Cytotoxic chemotherapy remains the standard-of-care treatment for patients with pancreatic ductal adenocarcinoma (PDAC). However, chemotherapy only has modest effects at improving patient survival due...

Chronic inflammation in autoimmunity is driven by T cell hyperactivation. This unregulated response to self is fuelled by heightened metabolic programmes, which offers a promising new direction to unc...

The gut microbiome plays a crucial role in cancer development and progression, by influencing the host immune system and metabolism.

ALT: a bald man in a blue suit is making a funny face and pointing at something .