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Konrad Kording

@kordinglab.bsky.social
15K followers 580 following 1.3K posts

@Penn Prof, deep learning, brains, #causality, rigor, neuromatch.io, Transdisciplinary optimist, Dad, Loves outdoors, 🦖 , c4r.io

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Reposted by Konrad Kording
Nicholdav @nicholdav.bsky.social · 04/10/2026
Writing something up, and reading this + re-reading Mensh & @kordinglab.bsky.social's: journals.plos.org/ploscompbiol... The new paper has steps to follow, helps my ADD brain. The older paper helps me keep my eyes on the prize. I feel like many researchers need these, like, now more than ever
journals.plos.org
Ten simple rules for structuring papers
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Konrad Kording @kordinglab.bsky.social · 29/09/2026
beautiful overview. The proliferation of "agency".
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Konrad Kording @kordinglab.bsky.social · 28/09/2026
The alignment argument is orthogonal to this. We like thermostats because they produce a joint system that obeys simple rules (its temperature is roughly constant, barring major perturbations). An "agentic AI" does not positively have this property. E.g. on temperature loss it may overreact.
static.klipy.com
Sygourney Weaver: Nuke From Orbit
ALT: Sygourney Weaver: Nuke From Orbit
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Konrad Kording @kordinglab.bsky.social · 28/09/2026
I can try. But really, like in many things philosophical, Stanford Encyclopedia is my starting point: plato.stanford.edu/entries/agen... Key concepts here are intentionality and causality.
plato.stanford.edu
Agency (Stanford Encyclopedia of Philosophy)
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Konrad Kording @kordinglab.bsky.social · 28/09/2026
Why does it imply agentivity to you. Imitating someone does not make you an agent in my book.
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Konrad Kording @kordinglab.bsky.social · 28/09/2026
Also for an llm to be a thermostat alignment first need to be solved
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Konrad Kording @kordinglab.bsky.social · 28/09/2026
the wording agency does have a tinge of that in English.
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Konrad Kording @kordinglab.bsky.social · 28/09/2026
Yes. RnN declare a thermostat an agent. Everything is. Normal english minimally demands goals/desires and the willingness to work towards them. And usually a lot more.
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Konrad Kording @kordinglab.bsky.social · 27/09/2026
But we did iterate to make the answers better. Which now *is* agentcy ;)
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Konrad Kording @kordinglab.bsky.social · 27/09/2026
Why on earth did we, as a field, allow the word "agent" to be used the way it currently is?
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Reposted by Konrad Kording
Blake Richards @tyrellturing.bsky.social · 23/09/2026
I’m beyond honoured to be named a 2026 @schmidtsciences.bsky.social Polymath. With US$2.5 million over five years, I’ll be able to pursue an interdisciplinary project to combine quantitative and qualitative data to better capture human neurodiversity. 🧠📈 www.schmidtsciences.org/2026-polymat...
schmidtsciences.org
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Konrad Kording @kordinglab.bsky.social · 16/09/2026
I did advocate for it. But I was very thankful that people like Ed and George did the outreach for this.
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Konrad Kording @kordinglab.bsky.social · 16/09/2026
Wait. I don't think I was on that one.
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Reposted by Konrad Kording
Patrick Mineault @patrickmineault.bsky.social · 14/09/2026
Are virtual flies playing Beat Saber? SM64? Doom? No. The new fly connectome is an incredible achievement! Less is going on in the sim videos than it seems. I'm stoked to see people engage with neuroscience though. My breakdown: www.neuroai.science/p/are-flies-...
neuroai.science
Are flies playing Beat Saber?
What a time to be alive!
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Konrad Kording @kordinglab.bsky.social · 11/09/2026
But you did convince me to rebrand to questionfirst.org ;)
questionfirst.org
Question First - Structure Research Projects, Papers, and Grants
Be clear about the question and logic before you start research. AI mentoring from research question to methods - for papers, grants, and pitches.
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Konrad Kording @kordinglab.bsky.social · 10/09/2026
Really just me seeing lots of bad science. And wanting to help students do better.
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Konrad Kording @kordinglab.bsky.social · 10/09/2026
No such interests
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Konrad Kording @kordinglab.bsky.social · 09/09/2026
Author of this webpage here. What are your thoughts?
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Konrad Kording @kordinglab.bsky.social · 09/09/2026
As it is a new term, try out (free) planyourscience.com which helps make sure that scientific projects end up awesome.
planyourscience.com
Scientific Paper Planner - AI-Powered Research Planning
Structure your scientific research with AI-powered guidance. From hypothesis to methodology, plan your research paper with intelligent mentoring.
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Konrad Kording @kordinglab.bsky.social · 08/09/2026
why? Time makes every behavior infinite dimensional no?
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Konrad Kording @kordinglab.bsky.social · 07/09/2026
I wrote a super dynamic AI/LLM explainer webpage. Not public yet (don't yet know if it would bankrupt me and having some other constraints). Anyone willing to give it a try and give me some feedback? Mostly looking for feedback from the non-experts. Chat me if interested.
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Konrad Kording @kordinglab.bsky.social · 07/09/2026
Cool cool. Let’s not obsess about dimensionality. Good motto in a 1/f world!
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Konrad Kording @kordinglab.bsky.social · 04/09/2026
This is cool. But why don't people know how to pour coffee? www.biorxiv.org/content/10.6... the paper asks how to pour a coffee and the answer is "not like this!"
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Konrad Kording @kordinglab.bsky.social · 28/08/2026
Full page figure for explainer in popular journal.
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Konrad Kording @kordinglab.bsky.social · 28/08/2026
Awesome! gd is tagged as technical term and I think is important for people who want to learn deeper about this. What would be the first to remove and simplify? I know it’s too complicated but it’s a bit of a tradeoff. Also, what can I read from you?
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Konrad Kording @kordinglab.bsky.social · 28/08/2026
I agree that is all subtle. But would you agree that there are still massive differences between a human agent and a 2026 ai „agent“?
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Konrad Kording @kordinglab.bsky.social · 27/08/2026
Using AI in neuroscience labs. Great article at @thetransmitter.bsky.social by @nicoschuck.bsky.social. www.thetransmitter.org/artificial-i...
thetransmitter.org
How, when and why to use agentic AI in our neuroscience labs
With agentic AI’s rapid infiltration into science, researchers need to develop AI use policies and practices.
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Reposted by Konrad Kording
Peter Tennant @pwgtennant.bsky.social · 27/08/2026
Does the new shingles vaccine (Shingrix) protect against cardiovascular disease (CVD)? Yes, according to a new 'natural experiment' study in @natmed.nature.com. But the truth is sadly far less convincing! Pull up a chair and let's examine another peer review failure in a Nature journal. 1/10 🧵
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Reposted by Konrad Kording
Community for Rigor @comm4rigor.bsky.social · 27/08/2026
🎉 We are excited to welcome Katie Corker as a featured speaker at C4R26! 💬 "Strengthening Rigor Through Open Research and Evaluation" 📅 September 29, 11:30 am ET 📍 Philadelphia, PA 🎟️ Free with RSVP 🔗 link in bio #Preprints #OpenScience #Science
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
Would love to see what you come up with!
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
I was pretty sure noone would see it!
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
Inner speech is really outside of the yellow box. Its about allowing tokens that the user does not see. While the yellow box just makes tokens.
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
You would (somewhat) open the yellow box? — that’s where much research is but it’s in a way subordinate to what happens outside the box.
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
That boat has sailed. Sorry. It would have been better but it won’t happen. People want to claim these worlds. They want to believe them!
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
There is a reason why we need purple!
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
What would you change
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Konrad Kording @kordinglab.bsky.social · 26/08/2026
In high dimensions there are saddles but “no” local minima.
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
And there you have it. The Old Recipe got extended with ‘inner speech’ + tools + agents + better evaluation into today's interactively ‘thinking’ machines. A great deal of the strengths and weaknesses of today's LLMs can be understood from these component ideas.
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
And all of this, is better with better “training“ goals. Wherever truth is defined, push towards this truth (D). And where it is not defined, use LLMs to check answers ("self evaluation", (E))
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
A third idea (C) for making answers, combine many components into "Agents", : coordinate component large language models (LLMs), memory, databases, and tools
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
A second idea (B) for making answers, tool use. Call programs like databases, internet search, calculators etc.
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
A first idea (A) for making answers, inner speech. Produce words that are just like a scratchpad which the user never sees.
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
The result of this are what is sometimes called large-scale "stochastic parrots". Very impressive text but often somewhat superficial. But these are the old LLMs (think 2022). Innovation was super fast since.
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
The thing that makes Neural networks so powerful is that there is a direct way (4) of improving them with examples and towards any definition of answer quality (training).
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
The real work is done by a core machine, the neural network which is used to generate one word at a time based on its inputs. The probability of each word depends on prior words. And words are chosen one by one according to those probabilities.
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
All that LLMs do is convert prompt words into answer words (1). And the old recipe does that with two goals, language imitation (2) and people's rating of answer quality (3). Answers are produced word by word using a neural network.
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
We will use everyday language where possible and mark technical terms in purple. Key is that modern LLMs have a component of making answers (in blue, called "inference") and a component of improving answers (red, called "training").
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
It will also be part of an upcoming manuscript. Optimized with Brett Mensh of optimizescience.com -- and work in progress. Feel free to give feedback.
optimizescience.com
Optimize Science – Science Consulting and Writing Support
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Konrad Kording @kordinglab.bsky.social · 25/08/2026
Thread. I have yet to see a proper explanation of how LLMs actually work that is targeted to an informed general audience. So here is an explainer that I put together along with Tim @countzerozzz (inspired by @CIFAR_News LMB discussions).
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Konrad Kording @kordinglab.bsky.social · 24/08/2026
bot!
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