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Reposted by Karthik's Host-patho lab, India

Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 01/10/2026

Our new study in #JournalofExtracellularVesicles @isev.org shows that host microvesicles carrying pneumolysin remain membrane-active and damage recipient cells beyond canonical pore formation. Read on the mechanism: doi.org/10.1002/jev2... @isev.org #ExtracellularVesicles #Pneumolysin #HostPathogen

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 01/10/2026

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 24/09/2026

Latest study accepted in #JEV @isev.org Imagine your cells' own communication weaponized against you. We discovered bacterial toxins hijack extracellular vesicles to deliver a completely unexpected attack-membrane fusion. @tomdriekdonks.bsky.social @janlotvall.bsky.social @kennethwitwer.bsky.social

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 17/06/2026

Our new paper in @mbio.bsky.social 🦠What can a cancer drug teach us about bacterial cell?Sorafenib, an FDA-approved anticancer drug, kills S. pneumoniae by targeting cell division kinase StkP. @microbiologysociety.org #Microbiology #AntimicrobialResistance #DrugRepurposing 📖 doi.org/10.1128/mbio...

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 04/06/2026

Honored to be inducted as an Executive Board Member of the Indian Society for Extracellular Vesicles (InSEV). This reflects collective efforts of my Host-Pathogen Lab, RGCB, for outstanding contributions. insev.in/board-members/ @isev.org @snevresearch.bsky.social #ExtracellularVesicles

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 11/05/2026

"Science hit different today. 🔬 Students packed our Extracellular Vesicles stall at #NationalTechnologyDay at BRIC-RGCB- curious, excited, and full of questions.That's #PrecisionMedicine 🧪 right there. 🧫 @isev.org @snevresearch.bsky.social #ScienceOutreach #EVs #PrecisionMedicine #Biotechnology

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 23/04/2026

Two bright minds, one proud lab moment. 🧪✨ From our Host–Pathogen Lab to bigger journeys-Ajay heading to UGA 🇺🇸, Anandhu to ICAR-NIVEDI 🇮🇳. Thoughtful mementos, lasting memories.Keep questioning, keep discovering. 🚀 @universityofga.bsky.social @asm.org @microbiologysociety.org @science.org @nature.com

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Reposted by Karthik's Host-patho lab, India

Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 04/04/2026

Honored to deliver an invited talk at #EVOLVE2026 (InSEV) at RGCB on our work in EVs, pneumococcal pathogenesis, and host immunity. Great to reconnect with colleagues and students, and grateful to be inducted into the InSEV Executive Committee. Excited to help grow #EV research in India!

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 04/04/2026

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Reposted by Karthik's Host-patho lab, India

Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 10/03/2026

Can bacterial toxins mimic SNARE-like membrane fusion? Our Latest preprint shows EV-bound pneumolysin engages membrane lipids & destabilizes cell membrane in non canonical toxin activity. www.biorxiv.org/content/10.6... #ExtracellularVesicles #BacterialToxins @isev.org @biorxivpreprint.bsky.social

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 10/03/2026

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 24/01/2026

🔬 Hiring: Project Technical Support–III at BRIC-RGCB Join the Host–Pathogen Lab for an ICMR-funded project on Extracellular Vesicles & Bacterial Pneumonia. 🔗 lnkd.in/g3xMhcPP #ScienceJobs #Extracellularvesicles #HostPathogen #AcademicSky

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 11/12/2025

Our lab 🧫 turns 5! 🎉 Our mission: investigating pneumococcal infections via 3 strategic ways: Extracellular Vesicles, AMR drug repurposing, immune profiling. ✅ 4 Projects ✅ 3+ Publications ✅ Training 4 PhD students, 20+ MSc Trainees Thanks to my brilliant team-past & present for the dedication!

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 07/11/2025

Such a fantastic meeting @isev.org EVs in Immunity, Athens, Greece. Great to present our work and meet the international EV community.

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 02/11/2025

Excited to talk about the lab's latest research on extracellular vesicles in @isev.org EVs in Immunity, Athens next week. https://www.isev.org/evs-in-immunity #EVsInImmunity #ISEV

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 07/10/2025

I’m pleased to share that I’ve been inducted into the Editorial Board of Microbiology Spectrum, American Society for Microbiology. Looking fwd to work with journal to advancing excellence in microbiological research and publishing. journals.asm.org/journal/spec... #Microbiology #ASM #Science

journals.asm.org

Microbiology Spectrum Reviewing Editors

Current Microbiology Spectrum Reviewing Editors

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 02/09/2025

Had an incredibly enriching four days at the RGCB Research Conference in beautiful Munnar! The scientific sessions were cutting-edge and a true honor to hear from Nobel laurate, Prof. Morten Meldal. It was also great to catch up with Dhiraj Kumar from ICGEB and Puran Sijwali from CCMB Hyderabad.

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 15/08/2025

🚨New Preprint! Excited to share our latest work on tackling Streptococcus pneumoniae, a major cause of pneumonia and meningitis worldwide - a WHO priority pathogen. 📄 Read doi.org/10.1101/2025... #AntibioticResistance #DrugRepurposing #PneumoniaResearch #StreptococcusPneumoniae #Antivirulence

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 07/07/2025

Very cool indeed! The mechanism of NET-thrombin binding and the potential for antisense LNA therapy opens up exciting avenues for treating dangerous clots. Great work highlighted here!

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 22/06/2025

Celebrating graduation of two MSc thesis students, Sudarshan and Sreerenjini from the lab. Sudarshan worked on screening virulence inhibitors while Sreerenjini worked on Extracellular vesicles Humbled to receive the "Best Guru" memento from these amazing young scientists. Go conquer the world!

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 17/05/2025

A national symposium was organized to honor superannuating scientists, Dr. Moinak and Dr. Soniya from Rajiv Gandhi Centre for Biotechnology. They described their journey inspirations followed by scientific poster sessions. Aswathy presented her existing findings in her poster gathering wide interest

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 25/12/2024

Lithocolic acid identified as key metabolite promoting longevity during CR.

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 24/11/2024

Pleasure to share our latest story from my laboratory on bacterial virulence inhibitors at the International AMR symposium #ALARM2024 at Amrita School of Biotechnology. Special thanks Dr. Bipin and @Geetha Kumar. Congrats to my student, Joel for winning the best poster award 👏 @nizet.bsky.social

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Karthik's Host-patho lab, India @karthiks-lab.bsky.social · 20/11/2024

Hello bluesky! Thus is our first tweet here. We are a curious bunch of scientists working on infection biology at Rajiv Gandhi Centre for Biotechnology, India. Look forward to connecting with fellow scientists. Please like and message so I can connect.

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