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Kylene Harold

@kyharold.bsky.social

98 followers 103 following 3 posts

Forever fascinated by the heart🫀.

Posts Replies Media

Reposted by Kylene Harold

Ken Humphries @ken-humphries.bsky.social · 05/02/2026

Can "glitches" in how the heart processes sugar lead to dangerous arrhythmias? 🍬➡️💔 Our new study now in preprint shows that glycolytic dysregulation at the PFK nexus is enough to cause electrical instability in the heart. Check out our findings here:

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Kylene Harold @kyharold.bsky.social · 29/04/2025

Incredible friend, peer mentor, adventurous collaborator (patcher of “bricks”), and now DR. Blankenship @harrisedwardb.bsky.social defended the most brilliant dissertation yesterday.

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Kylene Harold @kyharold.bsky.social · 30/11/2024

Excellent review highlighting maladaptive implications of sustained O-GlcNAcylation in the diabetic heart, as well as gaps in understanding of the mechanisms underlying cardiac O-GlcNAc regulation.

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Reposted by Kylene Harold

Ken Humphries @ken-humphries.bsky.social · 20/11/2024

O-GlcNAc modification of enzymes within the N-glycosylation pathway impacts their function, revealing a connection between these two distinct glycosylation pathways. www.cell.com/cell-reports...

cell.com

O-GlcNAcylation modulates expression and abundance of N-glycosylation machinery in an inherited glycosylation disorder

Matheny-Rabun and colleagues discover that O-GlcNAc modification of rate-limiting enzymes within the N-glycosylation pathway impacts their function, drawing a connection between two spatially separate...

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Reposted by Kylene Harold

Ken Humphries @ken-humphries.bsky.social · 12/11/2024

Humphries lab, represent. Grad student, Kylene Harold, presenting her work on our PFKFB2 knockout mouse. 🫀

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Reposted by Kylene Harold

Aging and Metabolism @am-omrf.bsky.social · 15/11/2024

How’s this for a first post? New publication in Nature Communications about the role of dopamine in Alzheimer’s disease⤵️ omrf.org/2024/11/12/o...

omrf.org

OMRF discovers new chemical link to Alzheimer’s

Findings may explain mood changes that precede disease

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