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Eran Perlson

@labperlson.bsky.social

Professor, Head of the Laboratory of Molecular and Cellular Mechanisms of Neurodegenerative Diseases, Axonal Transport and Local Synthesis, NMJ

Posts Replies Media

Reposted by Eran Perlson

Mike Fainzilber @mfainzilber.bsky.social · 16/05/2025

Online now at @cp-cell.bsky.social , the culmination of a 12-year effort. 🧵 to follow later this evening www.cell.com/cell/fulltex...

cell.com

Repeat-element RNAs integrate a neuronal growth circuit

SINEs of recovery: A subset of small RNAs encoded by repetitive genomic elements are induced by nerve lesion to regulate protein synthesis and enhance axonal growth.

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Reposted by Eran Perlson

Mike Fainzilber @mfainzilber.bsky.social · 16/05/2025

A 🧵 to walk those interested through this paper...

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Reposted by Eran Perlson

Nature @nature.com · 15/04/2025

This powerful and unbiased way to identify links between genetic variants and biological traits has changed scientists’ understanding of complex diseases and how to treat them go.nature.com/3RPTMTG

go.nature.com

Twenty years of genome-wide association studies

The first robust association between a genetic variant and disease risk.

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Reposted by Eran Perlson

Polymenidou Lab @polylab.bsky.social · 28/03/2025

Happy to share our new study that was just published in Neuron! www.cell.com/neuron/fullt...

cell.com

Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures

TDP-43 pathology characterizes neurodegenerative diseases. Scialò et al. use in vitro-generated and patient-derived TDP-43 aggregates as seeds to show that seed-induced TDP-43 cytoplasmic aggregation ...

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Reposted by Eran Perlson

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/03/2025

MicroRNAs alteration and unique distribution in the soma and synapses of substantia nigra in Parkinsons disease www.biorxiv.org/content/10.1101/202…

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Reposted by Eran Perlson

Oxford MND Research @mndoxford.bsky.social · 29/01/2025

Perspective, led by Martin, on the current application and future potential for blood neurofilament light chain level in neurological disorders, including #ALS pubmed.ncbi.nlm.nih.gov/39845125/

pubmed.ncbi.nlm.nih.gov

Blood level of neurofilament light chain as a biomarker for neurological disorders - PubMed

Blood level of neurofilament light chain as a biomarker for neurological disorders

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