iiinova — where your digital self keeps evolving

Jongmin Kim @jongminkmg.bsky.social · 20/09/2026

Opportunity to work with a great mentor and do exciting science!

Reposted by Jongmin Kim

Weill Institute for Cell & Molecular Biology @weillinstitute.bsky.social · 12/09/2026

📣 We’re hiring! The Weill Institute for Cell and Molecular Biology and the Department of Biomedical & Translational Sciences are seeking a tenure-track Assistant Professor in Molecular Therapeutics. 🔬 Review begins November 15, 2026

apps.hr.cornell.edu

Academic Career Opportunities

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Jongmin Kim @jongminkmg.bsky.social · 01/09/2026

Cornell is an excellent place to study reproductive biology.

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Reposted by Jongmin Kim

Evgeny Kvon @evgenykvon.bsky.social · 24/08/2026

The newly established Department of Systems Biology (systems.bio.uci.edu) @UCIrvine is hiring a tenure-track Assistant Professor in Systems Biology. Great science, incredible faculty support, and beautiful, sunny SoCal weather! ☀️🌴 Details: recruit.ap.uci.edu/JPF10377. Please share.

recruit.ap.uci.edu

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Jongmin Kim @jongminkmg.bsky.social · 22/08/2026

"BRD4 protein does not need histone acetylation or even the H4 tail to bind with high affinity to nucleosomes" I think the same is true for cPRC1 CBX-nucleosome binding. Chromodomain-H3K27me3 interaction matters, but clusters of basic amino acids are also required. www.cell.com/molecular-ce...

cell.com

BRD4 binds the nucleosome via both histone and DNA interactions

Zhu et al. characterize how the transcriptional regulator BRD4 interacts with acetylated nucleosomes. Their cryo-EM structure shows that the first bromodomain of BRD4 binds both the acetylated histone...

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Jongmin Kim @jongminkmg.bsky.social · 18/06/2026

I always thought tTAF in the nucleolus in fly spermatocytes was odd. It turns out that, during spermatogenesis, the Pol I-enriched nucleolus becomes a Pol II- and TFIID-enriched nucleolus-like body. This structure seems important for transcription of huge, normally heterochromatic Y-linked genes.

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Jongmin Kim @jongminkmg.bsky.social · 27/04/2026

Canonical PRC1 excludes SWI/SNF, and its subunit composition (e.g., which CBX) can change the competition outcome. Fig 1D (magenta: cPRC1, cyan: SWI/SNF)

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Jongmin Kim @jongminkmg.bsky.social · 19/04/2026

Great postbac opportunity - exciting biology and an excellent mentor!

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Jongmin Kim @jongminkmg.bsky.social · 02/04/2026

Germline - unique chromatin environment, different versions of core components, and many discoveries ahead.

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Jongmin Kim @jongminkmg.bsky.social · 08/12/2025

- Independent localization of H2AK119Ub and H3K27me3 in worm embryos. - Removing Ub did not influence K27me3 levels, and vice versa. - It is interesting that different cells/organisms utilize conserved chromatin-modifying machineries differently. www.science.org/doi/10.1126/...

science.org

Widespread association of Polycomb complex–deposited histone H2A monoubiquitylation with enhancers and neuronal gene regulation

Genome-wide profiling reveals histone H2A monoubiquitylation as a signature of both Polycomb-repressed and enhancer chromatin.

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Jongmin Kim @jongminkmg.bsky.social · 23/10/2025

We did journal club today on this preprint - interesting parallels that CHD4 and its partners block aberrant TF binding in mESCs (this preprint), human cells (PMID:38281186), and fly testis (PMID:28522526). Fascinated by how CHD4 controls cryptic regulatory elements without a strong presence there.

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Jongmin Kim @jongminkmg.bsky.social · 18/09/2025

Exciting work on orphan genes in fertilization and evolution!

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Jongmin Kim @jongminkmg.bsky.social · 31/08/2025

Avidity. In plants, PRC2 accessory VEL proteins polymerize much like PRC1 subunits in animals, reinforcing silencing. Multimerization - overcoming weak affinity through 'avidity' - seems to be an important conserved principle in chromatin regulation. pubmed.ncbi.nlm.nih.gov/40858112/

pubmed.ncbi.nlm.nih.gov

VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing - PubMed

Multivalent protein-chromatin interactions facilitated by higher-order protein assemblies are emerging as a crucial theme in eukaryotic gene regulation. However, understanding the underlying mechanism...

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Jongmin Kim @jongminkmg.bsky.social · 25/08/2025

Donated. FlyBase is a truly essential resource!

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Jongmin Kim @jongminkmg.bsky.social · 18/06/2025

Reducing H1 levels (by CRAMP1 KD) derepresses PRC2 target genes without reducing H3K27me3. It was interesting: 1) once again, H3K27me3 mark alone seems not sufficient for gene repression, 2) how is H1 deposited at Polycomb target sites? Congrats, Iva!

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Jongmin Kim @jongminkmg.bsky.social · 13/06/2025

True: my ESI MIRA, submitted last February, was withdrawn three weeks before the study section because of a support letter. No sub-award, no expected co-authorship, just a letter. So be careful - their definition of 'collaboration' is very broad.

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Jongmin Kim @jongminkmg.bsky.social · 06/06/2025

I find unstructured regions in proteins enigmatic and very interesting.

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Jongmin Kim @jongminkmg.bsky.social · 13/03/2025

" The common genetic marker Stubble influences Fab2L transgene expression" - balancer and marker mutations are not always inert.

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Reposted by Jongmin Kim

Patrick Murphy @pjmurphy249.bsky.social · 28/01/2025

Today’s the day! I’m happy to announce that the Murphy Lab will be moving to Cornell this July! The lab will be in Biotech and I’ll be joining the Department of Molecular Biology and Genetics. There will be lots of recruiting soon, including students and postdocs. Please RT. 🙏 TY.

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Jongmin Kim @jongminkmg.bsky.social · 22/01/2025

Great opportunity for postbacs to do exciting research and gain experience before graduate school!

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Jongmin Kim @jongminkmg.bsky.social · 21/01/2025

The sun has been rather scarce in Ithaca lately. Nice to see some sunrise this morning.

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Reposted by Jongmin Kim

Seungsoo Kim @seungsookim.bsky.social · 20/01/2025

Hello Bluesky friends! I am a #newPI starting at UC Irvine in April, interested in gene regulation and functional genomics in stem cell models of development (esp neural crest). We are hiring at all levels – please reach out/spread the word! sskimlab.org

sskimlab.org

Kim Lab at UC Irvine

Visit the post for more.

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