The NIH is asking for comments on their proposed changes to the NIH grant review process and its reporting to the institute’s leadership. Here my comments, feel free to adapt them: When considering… |...

Single-cell transcriptome profiles of Foxl1-lineage cells along the intestinal crypt-villus axis

Epigenetic adaptation of beta cells across lifespan and disease

The house mouse maintains constant telomere length throughout life

Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1

Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset - Nature Communications

Spark Therapeutics is laying off 337 people, more than half its workforce, starting in May

Single-cell multiome analysis supports α-to-β transdifferentiation in human pancreas

Targeting the NLRP3 inflammasome–IL-1β pathway in type 2 diabetes and obesity - Diabetologia

3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity

GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing

Metabolomic age (MileAge) predicts health and life span: A comparison of multiple machine learning algorithms

G6PC2 controls glucagon secretion by defining the set point for glucose in pancreatic α cells

Arctic tundra now emits planet-warming pollution, federal report finds