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Sam

@llssam.bsky.social

27 followers 99 following 0 posts

Lattice lightsheet enthusiast, lager-enjoyer Postdoc in Culley Group at King’s College London she/her

Posts Replies Media

Reposted by Sam

Siân Culley @superresolusian.bsky.social · 07/08/2025

Hello! Very excited to share our latest preprint, which is great news for us but terrible news for any diehard fans of PSNR and SSIM as image quality metrics in microscopy... (1/5) www.biorxiv.org/content/10.1...

biorxiv.org

Image quality metrics fail to accurately represent biological information in fluorescence microscopy

Image processing methods offer the potential to improve the quality of fluorescence microscopy data, allowing for image acquisition at lower, less phototoxic illumination doses. The training and evalu...

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Reposted by Sam

Journal of Cell Science @jcellsci.bsky.social · 07/08/2025

In their Opinion article, Samantha Webster @llssam.bsky.social, Remi Brynn and Kate Poole @katepoole.bsky.social consider how perspectives from both cell biologists and biophysicists will be crucial for characterising mechanosensitive ion channels in vivo. journals.biologists.com/jcs/article/...

Examples of in vitro measurements (left panel) and the in vivo mechanical landscapes where tissues and cells experience complex compound forces (right panel). In vitro experimental techniques can provide detailed information about specific properties of mechanosensitive ion channels. However, an experimental gap remains in understanding how channels are activated and the consequences of their function in complex in vivo settings.

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