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Margo Le

@margole.bsky.social
36 followers 44 following 13 posts

UCSB PhD candidate in Neuroscience and Behavior 🧠 (she/her) KeiflinLab.com

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Margo Le @margole.bsky.social · 04/09/2026
At test, reward-predictive cues biased rule selection, promoting the rule associated with the predicted outcome. Silencing the orbitofrontal-to-secondary motor pathway disrupted this cue-guided *rule* selection. Critically the same manipulation spared cue-evoked *action* selection in PIT paradigm.
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Margo Le @margole.bsky.social · 04/09/2026
To bring this higher-order level of behavioral organization into the lab, we adapted the iconic Pavlovian-to-Instrumental Transfer (PIT) paradigm and developed the Pavlovian-to-Rules-to-Instrumental Transfer (sPRInT).
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Margo Le @margole.bsky.social · 04/09/2026
At test, reward-predictive cues biased rule selection, promoting the rule associated with the predicted outcome. Silencing the orbitofrontal-to-secondary motor pathway disrupted this cue-guided *rule* selection. Critically the same manipulation spared cue-evoked *action* selection in PIT paradigm.
100
Margo Le @margole.bsky.social · 04/09/2026
To bring this higher-order level of behavioral organization into the lab, we adapted the iconic Pavlovian-to-Instrumental Transfer (PIT) paradigm and developed the Pavlovian-to-Rules-to-Instrumental Transfer (sPRInT).
100