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KH

@khvmd.bsky.social
195 followers 160 following 672 posts

pwME since 2018 Veterinarian Pittsburgh, PA USA

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KH @khvmd.bsky.social · 12/06/2026
This paragraph hit me like a sledge hammer. I have never considered mitochondrial origin from bacteria as a reason for chronic immune activation. I mean mitochondria got scooped up and repurposed like 2 billion years ago, you would think our immune systems would consider them self at this point!
However, under persistent stress, these systems become overwhelmed, resulting in the damage and release of mitochondrial damage-associated molecular patterns (mtDAMPs), including mtDNA, mitochondrial double-stranded RNA (mtdsRNA), and lipids such as cardiolipin. Due to their bacterial origin, when exposed to the cytosol, these molecules are potent
immunostimulants, engaging pattern recognition receptors (PRRs), driving interferon and cytokine responses, and perpetuating systemic inflammation
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KH @khvmd.bsky.social · 06/06/2026
I’ve got the matching girl version!
Two brown tabby cats sleeping together in a cat tree bed.
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KH @khvmd.bsky.social · 23/03/2026
Aww! So sweet. Here’s my Ripley.
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KH @khvmd.bsky.social · 04/04/2025
I’ve got her twin!
A brown tabby cat looking into the camera.
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KH @khvmd.bsky.social · 09/02/2025
He doesn’t see the connection!
A Twitter exchange between Molly Jong-Fast and Elon Musk. 

Molly Jong-Fast @ @MollyJon...•14h X" I don't think the richest guy in the world should be cutting funding for cancer research.

Elon Musk 0 X @elonmusk
I'm not. Wtf are you talking about?

Molly Jong-Fast ©
@MollyJongFast
The Trump administration is cutting billions of dollars in biomedical research funding, alarming academic leaders who said it would imperil their universities and medical centers...
NIH cuts billions of dollars in biomedical funding, effective i...
From washingtonnost.com
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KH @khvmd.bsky.social · 07/02/2025
@davetuller1.bsky.social @tomkindlon.bsky.social @naomidharvey.bsky.social
I recently saw a new newsletter from Terra Biological entitled Oxaloacetate CFS. 
I emailed them about using the term CFS. Suggesting that it was outdated, inaccurate, fraught with a history of harm to pwME, and in no small part responsible for the systemic failure of governments, medical institutions, research funding, poor research based on vague criteria, psychologizing, denial of benefits, dismissal and gaslighting of patients for decades. 
I thought they should replace CFS with ME or at least ME/CFS. 
I have read many articles over the years spelling out the history of harm done by the CFS nomenclature and its downstream effects on every aspect of the science, medical and social support for pwME.
I was asked to provide links for their review, but I am finding that I don’t have the energy to track them down. I was wondering if anybody could point me towards such articles so that I may pass them along?
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KH @khvmd.bsky.social · 24/11/2024
I’ve been thinking a lot about the ME Association chairman’s snarky opinion letter and this is my response.
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KH @khvmd.bsky.social · 22/10/2024
Ripley is named after Ellen Ripley from Alien. Aeryn is named after Aeryn Sun from Farscape. Strong, smart, capable ladies all!
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KH @khvmd.bsky.social · 22/10/2024
Everyone’s cats are so beautiful! 💕. These are my girls Ripley and Aeryn.
Two female brown tabby cats sitting by a window in the sun.
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