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Maartje Westhoff

@maartjewesthoff.bsky.social
25 followers 48 following 0 posts

Postdoc in the Dixon lab at UCDavis. Studying cardiovascular physiology by using advanced imaging techniques and electrophysiology.

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Reposted by Maartje Westhoff
UC Davis Physiology @ucd-physiology.bsky.social · 14/04/2026
Compelling new study by @maartjewesthoff.bsky.social, Taylor Voelker, @roseedixon.bsky.social et al. This latest work in Circulation Research explores what happens when angiotensin II signaling becomes chronic. www.ahajournals.org/doi/10.1161/...
ahajournals.org
Phosphoinositide Depletion and Compensatory Phospho-Signaling in Angiotensin II-Induced Heart Disease: Protection Through PTEN Inhibition | Circulation Research
BACKGROUND: Contractile dysfunction, hypertrophy, and cell death during heart failure are linked to altered Ca2+ handling and elevated levels of the hormone AngII (angiotensin II), which signals throu...
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Reposted by Maartje Westhoff
Rose Dixon @roseedixon.bsky.social · 29/01/2025
New in @pnas.org: We uncovered that the small protein 14-3-3 acts as critical modulatory protein, orchestrating calcium channel trafficking, and fine-tuning the heart's response to stress signals. @ucdavishealth.bsky.social @ucd-physiology.bsky.social @mcipucd.bsky.social pnas.org/doi/full/10....
pnas.org
14-3-3 promotes sarcolemmal expression of cardiac CaV1.2 and nucleates isoproterenol-triggered channel superclustering | PNAS
The L-type Ca2+ channel (CaV1.2) is essential for cardiac excitation–contraction coupling. To contribute to the inward Ca2+ flux that drives Ca2+-i...
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