Loan Vulliard @lvulliard.bsky.social · 28/09/2026Check this out for a flexible framework to go from cell-level measurements to interpretable tissue-level descriptors! 000
Loan Vulliard @lvulliard.bsky.social · 04/08/2026Thanks to @helloeacr.bsky.social for allowing me to attend their annual congress, last June in Budapest. It was a great opportunity to (re-)connect with colleagues, get a broader sense of where cancers therapies are heading, and remember what's exciting about being a scientist! tinyurl.com/2upz6p5umagazine.eacr.orgEACR 2026 Congress Travel Grant recipients share their experiences - The Cancer ResearcherWe met in Budapest, Hungary for the most recent EACR Congress, and were delighted to award several Travel Grants to help cancer researchers in need of financial assistance to attend. 021
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 12/03/2026🧵 See 👇 our new preprint on shared and organ-specific gene expression programs of fibrotic diseases 🧬 📄 Paper: doi.org/10.64898/202... 📊 Explore the data: organfibrosis.saezlab.org 22411
Reposted by Loan VulliardBeth Cimini 🔬💻📊 @bethcimini.bsky.social · 24/11/2025Was lovely to see many of you @ I2K! Despite having major FOMO about missing so much stuff this fall (GloBIAS! CytoData! FoundingGIDE! CBIAS!), conferences ARE usually a great way to find @erinweisbart.bsky.social and I. In Episode 19, we talk through great societies/meetings we think you'll enjoy!youtu.beConferences We've Attended Recently - AskErinDearBeth Episode 19YouTube video by Ask Erin, Dear Beth 094
Reposted by Loan VulliardAlex Kalinin @alxndrkalinin.bsky.social · 31/10/2025Today is the last chance to register for #CytoData2025. Don’t miss a fantastic program covering the full spectrum of image-based profiling! cytodata25.eu-openscreen.eucytodata25.eu-openscreen.euCytodata 032
Reposted by Loan VulliardAndre Rendeiro @andre-rendeiro.com · 15/10/2025New work from Iva Buljan @ivabuljan.bsky.social in our lab! We mapped how human tissue architecture changes with age using ~25k histology slides from 983 donors. This is the first body-wide atlas of human microanatomy. 📄 Preprint: www.biorxiv.org/content/10.1... 1125
Loan Vulliard @lvulliard.bsky.social · 08/10/2025🧭 Colorectal cancer doesn’t follow a single path. Using spatial proteomics on ~500 tumors, we found distinct trajectories from early to late stage, involving the whole tumor microenvironment and its metabolic state. 📄 Preprint: arxiv.org/abs/2510.05083 #SpatialBiology #CRC #ImageBasedProfiling 1/5arxiv.orgRobust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal adenocarcinomasColorectal cancer (CRC) is highly heterogeneous, with five-year survival rates dropping from $\sim$90% in localized disease to $\sim$15% with distant metastases. Disease progression is shaped not only... 183
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 25/08/2025We present our MetaProViz #Rpackage for #metabolomics analysis & prior knowledge integration to generate mechanistic hypotheses on how metabolic changes affect metabolite classes, pathways & environment interaction 🔗 www.biorxiv.org/content/10.1... 📦 saezlab.github.io/MetaProViz/ 🧵 Thread ⬇️ 22613
Reposted by Loan VulliardJess Ewald @ewaldlab.org · 07/08/2025Check out this opportunity to join my lab as a postdoc! www.ebi.ac.uk/research/pos... Every year, faculty from EMBL-EBI and the Wellcome Sanger Institute co-develop projects that allow fellows to be part of ✨both✨ of these amazing research institutes.ebi.ac.ukEMBL-EBI-Sanger postdoctoral fellowships (ESPOD)The ESPOD fellowship builds on the collaborative relationship between EMBL-EBI and the Wellcome Sanger Institute, offering projects that combine experimental (wet-lab) and computational (dry-lab) appr... 31114
Reposted by Loan VulliardMartin Garrido-Rodriguez @martingarridorc.bsky.social · 24/07/2025This project has been in the making for quite some time. CORNETO not only integrates key concepts and methodologies in biological network inference, but also introduces a novel framework for multi-condition analysis. Congrats to the team, and especially to @pablormier.bsky.social for leading this. 073
Reposted by Loan Vulliardcytodata.bsky.social @cytodata.bsky.social · 21/07/2025𝗢𝗻𝗲 𝗪𝗲𝗲𝗸 𝗟𝗲𝗳𝘁: Abstract submission for oral presentations 🗣️ and hackathon registration 🧑💻 for CytoData 2025 Berlin close July 25! Submit abstracts or register here: 🔗 cytodata25.eu-openscreen.eu/registration/ #Cytodata2025 #Hackathon #ImageBasedProfiling 032
Reposted by Loan VulliardAlex Kalinin @alxndrkalinin.bsky.social · 08/07/2025🔬API-first feature extraction for image-based profiling workflows If you need to obtain interpretable features from your segmented microscopy images, but want to do it in a fully automated way, we know the struggle. 1/6 14620
Reposted by Loan Vulliardcytodata.bsky.social @cytodata.bsky.social · 02/07/2025Exciting news! We've extended the deadline for oral submissions for Cytodata 2025. You now have until July 25 to submit oral presentations and register for the hackathon. Don't miss this chance! Poster submission closes September 10, and general registration ends October 1 042
Reposted by Loan Vulliardcytodata.bsky.social @cytodata.bsky.social · 20/06/2025🌟 𝗥𝗲𝗺𝗶𝗻𝗱𝗲𝗿 🌟 The deadline for abstract submissions for oral presentations at Cytodata 2025 in Berlin is approaching! 👉 𝗦𝘂𝗯𝗺𝗶𝘁 𝘆𝗼𝘂𝗿 𝗮𝗯𝘀𝘁𝗿𝗮𝗰𝘁 𝗯𝘆 𝗝𝘂𝗻𝗲 25! cytodata25.eu-openscreen.eu/registration/ #BerlinConference #Imageanalysis #Microscopy 064
Reposted by Loan Vulliardcytodata.bsky.social @cytodata.bsky.social · 23/04/2025Join us in Berlin for CytoData 2025! 👉 Info & registration: cytodata25.eu-openscreen.eu 🔬 Hackathon: Nov 17–19 📢 Symposium: Nov 20–21 Explore advancements in image-based profiling & high-content screening and Tackle real-world challenges using EU-OPENSCREEN data. 042
Reposted by Loan VulliardAndre Rendeiro @andre-rendeiro.com · 12/06/2025🚨 3 days left to apply! Join us at CeMM (Vienna) to work on AI + computational pathology projects like LazySlide. Amazing team, H100 GPUs, real impact. Apply now: cemm.at/join-cemm/op...cemm.atOpen PositionsCeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences 011
Loan Vulliard @lvulliard.bsky.social · 11/06/2025If you need to compare profiles across many conditions or perturbations, have a look! 010
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 23/05/2025Ever wondered which method to use to infer kinase activities from phosphoproteomics data? 💻💭Our revised comprehensive evaluation of kinase activity inference tools, done in collaboration with the Zhang lab @bcmhouston.bsky.social, is now out @natcomms.nature.com 🔬 tinyurl.com/4twuc6z4 14720
Reposted by Loan VulliardSalvo Danilo Lombardo @salvod-lombardo.bsky.social · 09/05/2025Have you ever wondered how protein interactions change across tissues and over time? #networkmedicine #development #aging 👇 Check what we found under the incredible mentorship of #menchelab & @andre-rendeiro.com : www.biorxiv.org/content/10.1...biorxiv.orgA multilayer network approach elucidates time- and tissue-specific developmental and aging processesUnderstanding the dynamic interplay of proteins across different life stages and tissues is essential for deciphering the molecular mechanisms underpinning development, aging, and disease. Here, we pr... 711
Loan Vulliard @lvulliard.bsky.social · 07/05/2025If you're interested in finding recurrent spatial patterns in your tissues, now is a good time to check out Kasumi! 030
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 22/04/2025We have an opening for a PhD/Postdoc in Spatial Omics for Cardiology in Heidelberg 🫀 #job #academicjob #phd #postdoc #cadiology 👇 jobrxiv.org/job/heidelbe...jobrxiv.orgPhD/Postdoc in Spatial Omics for CardiologyPost a job in 3min, or find thousands of job offers like this one at jobRxiv! 068
Loan Vulliard @lvulliard.bsky.social · 23/04/2025Registrations are open for the best scientific event of the year! Source: my very unbiased and authoritative opinion 😂 Join us in Berlin in November to discuss the best ways to go from images to biological insight and new treatments. 020
Reposted by Loan VulliardJovan Tanevski @tanevski.bsky.social · 22/04/2025🚨 New preprint: Topography Aware Optimal Transport for Alignment of Spatial Omics Data We present our new alignment framework TOAST www.biorxiv.org/content/10.1... 13117
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 09/04/2025Congrats & Good luck to our @slobentanzer.bsky.social as he starts his group @diabresearch-dzd.bsky.social & @comphealthmunich.bsky.social - he is hiring 👇 0138
Reposted by Loan VulliardChris Fell @cfell.bsky.social · 09/04/2025So excited to share our new paper out today in @nature.com. We repurposed R2 retrotransposons to create STITCHR, a tool that can make virtually any kind of edit in mammalian genomes including the scarless multi-kilobase scale insertions 🧵 www.nature.com/articles/s41...nature.comReprogramming site-specific retrotransposon activity to new DNA sites - NatureA study of retrotransposon activity repurposes a retroelement called R2Tocc to create a programmable system called STITCHR that enables diverse genome edits including efficient, scarless large pa... 33110
Loan Vulliard @lvulliard.bsky.social · 09/04/2025Interested in supporting the advancement of image-based profiling? Want to shape how large cell and tissue image datasets will be analyzed in the future? Please consider hosting CytoData! 010
Reposted by Loan VulliardBeth Cimini 🔬💻📊 @bethcimini.bsky.social · 07/04/2025Delighted to announce that @erinweisbart.bsky.social and I have teamed up to create a new bioimage analysis video podcast called Ask Erin/Dear Beth - you can check it out at the link below! It will highlight common challenges in #bioimageanalysis, as well as our favorite solutions to them. (1/x)youtube.comAsk Erin, Dear BethOn Ask Erin/Dear Beth, bioimage analysis experts Beth Cimini and Erin Weisbart, of the Imaging Platform at the Broad Institute of MIT and Harvard, answer your image analysis questions! Whether it’s ab... 15630
Loan Vulliard @lvulliard.bsky.social · 31/03/2025Big news, you can now follow the CytoData society on BS and get even more image-based profiling in your timeline 🤓 010
Reposted by Loan VulliardLeeat Keren @leeat-keren.bsky.social · 26/03/2025Super excited to finally see this published! Our new method to use combinatorial staining and deep learning to push the multiplexing boundaries of spatial proteomics! 43017
Reposted by Loan VulliardGalaxy Project @galaxyproject.bsky.social · 17/03/2025The GBCC2025 Scholarships are here! Thanks to the JXTX Foundation and Galaxy Project, 4 genomics and data science graduate students will receive scholarships to attend GBCC2025 in person. 📅 Apply by April 1, 2025 👉 jxtxfoundation.org/news/2025-2-...jxtxfoundation.orgJXTX + GBCC 2025 ScholarshipsJXTX + GBCC 2025 Scholarships 013
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 20/02/2025The first version of NetworkCommons is now published in Bioinformatics. Next, we’ll focus on involving more of the network biology community. academic.oup.com/bioinformati... In parallel, we’ll continue expanding benchmarks and developing new applications. Interested in contributing? Reach out! ⬇️academic.oup.comNetworkCommons: bridging data, knowledge and methods to build and evaluate context-specific biological networksAbstractSummary. We present NetworkCommons, a platform for integrating prior knowledge, omics data, and network inference methods, facilitating their usage 04420
Reposted by Loan VulliardJulio Saez-Rodriguez @juliosaezrod.bsky.social · 11/02/2025Post-doc opening to join our lab @ebi.embl.org to develop&apply #bioinformatics and #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data - please share 🙏 : embl.wd103.myworkdayjobs.com/EMBL/job/Hin...embl.wd103.myworkdayjobs.comPostdoctoral fellow - Saez-Rodriguez GroupYour group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools... 05846
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 05/02/2025Applying LLMs to biomedical research today can go one of two ways: we either use a closed-source web app, or we get coding ourselves. Many researchers lack training for the latter, so their only choice is the former. We want to change that. www.nature.com/articles/s41... 27837
Reposted by Loan VulliardPeter Murphy @peterwmurphy1.bsky.social · 01/01/2025For Maths fans, 2025 is a square. 45² = 45 x 45 = 2025 Also, 9² x 5² = 2025 40² + 20² + 5² = 2025 My favourite? 1³+2³+3³+4³+5³+6³+7³+8³+9³ = 2025 #Mathematics #teaching #education 916248284694
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 23/12/2024We present Gene Regulatory nETwork Analsyis (GRETA), a framework to infer, compare and evaluate gene regulatory networks #GRNs. With it, we have benchmarked multimodal and unimodal GRN inference methods. Check the results here 👇 Paper: doi.org/10.1101/2024.12.20.629764 Code: github.com/saezlab/greta 112746
Reposted by Loan VulliardRita Strack @ritastrack.bsky.social · 06/12/2024I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...nature.comMethod of the Year 2024: spatial proteomics - Nature MethodsApproaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease. 3614170
Reposted by Loan VulliardFerris Jabr @ferrisjabr.bsky.social · 27/11/2024I was deeply disappointed by the lack of nature/science/climate/enviro on many major end-of-year book lists—so I decided to make my own! Introducing: ✨🎁📚 The 2024 Holiday Gift Guide to Nature & Science Books ✨🎁📚 Please share: Let's make this go viral in time for Black Friday / holiday shopping! 35394172638
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 26/11/2024We present NetworkCommons, a unified platform 🪐 for network biology, providing access to omics data, knowledge, and contextualization methods, all with a consistent API 👇🧵 Paper: doi.org/10.1101/2024... Docs: networkcommons.readthedocs.io 29632
Loan Vulliard @lvulliard.bsky.social · 20/11/2024One full year to get ready: join us next year in Berlin-Buch if you're into spatial biology, morphology and/or high-content perturbation screens! 🔬💻 #CytoData #Microscopy #ImageBasedProfiling 1209
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 11/11/2024Hi 🦋 This is the saezlab (saezlab.org) bluesky account. We integrate #omics data with mechanistic molecular knowledge into statistical and machine learning #ML methods, and we share our tools as free #opensource packages (github.com/saezlab/) #systemsbiology #biology #compbiosaezlab.orgSaez-Rodriguez GroupSaez-Rodriguez Group – Systems Biomedicine 05518
Reposted by Loan VulliardAndre Rendeiro @andre-rendeiro.com · 16/11/2024What if we could look at a human tissue image🔬and quantify its biological age?🧬 And how could we get the same insights without collecting the tissue sample? In our new @biorxivpreprint, we create "tissue clocks" ⏳to do just that! www.biorxiv.org/content/10.1... 📝 #aging #tissue thread below⬇️ 23713
Reposted by Loan VulliardSaez-Rodriguez Group @saezlab.bsky.social · 11/11/2024What are the key disrupted multicellular processes in heart failure? In our new work we combine 23 years of molecular data with recent single-cell atlases to draw a cross-study patient map doi.org/10.1101/2024... 02610