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Reposted by Laurent LE

bioRxiv Bioengineering @biorxiv-bioeng.bsky.social · 02/10/2026

BrightEyes-Scope: A Reference Implementation for Image Scanning Microscopy with SPAD Array Detection www.biorxiv.org/content/10.64898/20…

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Reposted by Laurent LE

Massive Photonics @massivephotonics.bsky.social · 10/06/2026

New paper alert! Le et al. introduce brightness demixing, a method that distinguishes fluorophores by their photon flux rather than spectral properties. Congrats! Authors used our #DNAPAINT reagents to image clathrin, tubulin, vimentin, & nuclear pores. 🔗 www.nature.com/articles/s41...

nature.com

Brightness demixing for simultaneous multi-target imaging in 3D single-molecule localization microscopy - Nature Methods

Brightness demixing is a method for simultaneously detecting different fluorophores in single-molecule localization microscopy based on their brightness rather than their spectral properties. As this ...

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Reposted by Laurent LE

VicidominiLab @vicidominilab.bsky.social · 13/10/2025

Big thanks to Andrea Bucci and @laurent-le.bsky.social for the 13h drive with a microscope in the trunk...and setting it up! First workshop #MifoBio2025 done, challenge won. A #SPADarray in any laser-scanning microscope. @genoainstruments.bsky.social @iitalk.bsky.social @gdrimabio.bsky.social

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Reposted by Laurent LE

Sandrine Lévêque Fort 🔬 @slfort.bsky.social · 04/03/2025

🔬Happy to share our new preprint, where brightness is used to identify single molecule emission in 2D/3D, with a single camera ! Part of the PhD work of @laurent-le.bsky.social and Surabhi, great collaboration with @emmanuelfort.bsky.social from @instlangevin.bsky.social @ismolab.bsky.social #SMLM

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Reposted by Laurent LE

Sandrine Lévêque Fort 🔬 @slfort.bsky.social · 16/01/2025

And last but not least Laurent Le from the team on part of his PhD work @ismolab.bsky.social

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