iiinova — where your digital self keeps evolving

Johan Slotman @johanslotman.bsky.social · 05/10/2026

This is very great news, last week we had a very succesfull optogenetics workshop organized by the Optical Imaging Centre and specifically @jeffreyharen.bsky.social Nice to see this great technology and scientists involved rewarded.

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Johan Slotman @johanslotman.bsky.social · 29/07/2026

Made pigs fly 😂 work can be fun, learning rust and wgpu. Might be very useful for creating simulations. Good to keep flexible in programming, now back to writing grant proposals.

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Johan Slotman @johanslotman.bsky.social · 03/07/2026

Proud to share this next step in the ongoing story of meiotic break foci. Aditya Mhaskar set out to reconstitute DMC1 (a meiotic specific recombinase) in mitotic cells. DNA breaks are recognized and repaired by both RAD51/DMC1. www.frontiersin.org/journals/cel...

frontiersin.org

Frontiers | Modelling DMC1 mediated homologous recombination repair in mouse embryonic stem cells

IntroductionProgrammed DNA double-strand break (DSB) formation and repair are central to meiotic homologous chromosome pairing in mammals. In meiotic cells, ...

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Reposted by Johan Slotman

Lluis Montoliu @lluismontoliu.bsky.social · 28/06/2026

Frank Grosveld, born in 1948, passed away last Friday. He was a colossal scientist in the transcriptional control of gene expression during development and helped us understand the complex regulation of beta-globin genes. His work will remain as a reference. May he rest in peace.

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Johan Slotman @johanslotman.bsky.social · 11/05/2026

One of the reasons science was exciting when I was young. Hearing stuff about DNA and the human genome project made me choose to do a laboratory education. RIP mr. Venter.

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Johan Slotman @johanslotman.bsky.social · 01/05/2026

Another great Erasmus MC collaboration by the department of viroscience, psychiatry and the Optical Imaging Centre. This study shows the effects of influenza A virus infection to (iPSC derived) neurons. Great work by the excellent and phd student Feline Benavides link.springer.com/article/10.1...

link.springer.com

Influenza A virus infection impairs neuronal activity in human iPSC-derived NGN2 neural co-cultures - Acta Neuropathologica Communications

Acta Neuropathologica Communications - Influenza A virus (IAV) infection is associated with a wide variety of neurological complications, of which mild complications like impaired cognitive...

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Reposted by Johan Slotman

Tom Gauld @tomgauld.bsky.social · 21/04/2026

My latest cartoon for @newscientist.com

Three cool scientists introduce their work "Our new theory has been submitted to a peer-reviewed journal, but we feel its depths and intricacies are best appreciated on the limited-edition vinyl release."

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Johan Slotman @johanslotman.bsky.social · 20/04/2026

Work by Daan te Rietmole, Gerard Jansen, @bieringslab.bsky.social @shordijk.bsky.social, Maurice Swinkels, Petra Bürgisser, Bart Geverts, Joyce Besteboer, Ihor Smal, Thomas Klei, Adriaan Houtsmuller and Frank Leebeek

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Johan Slotman @johanslotman.bsky.social · 15/04/2026

Hey Science bluesky. Is there a name for the period between the acceptation email of a paper and when it actually pops up on the website of the journal? 😉

media.tenor.com

an elderly woman is crying and says it feels like it 's been 84 years

ALT: an elderly woman is crying and says it feels like it 's been 84 years

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Reposted by Johan Slotman

Selçuk Yavuz @selcuk61yavuz.bsky.social · 16/12/2025

Wondering how a fully automated confocal microscopy setup could help biologists with rapid acquisition of quantitative imaging data? Check now our new article published in #FEBS Open Bio: febs.onlinelibrary.wiley.com/doi/10.1002/...

febs.onlinelibrary.wiley.com

FEBS Press

RoboMic is an automated confocal microscopy pipeline for high-throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI-driv...

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Johan Slotman @johanslotman.bsky.social · 16/12/2025

Getting SMART about FRAP enabled us to make many FRAP curves in one imaging session. Now we are doing things like 18 conditions n = 30 in a single overnight session. Study protein dynamics in high throughput. Curious on how? see our publication: febs.onlinelibrary.wiley.com/doi/full/10....

febs.onlinelibrary.wiley.com

FEBS Press

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Johan Slotman @johanslotman.bsky.social · 14/11/2025

We're having a great Functional Imaging and Super-Resolution Microscopy course this year again. With engaged students learning about FRAP, FRET, STED, FLIM and many more (not necessarily 4 letter) fluorescent microscopy techniques. But also a really nice talk by Ben Giepmans about ColorEM.

Picture of Ben Giepmans Giving a talk at the natuurhistorisch museum, You see a slid about reuse of EM data and a room with names of biologists on the wall and several pieces from the collection of the musuem like a bust with a deer and prepared antlers

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Johan Slotman @johanslotman.bsky.social · 18/08/2025

Fun to see a lightsheet image, made at the Erasmus OIC by Lieke Stockman be awarded with the second prize, in the bruker lightsheet image competition. www.bruker.com/en/products-...

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Johan Slotman @johanslotman.bsky.social · 28/07/2025

It's the time of the year (just before holiday) where I can do some random stuff to keep the python muscles warm. Here is a simulation of particles with different movement types in different containers. The bubble like structure was hard to code, but it mostly works. youtu.be/2YuseN3GGKc

youtu.be

Particle movement types in different containers

YouTube video by Johan Slotman

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Johan Slotman @johanslotman.bsky.social · 06/06/2025

Sometimes you have to deal with some inevitable truths, like proton beam angle that is fixed. So we flipped a microscope in order to see the effect of proton irradiation on live cells to carefully quantify DNA damage and determine dosage. Read more here: www.sciencedirect.com/science/arti...

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Johan Slotman @johanslotman.bsky.social · 03/03/2025

So lets try bluesky as well for science. I'm an assistant professor focusing on advanced fluorescent imaging and image analysis and part of the Erasmus MC Optical Imaging Centre core facility.

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