iiinova — where your digital self keeps evolving

Reposted by Karla Valdivieso

International Cell Senescence Association @icsasenescence.bsky.social · 19/08/2026

🏆 #ICSAPaperOfTheMonth Telomere shortening has long been considered a cause of cellular senescence. Fabrizio d'Adda and team now show telomeric DNA damage signalling is itself a causal driver of hematopoietic decline. www.nature.com/articles/s43... @nataging.nature.com

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Reposted by Karla Valdivieso

International Cell Senescence Association @icsasenescence.bsky.social · 06/10/2026

What happens to a macrophage that is infected for a long time? Senescence! Once we clear those senescent cells with senolytics, the bacterial burden drops. This is a new way to tackle infections without using antibiotics. Link in comment! #ICSAPaperOfTheMonth @edoardoscarpanti.bsky.social

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Reposted by Karla Valdivieso

oZgun Gokce @gokcegroup.bsky.social · 11/10/2026

⏳ 21 days left to submit your #FRM2027 symposium proposal. The keynote line-up is set. Now we need your symposia to complete the programme. Deadline: 1 November. See you in Istanbul. 👉 frm2027.org Please repost. #FRM2027 #SynapseOfContinents #FENS #Neuroscience

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Reposted by Karla Valdivieso

International Cell Senescence Association @icsasenescence.bsky.social · 01/09/2026

In the #ICSAPaperOfTheMonth, the Passos and @adamsbioaging.bsky.social lab reveal how mitochondrial metabolism controls the SASP through epigenetic regulation. Targeting mitochondrial citrate transport reduces inflammation and improves healthspan in aged mice. Link 👉 www.nature.com/articles/s41...

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Reposted by Karla Valdivieso

International Cell Senescence Association @icsasenescence.bsky.social · 06/07/2026

Senescence isn't just aging, it can be fast and functional. New work from Valdivieso & Rozmarič @lbitrauma.bsky.social shows "aged" cells coordinate wound healing within hours of injury, challenging the classic view. Interview with the authors: www.cellsenescence.info/post/copy-of...

cellsenescence.info

PotM - June 2026

Transcription-independent induction of rapid-onset senescence is integral to healingValdivieso, K., Rozmaric, T., et al., Nature Cell Biology 2026Brief Summary:The study by Karla Valdivieso and Tomaž ...

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Reposted by Karla Valdivieso

Iberoamerican ICSA @iberoicsa.bsky.social · 12/10/2026

BONUS: Hybrid Satellite Course! Interested in learning more about cellular senescence and aging? Join our hybrid course, "Biology of Senescence and Aging"! 🗓️ January 11–15, 2027 🌎 Online or in Mexico City 🗣️ Taught in Spanish 🔗 smb.org.mx/ibero-icsa-2...

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Reposted by Karla Valdivieso

Iberoamerican ICSA @iberoicsa.bsky.social · 12/10/2026

🎉 The wait is over! The FIRST in-person #IberoICSA meeting is happening in Mexico City! 🗓️ March 16–19, 2027 Join us as we bring together the Ibero-American and international cellular senescence community! 🔗 smb.org.mx/ibero-icsa-2...

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Karla Valdivieso @kvaldivieso.bsky.social · 31/08/2026

Our paper is out🎉 We show that clearing senescent cells after radiation exposure can improve tissue recovery and increase lifespan, but only when the timing is right. So glad to have worked alongside such brilliant scientists. #aging #senescence #cancer #mayo onlinelibrary.wiley.com/doi/10.1111/...

onlinelibrary.wiley.com

Timing‐Dependent Clearance of p16‐Positive Cells Mitigates Radiation‐Induced Accelerated Aging

Genotoxic stress induces a progressive accelerated aging-like phenotype driven by the delayed accumulation of p16Ink4a-positive senescent cells. Selective clearance of these cells improves healthspan...

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Reposted by Karla Valdivieso

LBI Trauma @lbitrauma.bsky.social · 31/12/2024

Congrats to Sara Kostrebic on earning her MSc! Her thesis 'Identifying Cellular Factors in Trauma-Induced Frailty,' explores how aging affects recovery from injury. She completed her work under the guidance of Karla Valdivieso @kvaldivieso.bsky.social, Mikolaj Ogrodnik, and Gordin Zupkovitz.

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