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Dr Ksenia G. Kolobynina

@kkolobynina.bsky.social

154 followers 582 following 1 posts

Researcher in Cardoso lab at the Technical University Darmstadt, Germany Passionate about chromatin, epigenetics, DNA repair and aging Microscopy specialist She/her Opinions are my own

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Reposted by Dr Ksenia G. Kolobynina

FragileNucleosome @fnucleosome.bsky.social · 18/03/2026

We have another exciting #FragileNucleosome seminar for you next week! @sunil-k-pradhan.bsky.social and Genevieve Fourel will share their fascinating stories on chromatin and genome organization. Click here to register: us06web.zoom.us/webinar/regi...

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Reposted by Dr Ksenia G. Kolobynina

Sunil Kumar Pradhan @sunil-k-pradhan.bsky.social · 10/09/2025

Different perspectives on epigenetic dynamics and memory, especially before genome replication: We show H3K36me3 is dynamically enriched at pericentromeric heterochromatin (PCH) before its replication and erased after, tightly linking epigenetics and replication timing. doi.org/10.1038/s443...

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Reposted by Dr Ksenia G. Kolobynina

Sunil Kumar Pradhan @sunil-k-pradhan.bsky.social · 10/09/2025

To probe the role of H3K36me3 at PCH, we developed a new approach: ✨ Nanobody-mediated targeting of oncohistone H3.1 K36M directly to pericentromeric heterochromatin. This locally reduced H3K36me3 without altering other histone modifications, and elsewhere in the chromatin.

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Dr Ksenia G. Kolobynina @kkolobynina.bsky.social · 04/02/2025

Creative handcrafted version of the replication patterns observed in mouse ES cells: the nuclei with chromocenters (bright blue) and replication foci marked by EdU (red beads). It already made its way to a PhD graduation hat ☺️🧑‍🎓

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Reposted by Dr Ksenia G. Kolobynina

EMBL @embl.org · 30/01/2025

EMBL green news!! ♻️ Registrations are open for our first Sustainable Research Symposium – together, we can reduce ecological footprint and ensure the viability of scientific research. Join us to discuss and identify solutions for sustainable science: www.embl.org/about/info/s...

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