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Jorge FdCD

@jorgefdcd.bsky.social
819 followers 1.5K following 44 posts

CNRS researcher working at the Institut de Physique Théorique (IPhT) in Paris-Saclay. Interested in statistical physics, machine learning, and biological data modeling. Website: sites.google.com/view/jorgefdcd

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Jorge FdCD @jorgefdcd.bsky.social · 01/07/2026
@cnrs.fr published a popular summary of our recent work: Using recordings of whole-brain activity in zebrafish larvae, a French team has shown that it is possible to translate spontaneous neural activity between individuals without matching neurons one-to-one.
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Jorge FdCD @jorgefdcd.bsky.social · 16/06/2026
New preprint: Spherical Boltzmann machines: a solvable theory of learning and generation in energy-based models with Thomas Tulinski, Simona Cocco, Rémi Monasson 🧵
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Jorge FdCD @jorgefdcd.bsky.social · 16/06/2026
New preprint: Replica Theory of Spherical Boltzmann Machine Ensembles, with Thomas Tulinski, Simona Cocco, and Rémi Monasson Training usually means finding one model whose parameters minimize a loss. But sampling multiple models — ensemble learning — can sometimes do better.
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Jorge FdCD @jorgefdcd.bsky.social · 26/05/2026
Our work has been selected as a Spotlight Talk in the GenBio Workshop at ICML @icmlconf.bsky.social
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Jorge FdCD @jorgefdcd.bsky.social · 23/05/2026
How can we steer protein language models toward specific traits, without losing sequence diversity? In our new preprint, we introduce Iterative Lookback Monte Carlo (ILMC)—a training-free sampling strategy that balances generation quality, steering constraints, and diversity.
Iterative Lookback Monte Carlo (ILMC)
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Jorge FdCD @jorgefdcd.bsky.social · 14/05/2026
Just published in PNAS: www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Jorge FdCD @jorgefdcd.bsky.social · 12/01/2026
New preprint: Design and experimental characterization of specificity-switching mutational paths of WW domains.
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Jorge FdCD @jorgefdcd.bsky.social · 12/01/2026
New preprint: Cross-individual translation of spontaneous zebrafish brain activity through a shared latent representation
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Jorge FdCD @jorgefdcd.bsky.social · 21/12/2025
Just published in @natcomms.nature.com : Designing molecular RNA switches with Restricted Boltzmann machines. Full paper: www.nature.com/articles/s41...
nature.com
Designing molecular RNA switches with Restricted Boltzmann machines - Nature Communications
Riboswitches are allosteric RNA molecules that change conformation upon ligand binding to regulate downstream genes. Here, the authors use Restricted Boltzmann machines trained on natural sequences to...
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Jorge FdCD @jorgefdcd.bsky.social · 02/11/2025
Master internship position available, with possibility of PhD after. More details here: sites.google.com/view/jorgefd...
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Jorge FdCD @jorgefdcd.bsky.social · 30/06/2025
We invite early-career researchers to apply for the STARφ programme of Université Paris-Saclay, funded by the European Union under the Marie Skłodowska-Curie COFUND action. Our team at the IPhT at CEA-Saclay is among the participating laboratories.
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Jorge FdCD @jorgefdcd.bsky.social · 23/06/2025
An 14 months months postdoctoral positions is available in my team, to work on computational models of artificial evolution for aptamer design.
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Reposted by Jorge FdCD
Jorge FdCD @jorgefdcd.bsky.social · 23/01/2025
The summer school “Molecular Evolution and Design: from Computational Models to Biological and Medical Applications”, which we are organizing in Cargèse on Corsica island, will take place from August 19-29 2025 - the place is fantastic in summer ! 🧵
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Jorge FdCD @jorgefdcd.bsky.social · 08/05/2025
We are looking for a candidate for a PhD position shared between Gen&Chem group (BGE/IRIG) at CEA-Grenoble and IPhT at CEA-Saclay, combining expertise in statistical physics, computational biology and computer science. 🧵
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Jorge FdCD @jorgefdcd.bsky.social · 23/01/2025
The summer school “Molecular Evolution and Design: from Computational Models to Biological and Medical Applications”, which we are organizing in Cargèse on Corsica island, will take place from August 19-29 2025 - the place is fantastic in summer ! 🧵
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Jorge FdCD @jorgefdcd.bsky.social · 11/01/2025
I have an 18 months postdoc position available in Paris-Saclay, starting in March 2025, to work at the interface of machine learning, computational biology and statistical physics.
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Reposted by Jorge FdCD
Willie Neiswanger @willieneis.bsky.social · 20/11/2024
The first list filled up, so here's a second list of AI for Science researchers on bluesky. Let me know if I missed you / if you'd like to join! bsky.app/starter-pack...
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Reposted by Jorge FdCD
Jacob S. Zelko @thecedarprince.bsky.social · 08/11/2024
Hey folks! I got a bit swamped with all the new #julialang BlueSky people and made my own mega Julia #programmer starter pack! go.bsky.app/Hv4RKzM What other starter packs would you want to see? I'm in health research, mathematics, and open source/science. 🧪🛟🩺 📊
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