LernerLab @lernerlab.bsky.social · 02/08/2026We had a farewell party for Yair Razvag. Yair joined us from the very beginning. Among many contributions, he led the dev. of FRETsael microscopy (doi.org/10.1016/j.bp...). Yair has decided to continue in a different direction and refreshing new start. Yair, you will be missed by all lab members. 000
LernerLab @lernerlab.bsky.social · 06/05/2026I'd like to thank my team members for this printed present. 040
LernerLab @lernerlab.bsky.social · 29/04/2026www.biorxiv.org/content/10.6... Single-molecule fluorescence bursts of FP-tagged proteins are achieved in live cells using a new method, BLISS, exposing a rare subpopulation of heterochromatin protein 1alpha dense clusters in undifferentiated embryonic stem cells.biorxiv.org 120
LernerLab @lernerlab.bsky.social · 25/12/2025I wish all my friends and colleagues worldwide a Merry Xmas and a happy and fruitful new year 010
LernerLab @lernerlab.bsky.social · 21/10/2025Open post-doctoral research position in my laboratory at the Hebrew University of Jerusalem. Details in the attached ad. If you are interested, please send your CV, cover letter, and list of references here or to Eitan.Lerner@mail.huji.ac.il 030
LernerLab @lernerlab.bsky.social · 25/09/2025What a fantastic workshop it was, celebrating 30 years to @picoquant.bsky.social Thanks for assisting establishing and maintaining the single molecule spectroscopy community, and for many more years. Thanks also for the chance to give a talk about iur recent photosynthesis-related work. 020
LernerLab @lernerlab.bsky.social · 21/07/2025Khalil Joron, a very talented PhD student from my group, has won the prestigious 2025 #Clore fund #Scholarship for outstanding doctoral students. Khalil develops fluorescence-based tools for sensing microenvironmental properties of phase-separated bio-condensates. Big congrats, Khalil. 020
LernerLab @lernerlab.bsky.social · 10/06/2025PDRA in molecular etiology of Parkinson's disease. We seek to characterize biomolecular species inducing disease-promoting cellular toxicity. Research involves single-molecule assays, advanced fluorescence imaging, mass-spectrometry and structural modeling Apply for funding - Fullbright fellowship 010
LernerLab @lernerlab.bsky.social · 05/06/2025Congratulate Paz Drori from my group, for being awarded the Alexander Silberman Institute's SMART prize for her work on developing the flow virometer approach (summarized in this paper: doi.org/10.1016/j.is...). 020
LernerLab @lernerlab.bsky.social · 14/04/2025doi.org/10.1038/s435... which established a specific tRNA fragment (tRF) motif as target in blood testing for pre-symptomatic Parkinson's disease. Our contribution: showing translational inhibition via disrupted ribosomal association of the tRF. Thanks, Hermona Soreq and team.doi.orgPre-symptomatic Parkinson’s disease blood test quantifying repetitive sequence motifs in transfer RNA fragments - Nature AgingMadrer et al. identify a Parkinson’s disease–specific increase in transfer RNA (tRNA) fragments in human blood, cerebrospinal fluid and postmortem brain tissue, demonstrating the ability of blood-base... 030
Reposted by LernerLabMetaphor Man @metaphorman.bsky.social · 13/04/2025“This discovery represents a major advancement in our understanding of Parkinson’s disease and offers a simple, minimally invasive blood test as a tool for early diagnosis,” said Prof Hermona Soreq of the Hebrew University of Jerusalem, who supervised the study" www.theguardian.com/society/2025...theguardian.comBlood test could detect Parkinson’s disease before symptoms emergeResearchers behind test using biomarkers say it could ‘revolutionise’ early diagnosis of disease 001
Reposted by LernerLabBiophysical Chemistry @bpc-tudo.bsky.social · 17/03/2025Congrats Gabriel, the team and our collaborators from Hebrew U on two new papers on compact microscopes (www.science.org/doi/full/10....) and their applications to virus detection (www.cell.com/iscience/ful... - we got even featured in Nature: www.nature.com/articles/d41....nature.comA ‘Swiss army knife’ microscope that doesn’t break the bankThe parts of a 3D-printed device can be changed out, allowing for versatility as well as ultrahigh resolution. 0102
LernerLab @lernerlab.bsky.social · 05/03/2025Are you looking for a postdoc position and in search of appropriate funding? Check this opportunity out this opportunity (azrielifoundation.org/azrieli-fell...) and discuss with me the opportunity for a postdoctoral research position in my lab and the several leading-edge projectsazrielifoundation.orgCall for Applications for the Azrieli International Postdoctoral Fellowship - The Azrieli Foundation 100
LernerLab @lernerlab.bsky.social · 28/02/2025Thanks, @sarahrauscher.bsky.social lab. It was an honor to contribute to this work. PEG is not a typical crowder. Even highly stable proteins, e.g., mCherry, undergo specific interactions with PEG that above a given concentration will seemingly induce phase separation of this well-folded protein. 141
LernerLab @lernerlab.bsky.social · 11/02/2025It is almost happening - #BPS2025 - and we are happy to attend and present our research. A thread. 1) I will give a talk on Saturday morning at the Biological Fluorescence subgroup, presenting the work spearheaded by the PhD student Khalil Joron, about 1102
Reposted by LernerLabGal Haimovich ☣ 🧪🔬🎗 @grnfluoresceblg.bsky.social · 22/01/2025Dear US Scientists friends, I feel for you. Just be prepared - it'll probably get worse. How do I know? because academia in Israel is also fighting a fascist gov. Thankfully, they're an incompetent bunch and still don't have so much power as POTUS... But we've already seen attempts to pass laws >> 251
Reposted by LernerLabJoachim Goedhart @joachimgoedhart.bsky.social · 25/11/2024The dark side of fluorescent protein tagging: the impact of protein tags on biomolecular condensation www.biorxiv.org/content/10.1... 10305119
LernerLab @lernerlab.bsky.social · 13/11/2024Perhaps, as initial post, I'll reiterate this work, where we use the fact that in photosynthetic unicellular species, autofluorescence is rich in meaningful multiparameter data. This work was first in several upcoming works, stepping into complexities of photosynthesis doi.org/10.1111/febs...doi.orgFEBS PressPhytoplankton cells of the same species in the same environment exhibit cell-wide coordination into distinct subpopulations of photophysiological cell states. Upon a rapid change in light intensity, .... 010
Reposted by LernerLabJohannes Hohlbein @hohlbeinlab.bsky.social · 13/11/2024First attempt in a (loosely defined) Single-Molecule Biophysics starter pack. Please share and (self-) nominate. go.bsky.app/CteFZM5 6510760
LernerLab @lernerlab.bsky.social · 13/11/2024Hello World, and everyone here. After a long time spent in other social media networks, with the rise of non-scientific content slowly creeping in, until its recent spiking, I decided to move to BlueSky, with the hope that my lab/team will find the strictly-scientific safe haven. Fingers crossed. 080