iiinova — where your digital self keeps evolving

Reposted by Lorenz Bastian

Edward Elderman @elderman.bsky.social · 09/08/2026

Andrew Wyeth 'Wind from the Sea' 1947. Tempera on hardboard The curtains

Lorenz Bastian @lbastianmd.bsky.social · 28/03/2026

Excited to share our latest study in Blood🩸: IGH enhancer redirection to FOXF1 and KRAS mutations, define a novel high-risk B-ALL subtype! Huge 🙏to collaborators Emmanuelle Clappier, Ilaria Iacobucci, @cmullighan.bsky.social and our team @uni-kiel.de. 🔗https://doi.org/10.1182/blood.2025031102

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Lorenz Bastian @lbastianmd.bsky.social · 20/02/2026

Our cross-age analysis of #KMT2A rearranged #B-ALL is out in @hemasphere-journal.bsky.social: advancing age 👶👵 is linked to immaturity🌱, chemotherapy resistance and poor outcome with RNA-seq providing a lense into these connections. 👏 to Alina Hartmann and our team! 📎 doi.org/10.1002/hem3...

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Reposted by Lorenz Bastian

Science Magazine @science.org · 22/01/2026

No bull: This Austrian cow has learned to use tools. Learn more: scim.ag/3LYTXNd

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Lorenz Bastian @lbastianmd.bsky.social · 08/01/2026

🎇 1st paper of the lab this year: IDH1 mutations downregulate IL1R1 in acute myeloid leukemia. IL1R1 low expression is enriched in IDH1-mutant AML and linked to 📈 better ouctome! 👏 to Sophie Steinhäuser, Simone Lipinski and team at #UKSH / @uni-kiel.de ! 🔗 rdcu.be/eYeg8

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Lorenz Bastian @lbastianmd.bsky.social · 03/01/2026

🌊Embarking to 2⃣0⃣2⃣6⃣ with our first preprint: Established on 2,314 T-ALL transcriptomes, ALLCatchR now discriminates 20 T-ALL gene expression subtypes, including an clonal-hematopoiesis cluster in adults! 🙏 Kudos to Thomas Beder! doi.org/10.64898/202...

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Lorenz Bastian @lbastianmd.bsky.social · 20/10/2025

Finally out📯: 1st population-level picture of AML+ALL incidence & outcomes across all age groups in Germany! My colleague David Baden took the long tour to aggregate this data: doi.org/10.1016/j.la... - Will be intro Figurę 1 to many presentations, David!🙏

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Reposted by Lorenz Bastian

Christoph Kaleta @kaletalab.bsky.social · 09/10/2025

1/4 🌍 We are looking for a passionate #PhD student in #Metabolic #Microbiome #Modeling in the Marie Skłodowska-Curie Doctoral Network MenoBrain. Join us at one of Europe’s microbiome research hubs and push the boundaries of microbiome science! @uni-kiel.de 🔗 www.uniklinikum-jena.de/menobrain/en...

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Reposted by Lorenz Bastian

bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 28/09/2025

IntegrateALL: an end-to-end RNA-seq analysis pipeline for multilevel data extraction and interpretable subtype classification in B-precursor ALL www.biorxiv.org/content/10.1101/202…

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Lorenz Bastian @lbastianmd.bsky.social · 28/09/2025

Excited to share our preprint📯: We introduce #IntegrateALL, an open-source RNA-seq pipeline for interpretable molecular diagnostics in acute lymphoblastic leukemia!🧬 Big thanks to Nadine Wolgast & team @ www.uksh.de , catchall-kfo5010.com! See: doi.org/p7k5 and 🧵

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Lorenz Bastian @lbastianmd.bsky.social · 07/08/2025

Finally some larger perspective after a long day on call… 🚀

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Lorenz Bastian @lbastianmd.bsky.social · 24/07/2025

What determines Inotuzumab sensitivity in #ALL? New @bloodjournal.bsky.social study from C. Escherich & @junjyang.bsky.social Lab highlights the role of B cell developmental state and EBF1. It was a pleasure to provide a commentary! 🔬 doi.org/10.1182/bloo... 🗒️ doi.org/10.1182/bloo...

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Lorenz Bastian @lbastianmd.bsky.social · 20/06/2025

@Hemasphere_EHA acknowledged our ALLCatchR paper on machine learning based subtype classification in ALL as highly influential publication! 💥So happy and grateful! Big kudos to Thomas and our team at 👉catchall-kfo5010.com #EHA2025

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