Nature Communications - During development of eutherian females, one of the X-chromosomes is silenced. Here, authors show that alleles on the inactive X-chromosome are dynamically expressed along...

The field of brain organoids has experienced a period of rapid and transformative growth, enabling researchers to investigate complex human biological…

Tomohisa Toda, Professor für neurale Epigenomik an der Friedrich-Alexander-Universität Erlangen-Nürnberg, erhält den Joseph-Altman-Award.

Periventricular heterotopia (PH) is associated with neurodevelopmental delay. Here authors report patient-derived organoids with FAT4 and DCHS1 mutations mimic PH features, showing hyperactivity, syna...