Reposted by Jess Stock
🧵 Out today in Nature Communications! How did an ancient reshuffling of the genome shape 3D genome architecture and gene regulation in squid, cuttlefish & octopus? 🦑🐙
We combined Micro-C, RNA-seq & ATAC-seq across species, developmental stages & tissues.
doi.org/10.1038/s41467-026-77625-7
doi.org
Genome reorganisation and expansion shape 3D genome architecture and define a distinct regulatory landscape in coleoid cephalopods - Nature Communications
How genome organisation contributes to the evolution of biological complexity is poorly understood. This study shows evolutionary changes in 3D genome architecture rewires gene regulation in coleoid c...
