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Leann Tilley

@leanntilley.bsky.social
215 followers 74 following 144 posts

@LeannTilley Biochemist. Biophysicist. Malaria scientist. Leann thinks solving malaria will require collaborative interactions across academia and industry.

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Reposted by Leann Tilley
Cell Press @cellpress.bsky.social · 15/04/2026
"Reaction hijacking of enzymes to generate potent therapeutic modulators in situ" spkl.io/63328A2hIp @leanntilley.bsky.social & colleagues @cp-trendsbiochem.bsky.social
first page of review "Reaction hijacking of enzymes to generate potent therapeutic modulators in situ"
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Leann Tilley @leanntilley.bsky.social · 20/04/2026
Can enzymes be made to self-destruct for therapeutic purposes? “Reaction-hijacking of enzymes to generate potent therapeutic modulators in situ”. Very pleased that our Review is part of the 50th anniversary special edition of Trends in Biochemical Science. doi.org/10.1016/j.ti...
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Leann Tilley @leanntilley.bsky.social · 07/07/2025
Amazing Public Lecture by Nobel Laureate Donna Strickland, Nobel Prize in Physics in 2018, at RMIT’s Capitol Theatre. Strickland pioneered chirped pulse amplification for lasers, enabling innovations such as laser eye surgery. She gave an inspirational talk about her love of photons.
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Leann Tilley @leanntilley.bsky.social · 30/06/2025
Very pleased to participate in an amazing Women in Parasitology session today as part of the Australian Society for Parasitology (@AS_Para) 2025 Conference. Thanks very much to Facilitators: Ghizal Siddiqui (@G__Siddiqui) and Hayley Bullen.
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Leann Tilley @leanntilley.bsky.social · 29/06/2025
I thoroughly enjoyed attending the Symposium for the 50th Anniversary of the WEHI Parasitology and Infectious Diseases Division. It was great to meet up with friends and colleagues, such as Prof Emeritus Robin Anders and Prof William Pomat, Director of the PNG Institute of Medical Research.
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Leann Tilley @leanntilley.bsky.social · 13/03/2025
Congratulations from all the Tilley Lab to Nutpakal Ketprasit (@nkprst) who submitted his thesis today on reaction hijacking of tRNA charging enzymes of Plasmodium & bacteria. This work will guide development of new treatments. Co-supervised by Stanley Xie and Stuart Ralph (@sturalph). @UniMelb
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Leann Tilley @leanntilley.bsky.social · 04/03/2025
Thanks to the amazing and inspirational International Women's Day #IWD2025 Morning Tea Panel organised by the School of Biomedical Sciences @UniMelb. “It takes a village to raise a successful woman scientific leader”. Great buzz of collaboration and support at the event.
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Leann Tilley @leanntilley.bsky.social · 17/02/2025
Congratulations to Tayla Field, Stawell Secondary College, 2025 winner of the Chris & Marli Tilley Scholarship. Thanks to the Program run by Andrew McGuickan CEO. #Youthrive_Victoria is an amazing organisation supporting young rural and regional Victorians and their communities.
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Leann Tilley @leanntilley.bsky.social · 12/02/2025
A fantastic meeting #LorneProteins2025
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Leann Tilley @leanntilley.bsky.social · 11/02/2025
I had the great pleasure and honour of Chairing a Special session @LorneProteins. A History of the Lorne Conference on Protein Structure and Function. The event marked the 50th Anniversary. 5 decades of Lorne-inspired protein science in Australia - remembered by 5 amazing colleagues.
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Leann Tilley @leanntilley.bsky.social · 11/02/2025
Inspirational women discussing science @LorneProteins and life at 7.30 am in Lorne, as part of the #GWB breakfast network.
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Leann Tilley @leanntilley.bsky.social · 09/02/2025
Congratulations to @FrancesBiophys on the award of the 2025 Leach Lecture Medal of the Lorne Proteins Conference. Frances gave an inspirational talk about NMR and of a life lived fully. What a wonderful role model for women in science! @LorneProteins
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Leann Tilley @leanntilley.bsky.social · 09/02/2025
Great talk from Hannah Shafaat UCLA on how to make a minimal metaloprotein @lorneproteins.bsky.social
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Reposted by Leann Tilley
Rachel Maddow @maddow.bsky.social · 04/02/2025
"Two-thirds of the staff of the President’s Malaria Initiative, an organization founded by former President George W. Bush, have been fired, including some of the most senior and respected scientists working on malaria control in the world..." www.nytimes.com/2025/02/01/h...
nytimes.com
Health Programs Shutter Around the World After Trump Pauses Foreign Aid
Lifesaving treatment and prevention programs for tuberculosis, malaria, H.I.V. and other diseases cannot access funds to continue work.
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Leann Tilley @leanntilley.bsky.social · 03/02/2025
The ASTMH has written an open Letter to Secretary of State, Marco Rubio, calling on America to sustain its leadership in global health security. www.astmh.org/blog/january... A concerted effort is needed to fight infectious diseases, including emerging diseases that affect the entire world.
astmh.org
ASTMH - ASTMH Letter to Secretary of State Marco Rubio: America Needs to Sustain Its Leadership in Global He
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Leann Tilley @leanntilley.bsky.social · 03/02/2025
Please read this important article from the New York Times by @stephanienolen.bsky.social . The shut down of Programs on HIV, TB and malaria for 90 days and the attack on the agenda of USAID is a very sad day for people who benefit from and care about global health initiatives.
nytimes.com
Health Programs Shutter Around the World After Trump Pauses Foreign Aid (Gift Article)
Lifesaving treatment and prevention programs for tuberculosis, malaria, H.I.V. and other diseases cannot access funds to continue work.
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Leann Tilley @leanntilley.bsky.social · 19/12/2024
Excited to see our study published in @PLOSPathogens. Multi-stage activity & single oral dose killing of P. falciparum in vivo. Structural basis for improved potency and selectivity of this reaction-hijacking inhibitor are revealed. doi.org/10.1371/journal.ppat.1012429
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Reposted by Leann Tilley
WHO @who.int · 13/12/2024
2.2 billion #malaria cases and 12.7 million deaths have been averted since 2000 Find out more in the new WHO World Malaria Report 2024: 👉 bit.ly/4g31og6
A father, son and mother stand together in the doorway of their brick house.
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Leann Tilley @leanntilley.bsky.social · 10/12/2024
The Biomolecular Horizons 2024 (BMH2024) Congress welcomed registrants from 44 countries to share new developments in biomolecular research, innovation and education. The Congress made possible by the work of some many amazing colleagues. Read the Report in the AB: lnkd.in/gbA7Hf_E Page 31-37.
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Reposted by Leann Tilley
Brett Collins @brettcollins.bsky.social · 17/11/2024
An amazing cryoEM structure of the membrane-assembled lysosomal mTORC complex from the Hurley lab. @jimhurley.bsky.social www.biorxiv.org/content/10.1...
Structure of mTORC complex by cryoEM showing electron density maps
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Reposted by Leann Tilley
Fiona Whelan @freewhelan.bsky.social · 17/11/2024
That's a wrap! With this awesome crew of go getters 🤩 We pulled off such a smooth huge conference! Thanks to all the #bmh2024 speakers, attendees and the never say die organisers. A privilege to work with you all! Let's never attempt this again 🫡
A group of Australian academics standing shoulder to shoulder, celebrating organising the successful Biomolecular Horizons Congress 2024, Melbourne, Victoria.
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Reposted by Leann Tilley
Fiona Whelan @freewhelan.bsky.social · 18/11/2024
C/O the #adelaideproteingroup The Lorne Proteins Conference 2025 is coming up! Feb 9–13, 2025, it’s a must for protein science enthusiasts. 🇦🇺 Lorne, Victoria 💡 Connect with international experts, share your research, and explore the latest advancements. 📅 Register now: lorneproteins.org
lorneproteins.org
Lorne Proteins 2025
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Leann Tilley @leanntilley.bsky.social · 28/11/2024
Wonderful to hear inspirational speakers from @YouthriveVic at the breakfast at Parliament of Victoria, this morning. Thanks to Maree Edwards, Speaker of the Victorian Legislative Assembly, for hosting, and to Andrew McGuckian for organising the event.
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Leann Tilley @leanntilley.bsky.social · 24/11/2024
Congratulations to Frances Separovic on being awarded a Docteur Honoris Causa from the University of Bordeaux. @FrancesBiophys
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Leann Tilley @leanntilley.bsky.social · 22/11/2024
Congratulations to the team.
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Leann Tilley @leanntilley.bsky.social · 14/11/2024
So lovely to join the celebrations for the 2024 L’Oréal-UNESCO For Women in Science celebration. Congratulations to the amazing award winners. Great to catch up with wonderful @Women in Science. @DrMistyJenkins
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Leann Tilley @leanntilley.bsky.social · 22/10/2024
Congratulations @Kelly_Chibale on being elected to the United States National Academy of Medicine! nam.edu/national-academy-of-medicin… Kelly discovered the first small molecule clinical candidate for any disease, researched on African soil by an...
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Leann Tilley @leanntilley.bsky.social · 02/10/2024
Stories & Structures – New Connections. #BMH2024 featured an exhibition building on >60,000 yrs of Indigenous tradition in a collaboration with Microscopy Australia. Rich visual parallels between #Indigenous artworks and the microscopic world. Thanks to Jenny Whiting @Sydney_Uni
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Leann Tilley @leanntilley.bsky.social · 26/09/2024
Excellent session on emerging pathogens! Lots to be scared about.
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Leann Tilley @leanntilley.bsky.social · 26/09/2024
Everything you always wanted to know about Publishing but were too scared to ask. Great session.
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Leann Tilley @leanntilley.bsky.social · 25/09/2024
Thanks Laura Edgington-Mitchell. Thanks Beth and Lou. Thanks Tony Chiovitti, GTAC. @LauraEM_Lab
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Leann Tilley @leanntilley.bsky.social · 25/09/2024
Brilliant #BMH2024 High School Holiday Program. From microbial machines to gene editing therapies Amazing presentations from Dr. Alexis Komor, University of California San Diego, Dr. Melinda Jingqi Wang & Dr. Rhys Grinter, University of Melbourne. @Rhys__G @KomorLab
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Leann Tilley @leanntilley.bsky.social · 25/09/2024
Alexis Komor (@Komor_Lab) is a leader in #precision #genome_editing. She has developed new base editing methods that overcome problems with off target genome changes. Her work greatly advances efforts towards gene editing repair of genetic mutations.
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Leann Tilley @leanntilley.bsky.social · 25/09/2024
Caixia GAO is at the forefront of developing CRISPR-modified rice and wheat strains to secure the world’s food supplies. She wowed us with stories of “scarless” and base editing strategies. Her team’s mildew resistant wheat has achieved registration. #Bmh2024
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Leann Tilley @leanntilley.bsky.social · 24/09/2024
Rich asks us to use our influence for the good of Society. He points to a need for all scientists to advocate to the public and to politicians about science-based solutions to the world’s challenges. #BMH2024
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Leann Tilley @leanntilley.bsky.social · 24/09/2024
Erinna (@erinna_lee) and Marilyn Anderson in conversation with Nobel Prize winner, Sir Rich Richards. Rich says: Embrace your “failed” experiments. If you repeatedly get an unexpected result, Nature is trying to tell you something.
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Leann Tilley @leanntilley.bsky.social · 24/09/2024
@PetroTerblanche, CEO Afrigen, advocates the medicines that Africa’s population could be manufactured on the African continent. RNA Technology offers the possibility of leap-frogging barriers to manufacture, but problems remain with respect to gaining IP and licences. #BMH2024
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Leann Tilley @leanntilley.bsky.social · 24/09/2024
Sage words from the Future of RNA Technology Panel @bmh2024Melb. Thanks to Amanda Caples, Victoria’s Lead Scientist, Australia Catherine Mills, Monash Bioethics Institute Steve Rockman, CSL/Seqiris, Australia Claire Borg, Moderna, Australia @traude_beilharz
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Leann Tilley @leanntilley.bsky.social · 24/09/2024
Photo of the successful bid team for @BMH2024Melb in Seoul in 2018. Here we are 6 years later. Our dream realised!
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Leann Tilley @leanntilley.bsky.social · 24/09/2024
Great overview of and insights into RNA vaccines from Norbert Paradise at @bmh2024Melb Plenary Talk
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Leann Tilley @leanntilley.bsky.social · 23/09/2024
Good times at the BMH2024 mixer! (@BMH2024Melb)
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Leann Tilley @leanntilley.bsky.social · 23/09/2024
A very sage Indigenous Perspectives in BioMolecular Science Panel fielded questions about how to work with Indigenous patients, colleagues and sample in a respectful way. Amazing insights. How to be a good ally. Build on deep consultation. Such important work. Amazing insights.
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Leann Tilley @leanntilley.bsky.social · 23/09/2024
Misty Jenkins AO (@DrMistyJenkins @WEHI_research) gave a Plenary Talk on #CAR-T therapies, and #brain_cancer. She is so amazing, I got a bit emotional! @DrMistyJenkins @WEHI_research.
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Leann Tilley @leanntilley.bsky.social · 23/09/2024
Wow. The Indigenous Perspectives in BioMolecular Science stream @BMH2024Melb has been amazing . The Day showcased top #Indigenous researchers covering topics from #Cancer and #Immunology, to #Climate Change to #Genomics, to #Education. @UniMelbPoche @KimiHenare
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Leann Tilley @leanntilley.bsky.social · 22/09/2024
Birrarung by night. SNAP SHOT MELBOURNE! Take a selfie with an iconic Melbourne feature whilst you enjoy @BMH2024Meb. Submit your images at forms.gle/k2WyxWQAEwzcBFoCA to win great prizes.
forms.gle
BMH Competition Submission Portal
Have you heard of our amazing competitions? We cover a br...
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Leann Tilley @leanntilley.bsky.social · 22/09/2024
The @BMH2024Melb Career Development Event is amazing. What a terrific line-up of speakers. Some photos from the event. . @Komor_Lab @DrDanDries @SomeBlondeSci @gl_alisa @SarahGarnish
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Leann Tilley @leanntilley.bsky.social · 21/09/2024
Kick-off at the Molecular Neuroscience Satellite of Biomolecular Horizons (@BMH2024Melb). Great talk on molecular determinants of memory by Bong-Kium Kaang. Introduced by @AnggonoLab and IUBMB President-elect @DrMJMaher
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Leann Tilley @leanntilley.bsky.social · 20/09/2024
Lovely to catch up with colleagues from KSBMB ahead of the Molecular #Neuroscience Biomolecular Horizons Satellite one-day meeting (21 September 2024). @BMH2024Melb. Featuring speakers from Australia and South Korea. Thanks Victor @AnggonoLab
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Leann Tilley @leanntilley.bsky.social · 19/09/2024
The Young Scientists Program delegates have arrived for the @BMH2024Melb/ @IUBMB/ #FAOBMB event ahead of the BioMolecular Horizons Congress. Lots of fun and science ahead for the next few days. Thanks to @DrGabbyWatson and the YSP team for organising.
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Leann Tilley @leanntilley.bsky.social · 19/09/2024
Visit bmh2024.com/program/schedule to see the amazing line-up of @BMH2024Melb speakers, including Alexandra talking about #PKC, #cancer. #cell_signaling #cell_biology.
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