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Joyce Valadares

@joycevaladares.bsky.social

26 followers 40 following 1 posts

PhD researcher at the MRC MBU, University of Cambridge, studying cardiac metabolism during IR injury.

Posts Replies Media

Reposted by Joyce Valadares

Mike Murphy @mitoredox.bsky.social · 01/05/2026

Congrats to Laura Pala and Hiran Prag on their new paper in Cardiovascular Research. doi.org/10.1093/cvr/...

doi.org

Mitochondrial succinate transport is required for cardiac ischaemia/reperfusion injury

AbstractAims. Succinate accumulates significantly during myocardial ischaemia, and its rapid oxidation upon reperfusion is a critical driver of ischaemia/r

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Joyce Valadares @joycevaladares.bsky.social · 20/10/2025

Excited to share that at the annual MRC MBU symposium I was awarded best poster prize for my PhD project on Succinate Metabolism in Cardiac Ischemia/ Reperfusion Injury! Thanks to my lab, collaborators, and my PI Mike Murphy. @mitoredox.bsky.social

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Reposted by Joyce Valadares

Mike Murphy @mitoredox.bsky.social · 19/02/2025

Great to see paper from Alva Casey out today in Nature Metabolism - from her PhD. Well done Alva! doi.org/10.1038/s422...

doi.org

Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation - Nature Metabolism

Casey et al. explore the basic mechanisms of mitochondrial superoxide production and its impact on interleukin-1β production in LPS-treated macrophages.

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