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Katrina Paras

@katrinaparas.bsky.social

41 followers 38 following 1 posts

Metabolomics Staff Scientist at Sanford Burnham Prebys | PhD Weill Cornell/MSKCC in the Finley Lab | UCLA alum

Posts Replies Media

Reposted by Katrina Paras

Ben Jackson @btjackson.bsky.social · 28/04/2025

I'm excited to share our latest story from the @lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/

rdcu.be

Intracellular metabolic gradients dictate dependence on exogenous pyruvate

Nature Metabolism - Jackson et al. provide insight into how metabolic adaptations that accompany cell state transitions drive reliance on exogenous nutrient availability, focusing on pyruvate as a...

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Katrina Paras @katrinaparas.bsky.social · 20/01/2025

Thrilled that my thesis work in @lydiafinley.bsky.social's lab is out in the world! We found that methotrexate targets a specific metabolic vulnerability in a particularly aggressive form of pediatric rhabdomyosarcoma. Thank you to everyone who contributed to this project over the years!

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Reposted by Katrina Paras

Lydia Finley @lydiafinley.bsky.social · 20/01/2025

Our latest preprint identifies (targetable!) metabolic programs intrinsic to different cancer cell states in rhabdomyosarcoma, out just in time for @katrinaparas.bsky.social's thesis defense tomorrow!

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