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Lisa Watt

@lisawatt.bsky.social
20 followers 41 following 0 posts

PhD student @ EPFL 🇨🇭 in the Gräff lab 🧠🐁🧬 Epigenetics - Neuroscience - Memory

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Reposted by Lisa Watt
Davide Martino Coda @dmcoda.bsky.social · 03/11/2025
🚨 @lisawatt.bsky.social 's paper is out! We uncovered an epigenetic ‘swing’ that tunes how neuronal ensembles capture memories in the brain 🧬🛝🧠. A project that I co-supervised with @graeffjohannes.bsky.social. Kudos to all authors! onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com
Manipulating Engram Histone Acetylation Alters Memory Consolidation
The epigenome provides the brain with a nucleus-templated form of plasticity that is of fundamental importance for learning and memory. Of the various types of epigenetic modifications, elevations in....
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Reposted by Lisa Watt
Davide Martino Coda @dmcoda.bsky.social · 29/10/2025
🚨The paper from my postdoc in @graeffjohannes.bsky.social’s lab at @epfl-brainmind.bsky.social is out! We show that memories can be switched on and off by simply changing the « packaging » of DNA in neurons through epigenetic editing. www.nature.com/articles/s41...
nature.com
Cell-type- and locus-specific epigenetic editing of memory expression - Nature Genetics
CRISPR-based epigenetic editing is used in a cell-type-specific, locus-restricted and temporally controllable manner in the adult mouse brain to modulate memory expression.
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