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Journal of Comparative Effectiveness Research

@journal-cer.bsky.social
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The latest CER, RWE & HEOR for patients, researchers, policy makers & all stakeholders | IF: 2.8 | MEDLINE-indexed | from Becaris Publishing

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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 31/07/2026
📢New article alert Meta-Analysis: Systematic review & network meta-analysis of the efficacy, safety & tolerability of xanomeline plus trospium chloride compared with eight oral antipsychotics for the acute treatment of schizophrenia 🔗 becarispublishing.com/doi/10.57264... #OpenAccess #JCER
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Systematic review and network meta-analysis of the efficacy, safety and tolerability of xanomeline plus trospium chloride compared with eight oral antipsychotics for the acute treatment of schizophren...
Aim: The recently approved first-in-class combination therapy xanomeline/trospium chloride (KarXT) demonstrated superiority over placebo in three randomized controlled trials (RCTs) of adults with sch...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 30/07/2026
📢New article alert Research Article: Effect of dose tapering policy on the prescription of advanced therapy for rheumatoid arthritis: a retrospective analysis of clinical and cost outcomes in Taiwan 🔗 becarispublishing.com/doi/10.57264... #OpenAccess #JCER #RheumatoidArthritis #HealthPolicy #RWE
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Effect of dose tapering policy on the prescription of advanced therapy for rheumatoid arthritis: a retrospective analysis of clinical and cost outcomes in Taiwan
Aim: To evaluate the impact of the Taiwan National Health Insurance program policy for advanced rheumatoid arthritis (aRA) therapies on treatment prescription patterns and costs in patients with rheum...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 30/07/2026
📢New article alert Mortality risk estimation for autistic older adults: comparing novel machine-learning derived weights vs standard weights for the Charlson Comorbidity Index 🔗 becarispublishing.com/doi/10.57264... #OpenAccess #JCER #Autism #MachineLearning #RealWorldEvidence #HealthOutcomes
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Mortality risk estimation for autistic older adults: comparing novel machine-learning derived weights versus standard weights for the Charlson Comorbidity Index
Aim: We aimed to compare Quan and colleagues (2011) established weights for the Charlson Comorbidity Index (CCI) conditions to autism-specific weights for predicting mortality risk in autistic older a...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 24/07/2026
📢New article alert New Research Article: "Transparency in positive airway pressure therapy trials: an evaluation of reporting quality" 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #ClinicalTrials #ResearchTransparency #ResearchIntegrity #SleepMedicine
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Transparency in positive airway pressure therapy trials: an evaluation of reporting quality
Aim: Accurate and detailed reporting of nonpharmacological interventions such as positive airway pressure (PAP) therapy is essential for reproducibility, yet previous research shows frequent reporting...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 22/07/2026
📢New article alert: Clinical effectiveness of a digitally delivered balance program for older adults: a nonrandomized controlled trial becarispublishing.com/doi/10.57264...
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Clinical effectiveness of a digitally delivered balance program for older adults: a nonrandomized controlled trial
Aim: To evaluate the clinical effectiveness of a digitally delivered balance program relative to an attention-control comparison group in older adults at risk for falls. Materials & methods: This ...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 11/02/2026
📢New article alert Treatment burden and healthcare resource utilization in patients with chronic rhinosinusitis with nasal polyps who did or did not undergo functional endoscopic sinus surgery: a US real-world retrospective cohort study 🔗 becarispublishing.com/doi/10.57264... #OpenAccess #JCER
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Treatment burden and healthcare resource utilization in patients with chronic rhinosinusitis with nasal polyps who did or did not undergo functional endoscopic sinus surgery: a US real-world retrospec...
Aim: To compare oral corticosteroid (OCS) burden and healthcare resource utilization (HCRU) in patients with chronic rhinosinusitis with nasal polyps undergoing functional endoscopic sinus surgery (FE...
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The Evidence Base @theevidencebase.bsky.social · 10/02/2026
Why misaligned evidence strategies delay #PatientAccess to medicines | Becaris Publishing becarispublishing.com/digital-cont...
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Why misaligned evidence strategies delay patient access to medicines | Becaris Publishing
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The Evidence Base @theevidencebase.bsky.social · 05/02/2026
#RareDisease outcome assessment under #EUHTA and #JointClinicalAssessment | Becaris Publishing becarispublishing.com/digital-cont...
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Rare disease outcome assessment under EU HTA and joint clinical assessment | Becaris Publishing
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The Evidence Base @theevidencebase.bsky.social · 05/02/2026
Hot off the press: Part one of our pick of articles within #HTA and #RWE published in January 2026 | Becaris Publishing becarispublishing.com/digital-cont...
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Hot off the press: Part one of our pick of articles within HTA and RWE published in January 2026 | Becaris Publishing
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 04/02/2026
📢New article alert New Perspective article on "Sieving for gold: external comparator studies to prioritize drugs for late-stage clinical trial" 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #TrialMethodology #RealWorldEvidence #RWE
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Sieving for gold: external comparator studies to prioritize drugs for late-stage clinical trial
External comparator (EC) studies can improve identification of compounds with the most promising performance in pre-pivotal single-arm trials (SAT). As SAT output lacks comparative insights, EC studie...
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The Evidence Base @theevidencebase.bsky.social · 04/02/2026
Head-to-head real-world study reports overall survival advantage with apalutamide compared with darolutamide in metastatic castration-sensitive #ProstateCancer | Becaris Publishing becarispublishing.com/digital-cont...
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Head-to-head real-world study reports overall survival advantage with apalutamide compared with darolutamide in metastatic castration-sensitive prostate cancer | Becaris Publishing
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The Evidence Base @theevidencebase.bsky.social · 02/02/2026
#IndustryUpdate tracker: January 2026 | Becaris Publishing becarispublishing.com/digital-cont...
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Industry update tracker: January 2026 | Becaris Publishing
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The Evidence Base @theevidencebase.bsky.social · 02/02/2026
Patient roles and expectations in effective #HTA engagement | Becaris Publishing becarispublishing.com/digital-cont...
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Patient roles and expectations in effective HTA engagement | Becaris Publishing
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 30/01/2026
📢New article alert New Research Article on “Indirect comparisons of tucatinib in combination with trastuzumab for patients with previously treated HER2–positive metastatic colorectal cancer”. 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #ColorectalCancer #Oncology #ITC
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Indirect comparisons of tucatinib in combination with trastuzumab for patients with previously treated HER2–positive metastatic colorectal cancer
Aim: In the single-arm MOUNTAINEER trial (NCT03043313) tucatinib in combination with trastuzumab showed an objective response rate (ORR) of 39.3% in patients with previously treated, HER2+ unresectabl...
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The Evidence Base @theevidencebase.bsky.social · 29/01/2026
#CMS announces drugs selected for third cycle of #Medicare #DrugPrice negotiations | Becaris Publishing becarispublishing.com/digital-cont...
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CMS announces drugs selected for third cycle of Medicare drug price negotiations | Becaris Publishing
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 29/01/2026
📢New Research Article alert "Acthar Gel versus standard of care for adults with proteinuria in nephrotic syndrome due to focal segmental glomerulosclerosis: cost-per-response analysis from the US healthcare perspective" 🔗 becarispublishing.com/doi/10.57264... #OpenAccess #JCER #KidneyDisease
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Acthar Gel versus standard of care for adults with proteinuria in nephrotic syndrome due to focal segmental glomerulosclerosis: cost-per-response analysis from the US healthcare perspective
Aim: Proteinuria poses a significant challenge in focal segmental glomerulosclerosis (FSGS), particularly when resistant to standard treatments. Acthar® Gel, a Food and Drug Administration (FDA)-appro...
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The Evidence Base @theevidencebase.bsky.social · 29/01/2026
Modeling #caregiver quality of life in #HTA: Why economic models struggle to reflect lived experience | Becaris Publishing becarispublishing.com/digital-cont...
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Modeling caregiver quality of life in HTA: Why economic models struggle to reflect lived experience | Becaris Publishing
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 29/01/2026
📢New article alert New Short Report on "First-line tumor necrosis factor inhibitor versus abatacept treatment choice in real-world patients with anticitrullinated protein antibody- and rheumatoid factor-positive rheumatoid arthritis". 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess
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First-line tumor necrosis factor inhibitor versus abatacept treatment choice in real-world patients with anticitrullinated protein antibody- and rheumatoid factor-positive rheumatoid arthritis
Aim: To compare characteristics of patients with anticitrullinated protein antibody-positive (ACPA+) and rheumatoid factor-positive (RF+) rheumatoid arthritis (RA) who initiated abatacept or a tumor n...
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The Evidence Base @theevidencebase.bsky.social · 28/01/2026
New in the Journal of Comparative Effectiveness Research: Video Snapshots | Becaris Publishing becarispublishing.com/digital-cont...
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New in the Journal of Comparative Effectiveness Research: Video Snapshots | Becaris Publishing
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The Evidence Base @theevidencebase.bsky.social · 27/01/2026
FDA draft guidance clarifies use of Bayesian methods in #ClinicalTrials | Becaris Publishing becarispublishing.com/digital-cont...
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FDA draft guidance clarifies use of Bayesian methods in clinical trials | Becaris Publishing
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 26/01/2026
📢New article alert New Review article on “Reshaping the cardiovascular continuum in the management of arterial and venous cardiovascular disease: a narrative review”. 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #CardiovascularDisease #Prevention #IntegratedCare
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Reshaping the cardiovascular continuum in the management of arterial and venous cardiovascular disease: a narrative review
The prevalence of cardiovascular disease (CVaD) is expected to double in the next 25 years, fueled by increasing prevalence of diabetes mellitus, obesity and hypertension. Cardiovascular–kidney–m...
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The Evidence Base @theevidencebase.bsky.social · 26/01/2026
Health Canada opens consultation on draft guidance for decentralized clinical trials | Becaris Publishing becarispublishing.com/digital-cont...
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Health Canada opens consultation on draft guidance for decentralized clinical trials | Becaris Publishing
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 26/01/2026
📢New article alert New Research Article on “The impact of socioeconomic crisis on cancer patient outcomes in Lebanon, 2018–2020”. 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #Oncology #GlobalHealth #HealthEquity #HealthPolicy
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The impact of socioeconomic crisis on cancer patient outcomes in Lebanon, 2018–2020
Aim: The goal of this study was to assess the impact of economic and social crisis on access to cancer care in Lebanon. Materials & methods: A cancer Drug Access Program in Lebanon was launched, c...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 23/01/2026
📢New article alert New Short Report on "Comparison of deep prostate-specific antigen response in Black patients with metastatic castration-sensitive prostate cancer initiated on apalutamide or enzalutamide". 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #ProstateCancer #RWE
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Comparison of deep prostate-specific antigen response in Black patients with metastatic castration-sensitive prostate cancer initiated on apalutamide or enzalutamide
Aim: There is limited real-world evidence about prostate-specific antigen (PSA) response to androgen receptor pathway inhibitor treatment in Black patients with metastatic castration-sensitive prostat...
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The Evidence Base @theevidencebase.bsky.social · 22/01/2026
ISPOR’s 2026–2027 Top HEOR Trends highlight the growing role of #AI, #RealWorldEvidence, and #ValueBasedHealthcare | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 21/01/2026
EU HTA Regulation: One year on, what has changed for patient involvement? | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 19/01/2026
Ro and Amgen to examine barriers to #GLP-1 access in #obesity care using #RealWorldData | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 16/01/2026
Trump administration announces “Great Healthcare Plan” proposal centered on legislative action to secure #most-favored-nation #DrugPricing | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 16/01/2026
EMA and FDA align on principles for use of #AI across the medicines lifecycle | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 15/01/2026
#HealthDataResearchService: how the UK plans to enable secure, large-scale #HealthData research | Becaris Publishing becarispublishing.com/digital-cont...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 14/01/2026
📢New article alert New Review article on "The importance and challenge of comparing stroke care, utilization and outcomes in Medicare Advantage and Fee-for-Service Medicare: a narrative review and vision for the future". 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #Stroke
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 14/01/2026
📢New article alert New Meta-Analysis: "Effectiveness and safety of therapies for patients with opioid use disorder: a systematic review and network meta-analysis" 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #OpioidUseDisorder #NetworkMetaAnalysis #PublicHealth
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The Evidence Base @theevidencebase.bsky.social · 14/01/2026
ConcertAI and Foundation Medicine to link real-world #ClinicalData with #genomics to advance #oncology research | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 14/01/2026
GeneDx and Komodo Health partner to link #Genomic and #RealWorldData for #RareDisease evidence generation | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 14/01/2026
Hot off the press: Part two of our pick of articles within #HTA and #RWE published in December 2025 | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 13/01/2026
Looking ahead to the World EPA Congress 2026 | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 12/01/2026
Hot off the press: Part one of our pick of articles within #HTA and #RWE published in December 2025 | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 12/01/2026
#RWE and #HTA – a snapshot of recent developments with Sreeram Ramagopalan: October–December 2025 | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 12/01/2026
Connecting real-world datasets to provide deeper insights into the patient journey | @cardinalhealth.bsky.social becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 09/01/2026
Patti's People - Patti Peeples speaks with Paul Scuffham | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 09/01/2026
NIH sets out framework to embed public partnership across #ClinicalResearch | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 09/01/2026
Thermo Fisher Scientific enrolls first patient in new registry, marking launch of its PPD™ CorEvitas™ #Obesity Registry | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 07/01/2026
RWE4Decisions Symposium 2025: Practical pathways for using RWD in HTA and reimbursement | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 07/01/2026
Lessons from a pilot study on AI coding and analysis of qualitative patient data | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 06/01/2026
Industry news round-up: updates from December 2025 | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 06/01/2026
#FDA guidance on #ClinicalTrial participation highlights eligibility reform and expanded access | Becaris Publishing becarispublishing.com/digital-cont...
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Journal of Comparative Effectiveness Research @journal-cer.bsky.social · 06/01/2026
📢New article alert New Meta-Analysis on "Population-adjusted network meta-analyses provide new insights into the efficacy of treatment alternatives for metastatic castration-sensitive prostate cancer". 🔗Read here: becarispublishing.com/doi/10.57264... #OpenAccess #JCER #NMA #ProstateCancer
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The Evidence Base @theevidencebase.bsky.social · 06/01/2026
What makes evidence matter? Examining the real-world evidence decision paradox | becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 06/01/2026
VIDEO: Most-favored nation pricing: Updates and strategic insights from Tim Wright, Genesis Research Group | Becaris Publishing becarispublishing.com/digital-cont...
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The Evidence Base @theevidencebase.bsky.social · 19/12/2025
Lessons from a pilot study on #AI coding and analysis of qualitative patient data | @thermofishersci.bsky.social becarispublishing.com/digital-cont...
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Lessons from a pilot study on AI coding and analysis of qualitative patient data | Becaris Publishing
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