Reposted by Maartje Westhoff
Compelling new study by @maartjewesthoff.bsky.social, Taylor Voelker, @roseedixon.bsky.social et al. This latest work in Circulation Research explores what happens when angiotensin II signaling becomes chronic. www.ahajournals.org/doi/10.1161/...
ahajournals.org
Phosphoinositide Depletion and Compensatory Phospho-Signaling in Angiotensin II-Induced Heart Disease: Protection Through PTEN Inhibition | Circulation Research
BACKGROUND: Contractile dysfunction, hypertrophy, and cell death during heart failure are linked
to altered Ca2+ handling and elevated levels of the hormone AngII (angiotensin II), which signals
throu...