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Karson Chrispens

@karsonchrispens.bsky.social

48 followers 171 following 3 posts

UCSF Biophysics PhD Student. Looking at proteins @fraserlab.bsky.social. Pronouns he/him.

Posts Replies Media

Reposted by Karson Chrispens

Stephanie Wankowicz @stephanieaw.bsky.social · 15/06/2026

Excited to present sampleworks: a modular platform for generating biomolecular conformational ensembles by coupling AI structure predictors to experimental data. Our first publication of @diffuseproject.bsky.social, led by @karsonchrispens.bsky.social + Marcus Collins. thestacks.org/publications...

thestacks.org

sampleworks: A Modular Platform for Experimentally Guided Biomolecular Ensemble Generation

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Reposted by Karson Chrispens

Stephanie Wankowicz @stephanieaw.bsky.social · 12/03/2026

Excited to share Sampleworks led by @karsonchrispens.bsky.social with @diffuseproject.bsky.social. It's a modular framework connecting structure predictors to experimental data and guidance methods. Swap predictors or guidance methods. All open and made to be built upon. t.co/fvNHH3gfVu

t.co

https://diffuse.science/posts/sampleworks/

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Karson Chrispens @karsonchrispens.bsky.social · 20/06/2025

Hi bluesky scientists! Recently, @stephanieaw.bsky.social @fraserlab.com held a workshop at UCSF to discuss methods for modeling heterogeneity in structural biology (conformationalensembles.github.io).

prereview.org

PREreview of “Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction”

Authored by Karson Chrispens and 2 other authors

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