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Lizebona August

@lizebonaaugust.bsky.social

Mechanobiology → organellar mechanotransduction via high-frequency acoustics (MHz). Mitochondria (POLG), RNA & Cajal bodies → cancer plasticity. Toward regenerative & exosome therapeutics.

Posts Replies Media

Lizebona August @lizebonaaugust.bsky.social · 05/03/2026

Congratulations, @carmeloferrai.bsky.social and team, on this exciting study! Really interesting work linking nanotopographical sensing, nuclear mechanoresponse, and KDM3A-dependent chromatin regulation in mESCs — a beautiful example of how physical cues can translate into epigenetic control.

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Lizebona August @lizebonaaugust.bsky.social · 04/10/2025

Now online! 🎉 The article @carmeloferrai.bsky.social announced as accepted is out in Advanced Science: advanced.onlinelibrary.wiley.com/doi/10.1002/... Part of our series on how sound directs cell fate — the foundation of #sonomechanobiology 🎶🔬 Grateful to Carmelo, Leslie & Blanca 🙏

advanced.onlinelibrary.wiley.com

Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells

Brief 10 min bursts of high frequency (10 MHz) vibrational mechanostimulation to stem cells are shown to activate their epigenetic machinery to condition their differentiation down an osteogenic line...

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