iiinova — where your digital self keeps evolving

Reposted by Leire Bejarano Bosque

Ludwig Cancer Research @ludwigcancer.bsky.social · 26/01/2026

A team led by Ludwig @unil.bsky.social’s @lbejarano.bsky.social & @johannajoyce.bsky.social has discovered that a protein made by cancer cells, CD13, helps them establish colonies in the brain—identifying a potential drug target for the prevention or treatment of brain metastases. bit.ly/4afX64r

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Johanna Joyce @johannajoyce.bsky.social · 22/01/2026

Why do so few cancer cells manage to form metastases - and what helps the rare ones succeed? Delighted to share our first publication of 2026 🎉🎉, led by the outstanding @lbejarano.bsky.social 🤩, where we reveal some insights into this - focusing on brain metastasis 🧠🧪🔬 www.cell.com/cell-reports...

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Reposted by Leire Bejarano Bosque

Johanna Joyce @johannajoyce.bsky.social · 04/09/2025

Congratulations to all the ERC Starting Grant awardees 🧪 including @alvarezprado.bsky.social & @lbejarano.bsky.social, two brilliant former postdocs from my lab who have started their own labs this year in 🇱🇺 and 🇪🇸 Could not be more proud of Leire and Ángel 🤩 🎉 🎉 🎉 #proudmentor 😊 #ERCStartingGrant

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Leire Bejarano Bosque @lbejarano.bsky.social · 04/09/2025

Thrilled to share that I’ve been awarded an ERC Starting Grant for the METAVASC project, focused on studying the vasculature in brain mets 🙏🎉 Huge thanks to the ERC, mentors & collaborators that made this possible! We’ll soon recruit PhDs, postdocs & techs, stay tuned😊 @erc.europa.eu #ERCStG

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Johanna Joyce @johannajoyce.bsky.social · 03/09/2025

How can we reawaken the body’s own anti-viral defenses to fight brain cancer? Delighted to share our new study where we now answer this question, led by the brilliant @alvarezprado.bsky.social who is now an independent PI at LIH Luxembourg 👏👏 #BrainTIME 🧠🦠🧪 🧵 www.sciencedirect.com/science/arti...

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Leire Bejarano Bosque @lbejarano.bsky.social · 29/06/2025

Truly honored to receive the 'Young Researcher in Basic Sciences Award' from the Faculty of Biology and Medicine, University of Lausanne! 🧠 ✨ Huge thanks to Johanna Joyce for her excellent mentorship, support, and inspiration — I’m incredibly grateful! And congrats to all the other awardees! 🎉

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Leire Bejarano Bosque @lbejarano.bsky.social · 28/05/2025

After a memorable journey in the Joyce Lab, it’s time to start a new adventure. I will always be grateful for the extraordinary mentorship and support of @johannajoyce.bsky.social. I'm excited to share that I will start as a #NewPI at the Biogipuzkoa HRI, in the beautiful city of San Sebastián 🙂

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Reposted by Leire Bejarano Bosque

Immunity @cp-immunity.bsky.social · 09/04/2025

New issue online! This beautiful cover depicts work from @johannajoyce.bsky.social @lbejarano.bsky.social &co who use single-cell RNA sequencing & spatial analysis to construct a vascular atlas of primary & metastatic brain tumors. Art by @joanagcc.bsky.social www.cell.com/immunity/iss...

The unveiling of vascular heterogeneity is depicted as a red pencil coloring in the intricate details of tumor-associated blood vessels within a map of the human brain wherein a tumor is surrounded by diverse immune cells.

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Johanna Joyce @johannajoyce.bsky.social · 08/04/2025

Excited to see our image on the cover of #Immunity today 🤩 Congrats to the amazing @lbejarano.bsky.social & all authors for our #brain #tumor #vasculature study www.cell.com/immunity/ful... Huge 🙏 🙏 to the v talented @joanagcc.bsky.social for creating this super cover 🧠🧪 @cp-immunity.bsky.social

On the cover: The blood-brain barrier is a defining feature of brain tumors, shaping their biology and therapeutic response. In this issue, Bejarano et al. use single-cell RNA sequencing and spatial analysis to construct a vascular atlas of primary and metastatic brain tumors, revealing distinct alterations in endothelial and mural cells. Glioblastomas undergo substantial vascular remodeling compared to low-grade gliomas, while brain metastases exhibit even greater permeability and increased immune cell interactions. This unveiling of vascular heterogeneity is depicted as a red pencil coloring in the intricate details of tumor-associated blood vessels within a map of the human brain wherein a tumor is surrounded by diverse immune cells. Image by Joana C. Carvalho.

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Johanna Joyce @johannajoyce.bsky.social · 31/03/2025

Why do brain metastases resist #immunotherapy — even when the same cancer responds outside the #brain? 🧠🧪💥 We just published a study diving into this question ⏬ Led by an amazing (former) PhD student in my lab —Vladimir Wischnewski 🎉 🧵 1/ @cp-cellreports.bsky.social www.cell.com/cell-reports...

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Ludwig Cancer Research @ludwigcancer.bsky.social · 24/03/2025

Study led by Ludwig @fbm-unil.bsky.social’s @johannajoyce.bsky.social and alumnus Vladimir Wischnewski explains why brain metastases of breast cancer are likely to resist potentially synergistic combinations of radiotherapy and checkpoint blockade #immunotherapy. Learn more: bit.ly/4kZTKGo #CanSky

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Johanna Joyce @johannajoyce.bsky.social · 20/03/2025

How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪 Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻 🧵 @cp-immunity.bsky.social www.cell.com/immunity/ful...

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Leire Bejarano Bosque @lbejarano.bsky.social · 20/03/2025

Thrilled to see our vascular atlas across primary and metastatic brain tumors finally out in Immunity! 😍 🍾 Thanks to @johannajoyce.bsky.social for her invaluable mentorship and to all the authors involved! 🎉

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