
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Reposted by Mark A Rubin
American Association for Cancer Research (AACR) @theaacr.bsky.social · 22/01/2026
Molecular Cancer Research editor Massimo Loda, Franklin W. Huang, Michael C. Haffner, and Irene Paassen discussed "Genomics and Epigenomics" in a plenary session at the AACR Special Conference on Innovations in Prostate Cancer Research and Treatment. #AACRprostate26 @aacrjournals.bsky.social
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Mark A Rubin @marubin1.bsky.social · 20/01/2026
Can we help men with hormone-refractory #ProstateCancer through personalized epigenetic therapy? Our new study using patient-derived organoids reveals a targetable weakness in a WNT-driven subtype. @genentech.bsky.social @medfacultyunibe.bsky.social @unibe.ch @pmbern.bsky.social tinyurl.com/2tkn3hwh
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Reposted by Mark A Rubin
DBMR University Bern @dbmr-unibe.bsky.social · 06/01/2026
New @natmed.nature.com News & Views by @marubin1.bsky.social and Dr. Irene Paassen on why #PrecisionOncology must go beyond genomics. @medfacultyunibe.bsky.social @pmbern.bsky.social tinyurl.com/2zvdvmy6
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Reposted by Mark A Rubin
ESMO - European Society for Medical Oncology @myesmo.bsky.social · 18/12/2025
📣 Updated ESMO #ClinicalPracticeGuideline on local & locoregional #ProstateCancer: ✅New imaging modalities: Improved diagnosis, staging & risk stratification ✅Updated algorithms: less over-Tx & fewer side-effects #Oncology #UroOncology #CancerCare #ESMOGuidelines 🔗 ow.ly/jwA650XLs1q
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Mark A Rubin @marubin1.bsky.social · 14/12/2025
Excited to share new preprint on the minor spliceosome in cancer! Targeting U6atac disrupts DNA repair and sensitizes prostate & breast tumors to radiation, cisplatin and PARP inhibitors—even beyond BRCA-mutant . bit.ly/48RnsI5 #DNARepair #ProstateCancer #BreastCancer #U6atac @theaacr.bsky.social
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Mark A Rubin @marubin1.bsky.social · 27/11/2025
Congrats to Jia and Michael and team. This has been a major effort and we are learning so much about lineage plasticity www.nature.com/articles/s41....
nature.com
NSD2 targeting reverses plasticity and drug resistance in prostate cancer - Nature
Inhibition of the histone methyltransferase NSD2 and the androgen receptor in preclinical models can reverse lineage plasticity to suppress tumour growth and promote cell death in multiple subtypes of...
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Mark A Rubin @marubin1.bsky.social · 15/02/2025
www.nytimes.com/interactive/...
nytimes.com
How Trump’s Medical Research Cuts Would Hit Colleges and Hospitals in Every State
Changes to a key funding formula will reduce research grants at hospitals and universities by billions — and may discourage future research.
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Mark A Rubin @marubin1.bsky.social · 15/02/2025
I Used to Run the N.I.H. Here’s What Worries Me. www.nytimes.com/2025/02/14/o...
nytimes.com
Opinion | American Science is Under Attack
The Trump administration hobbles research and endangers the public health.
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