iiinova — where your digital self keeps evolving

Reposted by Kristen Young

Sean Fanning @docfanning.bsky.social · 27/06/2025

Very proud of Sofia for successfully defending her Master’s thesis today!! She’s starting her PhD in biomedicine at UMiami next year. Can’t wait to see what she’ll accomplish! I’m a proud PI!

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Reposted by Kristen Young

Sean Fanning @docfanning.bsky.social · 09/05/2025

Congratulations to Sofia for graduating with her Masters degree! She the first Masters student to graduate from our lab! She did an impressive amount of work studying our new antiestrogens in breast cancer! She’s starting her PhD studies at UMiami in the fall, keep an eye on this rising star!

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Reposted by Kristen Young

Sean Fanning @docfanning.bsky.social · 28/04/2025

Come see Kristen Young present her poster at 9:00 this morning! She shows how inhibiting immunosuppressive paracrine signaling with an antiestrogen reinvigorates NK cells to improve anticancer activities in ER+ breast cancer cells! @kristen-young.bsky.social #AACR25

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Reposted by Kristen Young

Sean Fanning @docfanning.bsky.social · 26/02/2025

@kristen-young.bsky.social presenting her award winning presentation at the Cardinal Bernardin Cancer Research night!

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Reposted by Kristen Young

Sean Fanning @docfanning.bsky.social · 17/01/2025

Our latest paper harnesses the power of estrogen receptor to discover new therapeutic vulnerabilities in breast cancer. Here, we reveal a new link between ER and DKK1, an immunosuppressive glycoprotein, in drug-resistant cells and show its clinical significance. pubmed.ncbi.nlm.nih.gov/38978585/

pubmed.ncbi.nlm.nih.gov

Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S ESR1 Mutant Breast Cancer Cells - PubMed

Resistance to endocrine therapies remains a major clinical hurdle in breast cancer. Mutations to estrogen receptor alpha (ERα) arise after continued therapeutic pressure. Next generation selective est...

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Reposted by Kristen Young

Sean Fanning @docfanning.bsky.social · 12/12/2024

@kristen-young.bsky.social presenting her poster at SABCS! Sounds like she had quite the crowd! Just after the acceptance of her paper in Breast Cancer Research! Big week for Kristen and the Fanning Lab!

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Reposted by Kristen Young

Sean Fanning @docfanning.bsky.social · 04/12/2024

If you are going to the San Antonio Breast Cancer Symposium this year please check out Kristen's poster "A Novel SERM Reinvigorates Natural Killer Cells by Uniquely Downregulating DKK1 in Breast Cancer Cells" poster number P2-06-08 during poster session 2, 5:30-7:00 on 12/11.

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