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Mark Ashe

@markashe.bsky.social
601 followers 169 following 18 posts

Biologist at Manchester Uni interested in translation/ mRNA plus saddo Wolves fan and rubbish wildlife photographer

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Mark Ashe @markashe.bsky.social · 26/02/2026
Mission accomplished in Boat of Garten recently
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Mark Ashe @markashe.bsky.social · 25/07/2025
Just got back after #yeast2025 - exhausted but a great conference with great science and organisation
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Reposted by Mark Ashe
Hilary Ashe @hilaryashe.bsky.social · 16/07/2025
Biblical!
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Mark Ashe @markashe.bsky.social · 02/05/2025
Great RNA/ protein fate seminar yesterday given by Adrien Rousseau from University of Dundee on proteasome assembly mechnnisms
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Mark Ashe @markashe.bsky.social · 17/04/2025
This paper looks amazing! Probably a very very naive question - but why is a polyA polymerase specific for mRNAs encoding secreted proteins? Are these mRNAs particularly prone to deadenylation? www.nature.com/articles/s41...
nature.com
Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines - Nature
Upon intramuscular administration, COVID-19 mRNA vaccines are primarily taken up by macrophages, in which the cellular machinery extends their poly(A) tails, thereby increasing mRNA stability and tran...
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Mark Ashe @markashe.bsky.social · 01/02/2025
Saw this beauty in Daisy Nook park today
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Mark Ashe @markashe.bsky.social · 14/01/2025
Cool review - very nicely written!!- Fits well with our random thoughts on the connections between RBPs and the glycolysis/ respiration metabolic transition in yeast.
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Mark Ashe @markashe.bsky.social · 19/12/2024
Mixed emotions when a key member of the group moves to pastures new- Good luck in the NZ adventure Rob!!
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Mark Ashe @markashe.bsky.social · 19/12/2024
Anyone fancy doing a phd on oxidative modification of mRNA? Pari is just starting her lab and she’s dedicated, intelligent and lovely to work with- honest!! www.findaphd.com/phds/project...
findaphd.com
BBSRC NWD: Exploitation of RNA modification for optimal protein expression under stress conditions at University of Liverpool on FindAPhD.com
PhD Project - BBSRC NWD: Exploitation of RNA modification for optimal protein expression under stress conditions at University of Liverpool, listed on FindAPhD.com
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Mark Ashe @markashe.bsky.social · 12/12/2024
Interesting paper! www.nature.com/articles/s41...
nature.com
The mechanism of mRNA cap recognition - Nature
Allosteric communication between the eIF4F subunits drives mRNA cap-recognition and subsequent activation of the message.
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Mark Ashe @markashe.bsky.social · 03/12/2024
Oh joy! I’ve been tinselled
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Mark Ashe @markashe.bsky.social · 30/11/2024
Great idea! - also could be adapted for purifying the target RNA with much less background
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Mark Ashe @markashe.bsky.social · 28/11/2024
Wow - how cool is this!!!
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Mark Ashe @markashe.bsky.social · 06/11/2024
Much excitement in chez Ashe - we had a visitor last night! Urban badgers who knew!!
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