iiinova — where your digital self keeps evolving

Reposted by Lara Busby

Matt Towers @matt-towers.bsky.social · 02/07/2026

Pleased to share our latest! We show that the chick limb can be directed to recapitulate key stages in mammalian evolution, providing a unifying model for digit patterning across amniotes. Preprint: www.biorxiv.org/content/10.6... Video summary: www.youtube.com/watch?v=fvL_...

biorxiv.org

Transforming avian to mammalian modes of digit patterning

How a conserved embryonic organiser-the Sonic hedgehog (Shh)-expressing Zone of Polarising Activity (ZPA)-generates diverse limb architectures in amniotes remains a central problem in evolutionary and...

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Reposted by Lara Busby

Molecular Instruments, Inc. @hcrimaging.bsky.social · 18/06/2026

A preprint from Martik Lab revealed a layer of Twist1 regulation during cranial neural crest development. @laracbusby.bsky.social shared, "The sensitivity of HCR™ staining allowed us to observe transcripts that would have been missed with traditional ISH staining." Read more: tinyurl.com/32r6exrn

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Reposted by Lara Busby

Alex Neaverson @alexneaverson.bsky.social · 07/04/2026

I illustrated my way through the @bsdb.bsky.social Spring Meeting a couple weeks ago - here's my illustrated summary of the conference! I sketched (almost) all the speakers and glimpses of the science that made it such a great few days.

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Reposted by Lara Busby

Ben Steventon @bensteventon.bsky.social · 23/03/2026

Happy to share this work from @alexneaverson.bsky.social where she has dissected the timing and relative contribution of the organiser and its derivates to multiple aspects of early neural development: www.biorxiv.org/content/10.6...

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Reposted by Lara Busby

Matt Towers @matt-towers.bsky.social · 16/02/2026

PDRA position still open in my lab for anyone who wants to solve some outstanding questions in limb development. We have a variety of models and approaches (everything from stem cells to chicks and catsharks). Please share!

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Reposted by Lara Busby

Lucy Dornan @lucygdornan.bsky.social · 12/12/2025

A glittery, festive #FluorescenceFriday today, spent playing with some fun samples 🪩🕺

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Reposted by Lara Busby

Yuri Takahashi @yuritakahashi.bsky.social · 05/12/2025

Hi bsky! How do cells coordinate fate with migration during development? 🐣 Turns out EMT doesn't just drive cell behaviour changes... it actively primes BMP signalling competence, creating a reciprocal coupling that drives collective invasion! (@bensteventon.bsky.social lab) tinyurl.com/2ncc8zap

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Lara Busby @laracbusby.bsky.social · 25/06/2025

Back from SDB in Puerto Rico! A lovely week spent with new and old friends, daily pool breaks and a multitude of pina coladas 🍹

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Reposted by Lara Busby

Peter Fabian @fabianlab.bsky.social · 21/11/2024

Check out how #neuralcrest cells 🔬 migrate (animal= #zebrafish, white cells=sox10+, start=10 somites stage, anterior=top)

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