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Leeat Keren

@leeat-keren.bsky.social
356 followers 134 following 41 posts

Assistant Prof. at Weizmann Institute of Science. Spatial Proteomics, Immunology, Cancer, Imaging, CompBio.

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Leeat Keren @leeat-keren.bsky.social · 31/07/2026
So excited to see this out! CellTune, our software for cell classification in Spatial Proteomics, is published in Nature Methods www.nature.com/articles/s41...
nature.com
CellTune: an integrative software for accurate cell classification in spatial proteomics - Nature Methods
CellTune enables high precision analysis of spatial proteomics datasets through a human-in-the-loop active learning workflow.
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Leeat Keren @leeat-keren.bsky.social · 06/11/2025
Paper alert! A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology. We examined how immune cells are organized in the gut and what happens to them in GVHD. TL;DR Timing is key! www.science.org/doi/10.1126/...
science.org
A spatial atlas of human gastrointestinal acute GVHD reveals epithelial and immune dynamics underlying disease pathophysiology
Multiplexed imaging of aGVHD GI biopsies revealed epithelial remodeling and alteration in immune composition, offering insight into disease pathology.
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Leeat Keren @leeat-keren.bsky.social · 15/05/2025
🚨Preprint Alert!🚨 Cell classification is one of the most difficult tasks in analyzing spatial data. We present CellTune - a powerful toolkit for accelerating biological discovery in spatial proteomics. 📄 www.biorxiv.org/content/10.1... 👇🧵1/7
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Leeat Keren @leeat-keren.bsky.social · 15/05/2025
If I were a student - I would definitely join 🤩 Best PI and super cool science.
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Leeat Keren @leeat-keren.bsky.social · 26/03/2025
Super excited to finally see this published! Our new method to use combinatorial staining and deep learning to push the multiplexing boundaries of spatial proteomics!
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Leeat Keren @leeat-keren.bsky.social · 10/03/2025
@yardenasamuels.bsky.social opening #MICC2025 in Athens - the birthplace of Democracy. Looking forward to an amazing conference!
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Leeat Keren @leeat-keren.bsky.social · 27/11/2024
Preprint alert! We profiled immune organization in sentinel lymph nodes (sLNs) of melanoma patients using spatial proteomics and spatial transcriptomics, and found that it is prognostic of distant metastases. biorxiv.org/cgi/content/...
biorxiv.org
Immune organization in sentinel lymph nodes of melanoma patients is prognostic of distant metastases
Sentinel lymph node (sLN) biopsy is part of melanoma staging, as involved LNs indicate a higher risk of recurrence. However, how the sLN is shaped by the tumor and reciprocally affects metastatic prog...
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