iiinova — where your digital self keeps evolving

Joe Matthews @josephmatthews.bsky.social · 27/10/2025

Two interesting metabolic health studies published this month! 👉🏽 Effect of sweeteners on weight management and gut microbiota composition in individuals with overweight or obesity: the SWEET study 🔘 ~1.6 kg improvement in across all participants 🔘 ~3.8 kg improvement in the highest adherence group

Graph showing the difference in weight loss maintenance between sweetener and sugar groups. The sweetener group regained significantly less body weight over 12-months.

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Joe Matthews @josephmatthews.bsky.social · 03/10/2025

Okay I’m officially done on X/Twitter. In dire need of a healthy science community with people posting interesting takes on research. Where are my nutrition and metabolism people…? 🍎

media.tenor.com

a man drinking from a can that says science on it

ALT: a man drinking from a can that says science on it

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Joe Matthews @josephmatthews.bsky.social · 02/10/2025

In my latest Substack, I cover the science of how biology fights back after weight loss: 🔘 Metabolic adaptation (or not…) 🔘 Hunger hormone shifts 🔘 Heightened reward sensitivity to food cues 🔘 A potential “memory” of obesity in fat cells 🔗 josephmatthewsphd.substack.com/p/the-bigges...

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Joe Matthews @josephmatthews.bsky.social · 20/07/2025

What is dietary protein quality? New paper in the Journal of Nutrition. My first, first-author paper since joining UAMS. Dietary protein quality is the ability of a protein source to provide bioavailable essential amino acids (EAAs). But what affects this…?👇🏽 🔗 shorturl.at/elQLE

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Joe Matthews @josephmatthews.bsky.social · 04/07/2025

One year in Little Rock, Arkansas! 🇺🇸 It's hard to believe a year has passed already. Looking forward to spending more time in The Natural State!

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Michele Zanini @mzaniniphysiology.bsky.social · 02/03/2025

🚨 New study 🚨 The biggest project of my PhD is out in MSSE journal. 🔑 findings: Strength training improves running economy durability & high-intensity performance following prolonged running. 🙏🏼 R. Blagrove and J. Folland for the SUPERvision on this. 🔗 journals.lww.com/acsm-msse/ab... 🧵 1/10

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Joe Matthews @josephmatthews.bsky.social · 02/03/2025

Do carnosine and beta-alanine (BA) offer benefits beyond enhancing exercise performance? Yes and no 🤔 📰 Thread with summary of research and links to open-access papers 👇🏽

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The Journal of Physiology @jphysiol.bsky.social · 17/01/2025

Christopher W. Sundberg et al. investigated the cumulative effects of H+ and Pi on #force and #power of skeletal muscle fibres from young and older adults 💥🔋 📜 Read the #Research here: buff.ly/40BBX02

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Joe Matthews @josephmatthews.bsky.social · 08/01/2025

The latest publication from our lab at UAMS 👇🏼

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Joe Matthews @josephmatthews.bsky.social · 04/01/2025

2024 Protein Nutrition Review! What's new in dietary protein? 🥩🫘 A brief overview of SEVEN insightful muscle protein synthesis (MPS) studies (references and links included) 👇🏽

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Joe Matthews @josephmatthews.bsky.social · 27/12/2024

New study suggests a higher plant-to-animal protein ratio is associated with lower risks of CVD and CAD. I find these studies challenging to interpret given the underlying data used in the analyses: "A food frequency questionnaire was administered every 4 years to determine dietary intake"

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Joe Matthews @josephmatthews.bsky.social · 02/12/2024

“Cellular engineering has already allowed us to rebuild parts of humans with re-engineered cells. As our understanding of this arena grows, new medical and ethical conundrums will arise, intensifying and challenging the basic definition of who we are, and how much we wish to change ourselves.”

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Joe Matthews @josephmatthews.bsky.social · 02/12/2024

Finally finished this masterpiece from @DrSidMukherjee - a beautiful story on the past, present, and future of cell biology and its role in health and disease 🦠🧬🧫

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Joe Matthews @josephmatthews.bsky.social · 28/11/2024

Happy Thanksgiving to all my friends in the US! 🦃

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Joe Matthews @josephmatthews.bsky.social · 27/11/2024

Biomedical researchers share their priorities for the U.S. ahead of incoming administration: ⚪ Support education and reproductive care ⚪ Embrance medical AI ⚪ Protect patients ⚪ Prepare for the next pandemic ⚪ Be smarter with antibiotics www.nature.com/articles/d41...

nature.com

Hopes, fears and uncertainty: life scientists react to Trump’s election victory

Leading biomedical researchers outline their priorities for the incoming administration.

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Joe Matthews @josephmatthews.bsky.social · 27/11/2024

Hugely relatable scene in the new film Joy on Netflix

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Joe Matthews @josephmatthews.bsky.social · 21/11/2024

The Consensus app is a game-changer for scientific searches and writing. It generates research summaries and links to peer-reviewed articles (also available as an app via Chat GPT) 👇🏽

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John Speakman @johnspeakman4.bsky.social · 21/11/2024

Views about the causes of obesity have polarised. Characterised by low carb and energy balance models. Last year NovoNordisk invited the protagonists of these models to Copenhagen to discuss commonalities and differences. The resultant paper has now been published in Nature Metabolism rdcu.be/dZryb

rdcu.be

On the pathogenesis of obesity: causal models and missing pieces of the puzzle

Nature Metabolism - This authoritative Perspective lays a foundation for the field of obesity research by comparing commonalities and differences between competing models of obesity pathogenesis...

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Joe Matthews @josephmatthews.bsky.social · 21/11/2024

Irony intensifies: a story in three parts.

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Nick Tiller, Ph.D. @nbtiller.bsky.social · 19/11/2024

Left, a non-randomized study showing that saunas significantly decrease arterial stiffness. Right, a randomized, crossover study, showing no benefits on arterial stiffness/blood flow. Note the colossal difference in media attention. In the media, sensational studies > robust ones. #science #media

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Joe Matthews @josephmatthews.bsky.social · 14/11/2024

Sunset over the Arkansas river in Little Rock - view from the Big Dam Bridge 🌅

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Joe Matthews @josephmatthews.bsky.social · 14/11/2024

Blue Sky experience so far: • No gambling ads • No Temu ads • People interacting • Interesting science posts • I actually see the posts of people I follow We are so back!

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Darren Dahly @statsepi.bsky.social · 12/11/2024

In clinical research, you will often receive feedback on study design, stats, and/or data analysis from an editor or reviewer that is simply wrong. Here is a list of common "statistical myths" and references you can use to push back. discourse.datamethods.org/t/reference-...

discourse.datamethods.org

Reference Collection to push back against "Common Statistical Myths"

Note: This topic is a wiki, meaning that this main body of the topic can be edited by others. Use the Reply button only to post questions or comments about material contained in the body, or to sugge...

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Joe Matthews @josephmatthews.bsky.social · 13/11/2024

I enjoyed this a lot - Dr Eric Ravussin on the early metabolic chamber work and obesity research at Pennington Biomedical Research Centre 👇🏽 open.spotify.com/episode/63YG...

open.spotify.com

#324 ‒ Metabolism, energy balance, and aging: How diet, calorie restriction, and macronutrients influence longevity and metabolic health | Eric Ravussin, Ph.D.

The Peter Attia Drive · Episode

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Joe Matthews @josephmatthews.bsky.social · 13/11/2024

Original 1920s gymnasium in Hot Springs, Arkansas👇🏽 “This complete exercise centre has all the necessary equipment for a good work out.”

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