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Kristiaan Wouters

@kwouters.bsky.social
126 followers 156 following 18 posts

Associate Professor Translational Immunometabolism Maastricht University. Immunologist investigating cardiometabolic diseases. Likes science, music and sports. Loves his wife and kids.

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Kristiaan Wouters @kwouters.bsky.social · 22/06/2026
Great to be part of the 1st #EURESOLVE Conference in Porto, where I presented our work on immunophenotyping, engage with the Resolution Biology community, and see Tia deliver an excellent presentation on sex differences in #MASLD. As WG5 Co-Lead: join us to build a Resolution Biology knowledge hub!
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Kristiaan Wouters @kwouters.bsky.social · 03/06/2026
Now published in European Journal of #Immunology: We show that multiple autofluorescence extraction is essential to accurately identify and quantify hepatic macrophage subsets in #MASH livers with #FlowCytometry. Default methods are often insufficient for complex, highly autofluorescent tissue.
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Kristiaan Wouters @kwouters.bsky.social · 28/03/2026
Publication alert! Review on "adipose tissue-derived microvesicles of endothelial dysfunction in obesity" resulting from a fruitful and fun collab with @biekebroux.bsky.social. Great effort of our joint PhD students Daphne Lintsen and @lisatschuetz.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Adipose tissue-derived extracellular vesicles as drivers of endothelial dysfunction in obesity
Obesity and (white) adipose tissue (AT) inflammation are closely linked to endothelial dysfunction (ED) and neurological conditions associated with an…
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Kristiaan Wouters @kwouters.bsky.social · 01/02/2026
New preprint! Liver macrophages are highly autofluorescent cells, complicating analysis. @sabinedaemen.bsky.social developed a spectral flow approach to resolve #macrophage subsets in healthy vs #MASLD livers. #FlowCytometry #SpectralFlow #Autofluorescence doi.org/10.64898/202...
doi.org
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Kristiaan Wouters @kwouters.bsky.social · 24/01/2026
Happy to share our latest publication showing that higher neutrophils and monocytes, but not other leukocytes, were linked to lower heart rate variability — a sign of reduced flexibility in how the heart responds to daily demands. www.ahajournals.org/doi/10.1161/... #inflammation #cardiovasular
ahajournals.org
Circulating Neutrophil and Monocyte Counts Are Inversely Associated With Heart Rate Variability Indices: The Maastricht Study | Journal of the American Heart Association
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Kristiaan Wouters @kwouters.bsky.social · 19/01/2026
📄 New paper published in Frontiers in Physiology! We show that pyridoxamine reduces inflammation and microcirculatory dysfunction in MASH, modulating key hepatic AGE/ALE signaling pathways. 🔗 doi.org/10.3389/fphy... #MASH #LiverDisease #Inflammation
doi.org
Frontiers | Pyridoxamine reduces inflammatory and microcirculatory abnormalities in metabolic dysfunction-associated steatohepatitis and modulates key factors in the hepatic AGE/ALE signaling pathway
Metabolic dysfunction-associated steatohepatitis (MASH) is an increasing public health concern for which new therapies are urgently needed. As growing eviden...
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Kristiaan Wouters @kwouters.bsky.social · 31/12/2025
At the dawn of 2025, I received the second notification this week of an accepted manuscript. A wonderful way to close out 2025 and step into 2026 with renewed motivation and momentum. I wish everyone a Happy New Year and all the very best for the year ahead!
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Reposted by Kristiaan Wouters
Journal of Experimental Medicine @jem.org · 03/12/2025
Fetal liver #macrophages support red blood cell production and pyrenocyte clearance in the developing embryo. Stifter, Greter et al. demonstrate that XPR1, a phosphate exporter and regulator, is required for the development and function of fetal liver macrophages. rupress.org/jem/article/...
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Kristiaan Wouters @kwouters.bsky.social · 03/12/2025
Today I presented our data on sex differences in experimental #MASH development at the MASLD-EGIR Study group meeting in Pisa showing earlier #steatosis, #inflammation and glucose intolerance in females but more fibrosis in males. Great conference! @gastaldelli-amy.bsky.social
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Kristiaan Wouters @kwouters.bsky.social · 26/11/2025
Thrilled and honoured to chair the #VeniVidiVici session at #CARIMday2025! It's inspiring to see so many talented researchers achieving success in securing grants. Especially proud to serve as Chair of the Carim Research Council and witness this incredible progress! 👏🎉 @carimmaastricht.bsky.social
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Reposted by Kristiaan Wouters
CARIM @carimmaastricht.bsky.social · 26/11/2025
@sabinedaemen.bsky.social investigates how immune cells can repair liver fibrosis. A big step toward fighting one of the world’s most pressing metabolic diseases and emerging CVD risk factor. #CARIMday2025 #MASLD #Veni
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CARIM @carimmaastricht.bsky.social · 26/11/2025
Join now on www.youtube.com/live/17cD_lN... for our annual CARIM+HVC Symposium
youtube.com
CARIM+HVC Symposium 2025
YouTube video by Maastricht University
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Reposted by Kristiaan Wouters
CARIM @carimmaastricht.bsky.social · 26/11/2025
@tilman-hackeng.bsky.social kicks off the #CARIMday2025. It will be a great day to celebrate #Cardiovascular research and working together.
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Kristiaan Wouters @kwouters.bsky.social · 14/11/2025
At the #ADDRM, @sabinedaemen.bsky.social, postdoc in my group, presented her work on sex differences in a mouse model of #MASH, an area where most data still rely on male mice. She found sex-specific differences in hepatic steatosis, fibrosis progression, and glucose intolerance.👏🐭🔬
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Reposted by Kristiaan Wouters
Sophie Acton @actonlab.bsky.social · 21/10/2025
We hiring! Please share this post with your talented ECRs We're looking for a postdoc interested in the formation and function of tertiary lymphoid structures - project funded by Wellcome Based at @lmcb-ucl.bsky.social at University College London Apply here: www.jobs.ac.uk/job/DPD418/r...
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Kristiaan Wouters @kwouters.bsky.social · 17/10/2025
Kicked off the #EU-RESOLVE COST Action last week - a network advancing research on #inflammation #resolution I co-lead WG5, building a Knowledge Hub on insights in resolution biology. We want this hub to grow, so join us and help shape this valuable resource! www.cost.eu/actions/CA24138/
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Kristiaan Wouters @kwouters.bsky.social · 17/10/2025
Kicked off the #EU-RESOLVE COST Action last week - a network advancing research on #inflammation #resolution I co-lead WG5, building a Knowledge Hub on insights in resolution biology. We want this hub to grow, so join us and help shape this valuable resource! www.cost.eu/actions/CA24138/
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Reposted by Kristiaan Wouters
CARIM @carimmaastricht.bsky.social · 16/06/2025
#thesisdefence Tomorrow, Sara D'Haese will defend the thesis 'Mitigating diabetic cardiomyopathy: Evaluating exercise training and pyridoxamine as cardioprotective approaches’ at 16:00h @maastrichtu.bsky.social @kwouters.bsky.social‬ 📺 buff.ly/1VrmD4j 📖 #phdlife #phddefence #GradSchool #doctorate
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Kristiaan Wouters @kwouters.bsky.social · 07/06/2025
What.A.Guy. Best advice and applicable to about everything. "Stop whining. What are You doing?" There will always be obstacles. @schwarzenegger.bsky.social www.bbc.com/news/videos/...
bbc.com
Schwarzenegger: Hey, stop whining, do something on climate change
The actor and activist was speaking to the BBC at a summit organised by his Climate Initiative.
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Kristiaan Wouters @kwouters.bsky.social · 05/05/2025
Inspiring presentation of Gemma Figtree at #EASCongress2025 on treating #atherosclerosis as a disease rather than traditional risk factors, especially considering that 25% of MI patients show none of them.
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Kristiaan Wouters @kwouters.bsky.social · 04/05/2025
#EASCongress2025 kicks off with a bang. Paul Ridker gives the Anitschkow lecture on targeting #inflammation to target #atherosclerosis. #cardiovascular #CVD
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Kristiaan Wouters @kwouters.bsky.social · 16/01/2025
Kudos @GCN for a balanced analysis on claims that #exercise does not induce #weightloss: www.youtube.com/watch?v=vUGF... As mentioned here (bjsm.bmj.com/content/59/2...) it's about adherence. For me, first 20-25kg were dietary pattern changes (not dieting), the next few kg definitely exercise.
youtube.com
The Biggest Lie About Weight Loss And Exercise
YouTube video by Global Cycling Network
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Kristiaan Wouters @kwouters.bsky.social · 19/12/2024
Happy to share our latest publication showing that adiposity differentially affects immune cells in fat depots based on #sex during #obesity development. rdcu.be/d36Dx. @lisatschuetz.bsky.social al @biekebroux.bsky.social roux.bsky.social #immunosky
rdcu.be
Sex differentially affects pro-inflammatory cell subsets in adipose tissue depots in a diet induced obesity model
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Thiago Carvalho @cyrilpedia.bsky.social · 06/12/2024
A review for those of us (me!) who only really know foamy macrophage in the context of cardiovascular pathology: #immunology journals.aai.org/jimmunol/art...
journals.aai.org
An Insight into the Role of IL-10 and Foamy Macrophages in Infectious Diseases
Abstract. Dysregulation of lipid homeostasis causes the deposition of lipids in the form of tiny droplets within foamy macrophages (FMs). In FMs, host-deri
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