iiinova — where your digital self keeps evolving

Karl Koehler @krkoehler.bsky.social · 07/11/2025

The latest story from my group. Working toward build regionally distinct skin and amnion piece by piece.

Reposted by Karl Koehler

the JID Journal @thejidjournal.bsky.social · 23/08/2025

📢 The September Issue of the JID is here! Explore the latest issue here: www.jidonline.org/current #DermatologyJournal #dermsky On the cover: A cross-section of a 146 day-old hair-bearing skin organoid derived from human pluripotent stem cells. @krkoehler.bsky.social @BostonChildrens.bsky.social

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Karl Koehler @krkoehler.bsky.social · 21/07/2025

I am moderating the upcoming ISSCR Digital Webinar: Modeling Human Neural Development and Disease with iPSCs. Join me to explore the latest science on neural development, disease mechanisms, and genetic variability from ISSCR 2025 Poster Award Winners. invt.io/1bxbs3ez8ty

invt.io

I'm moderating the upcoming ISSCR Digital Webinar. Join me!

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Karl Koehler @krkoehler.bsky.social · 20/12/2024

All #organoid enthusiasts, please consider joining us in Heidelberg, Germany, October 2025. My co-organizers, Meri Huch, @lancasterlab.bsky.social, Esther Schnapp, and I have assembled an excellent speaker list, with keynotes from Paola Arlotta and Matthias Lütolf. Hope to see you there!

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Reposted by Karl Koehler

Junyue Cao @junyuecao.bsky.social · 29/11/2024

Excited to share our work @science.org. led by our incredible @tommyz626.bsky.social at @rockefelleruniv.bsky.social! By profiling 21 million single cells across life stages, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific time windows!

tinyurl.com

A panoramic view of cell population dynamics in mammalian aging

To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...

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Karl Koehler @krkoehler.bsky.social · 25/11/2024

Posting one of my favorite #organoid images for #microscopymonday. A 100+ day-old skin organoid with emerging hair follicles (ECAD, cyan) and endothelial cells (CD31, red). See: www.nature.com/immersive/d4.... Credit: Jiyoon Lee and Matt Steinhart from our lab. #devbio #stemcells

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Reposted by Karl Koehler

Jens Puschhof @jenspuschhof.bsky.social · 24/11/2024

#Organoid research starter pack. I didn't find many researchers from the field yet, please comment/text me to be added! go.bsky.app/RmXgs6d

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Karl Koehler @krkoehler.bsky.social · 21/11/2024

Exciting to see the collection of HCA papers out this week in Nature. Honored to be in the mix with our collaboration with @mhaniffa.bsky.social and Sarah Teichmann on a fetal skin atlas. Bravo to Hudaa, Elena, and Bayanne et al, for pulling this study together. A tremendous effort! rdcu.be/d02Yx

rdcu.be

A prenatal skin atlas reveals immune regulation of human skin morphogenesis

Nature - A comprehensive multi-omics reference atlas of prenatal human skin shows that innate immune cells crosstalk with non-immune cells to perform pivotal roles in skin morphogenesis, including...

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Reposted by Karl Koehler

Nature Portfolio @natureportfolio.nature.com · 20/11/2024

A collection published across Nature Portfolio journals presents early draft maps of cells in the human body from the Human Cell Atlas initiative. The research leverages new data and analytical tools to aid our understanding of human health and disease at a cellular level. 🧪

go.nature.com

The Human Cell Atlas: towards a first draft atlas

In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.

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