Reposted by Peter Adams
Nature research paper: Human-correlated genetic models identify precision therapy for liver cancer
go.nature.com/41qNkbs
go.nature.com
Human-correlated genetic models identify precision therapy for liver cancer - Nature
As proof of principle, an analysis using a suite of human-aligned immunocompetent mouse models of hepatocellular carcinoma identifies a promising therapeutic candidate, cladribine, which acts in a highly effective subtype-specific manner in combination with standard-of-care therapy.