iiinova — where your digital self keeps evolving

Petya Krasteva

@krastevalab.bsky.social

1.9K followers 2.2K following 40 posts

Structural biologist and microbiologist at the IECB, CNRS, Bordeaux. Loves her kiddos, homies, science and bacteria! www.krasteva-lab.com

Posts Replies Media

Petya Krasteva @krastevalab.bsky.social · 02/07/2025

When it's so hot that your car catches fire on the road and you almost explode a gas station🔥🔥🔥

130

Petya Krasteva @krastevalab.bsky.social · 15/02/2025

I am not a chemist and must be brain-dead after prolonged ogling of electron density clouds but how TF is this cellopentaose 🤔?

110

Petya Krasteva @krastevalab.bsky.social · 15/02/2025

And another one bites the flux 🤘🤘🤘! Molecular replacement was tricky mostly because of Alphafold lacking imagination 😅! Beautiful home source data at 1.9 Å courtesy again of Xtal master @bkauffmann.bsky.social at our @iecb.bsky.social

0211

Petya Krasteva @krastevalab.bsky.social · 12/02/2025

Has been a while since we bothered to set up crystal trays, cryo-EM got us so spoiled 😄.. Not bad data either, home source dataset at 1.7 Å courtesy of our Xtal guru @bkauffmann.bsky.social at our @iecb.bsky.social 🤓🙏💠..

1271

Petya Krasteva @krastevalab.bsky.social · 20/11/2024

Happy to share our 📖 chapter on bacterial cellulose secretion! It took too long in press so it doesn't include our latest work on pEtN-cellulose secretion (doi.org/10.1038/s414...), which settled many open questions but nevertheless, hope you enjoy the read 🤓! link.springer.com/chapter/10.1...

0186

Petya Krasteva @krastevalab.bsky.social · 20/11/2024

That's where all the (re)tardigrades are 😂😂😂

010

Petya Krasteva @krastevalab.bsky.social · 06/06/2024

The latest completed work from our ERC StG BioMatrix is now online 🤩🦠🧫🔬🧪🤓: mechanisms for c-di-GMP sensing and synthase activation by proxy, pEtN-transferase recruitment and polymer modification: www.biorxiv.org/content/10.1...

054

Petya Krasteva @krastevalab.bsky.social · 24/01/2024

Nice highlight of our recent research on intracellular scaffolds for bacterial cellulose secretion 😍😍😍🙏🙏🙏 Original works from my lab: Abidi et al. in Science Advances (2022, left) and Sana et al. in Current Biology (2023, right). www.cell.com/current-biol...

010

Petya Krasteva @krastevalab.bsky.social · 22/12/2023

Great work from my resident expert bug-natic @ThibGSana and my ERASMUS+ intern-turned-staff-scientist-for-summer-job Areti Notopoulou (now back in Greece) 🤩🤩🤩!!!

000

Petya Krasteva @krastevalab.bsky.social · 22/12/2023

Kicking off the winter with our latest paper on bacterial cellulose (BC) secretion 🤩🤩🤩!! Roles for BcsD/CesD beyond BC crystallinity and more dedicated intracellular BcsD-Proline rich partner scaffolds for cellulose secretion across Proteobacteria: www.cell.com/current-biol...

331

Petya Krasteva @krastevalab.bsky.social · 13/12/2023

120

Petya Krasteva @krastevalab.bsky.social · 29/11/2023

We showed that the crystallinity factor BcsD is driven into a 3D supramolecular scaffold by the Pro-rich BcsH, or cellulose complementing factor. These proteins were thought to drive periplasmic cellulose extrusion, yet we showed that they act inside-out to array the synthase terminal complexes.

100