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jofoth.bsky.social

@jofoth.bsky.social
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Michael Brockhurst @brockhurstlab.bsky.social · 06/10/2025
5-years in the making this paper has been a real journey! Also, a fun collaboration with @frimanscience.bsky.social @jofoth.bsky.social Edze Westra, Simon Lovell, Aras Kadioglu #mevosky #phagesky
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Vivek Mutalik @vivekmutalik.bsky.social · 27/07/2025
#microsky
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Siân Owen @sianowen.bsky.social · 28/05/2025
Phage DisCo! Our targeted phage discovery method in press today: journals.asm.org/doi/10.1128/... Perfectly timed with our four summer undergrad's first successful phage hunt... disco lights in the lab to mark the occasion 🕺
Disco lights
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Emmanuele Severi @emmseveri.bsky.social · 18/06/2025
#phagesky www.cell.com/trends/micro...
cell.com
Phage tRNAs: decoding the enigma
The presence of tRNAs in bacteriophage genomes has intrigued scientists since their discovery in the early 1960s, as phages were believed to rely on the host tRNAs for their translation. Over the year...
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Meaghan Castledine @mcastd.bsky.social · 23/06/2025
New phage therapy publication!🦠 #phagesky We analysed an MRSA phage therapy case study, assessing how predictions made in vitro differed when using one (standard practice) or multiple bacteria isolates from the patient. Collaborative work: Exeter and Queen Astrid hospital doi.org/10.1093/jamb...
doi.org
Predicting clinical phage therapy outcomes in vitro: results using mixed versus single isolates from an MRSA case study
AbstractAims. In phage therapy case studies, 1–3 bacteria isolates are typically tested against phages (phagogram). However, as bacteria populations differ
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Jack A Gilbert @gilbertjacka.bsky.social · 23/06/2025
New Consensus Statement in Nature Microbiology! Working with low-biomass microbiome samples? From deep subsurface rocks to human lungs, contamination is a major challenge. We offer field-to-data analysis guidelines to help keep your results clean. 📖 doi.org/10.1038/s415...
doi.org
Guidelines for preventing and reporting contamination in low-biomass microbiome studies - Nature Microbiology
In this Consensus Statement, the authors outline strategies for processing, analysing and interpreting low-biomass microbiome samples, and provide recommendations to minimize contaminants.
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Siân Owen @sianowen.bsky.social · 06/07/2025
Whoa, F-pilus dependent phage MS2 whips off it's capsid before entry into the cell?? www.sciencedirect.com/science/arti... "Extracellular uncoating of bacteriophage MS2" #phagesky
sciencedirect.com
Extracellular uncoating of bacteriophage MS2
In the early stages of infection of its host, Escherichia coli, bacteriophage MS2 sheds its icosahedral protein capsid, after which the single-strande…
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Trevor Lithgow @trevor-lithgow.bsky.social · 17/07/2025
We have been working on ways to find #phage with long shelf-life and this one is a winner. 12 months freeze-thawing as much as you like, no loss of viability #phageSky #microSky rdcu.be/ewnzT
rdcu.be
Highly stable bacteriophages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria
npj Viruses - Bacteriophages (phages) are viruses that kill bacteria, with potential as antibacterial agents in industrial settings, agriculture, and human health. Here, we identified two phages,...
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Emmanuele Severi @emmseveri.bsky.social · 23/07/2025
#phagesky www.biorxiv.org/content/10.1...
biorxiv.org
Temperate phages enhance host fitness via RNA-guided flagellar remodeling
Bacterial flagella drive motility and chemotaxis while also playing critical roles in host-pathogen interactions, as their oligomeric subunit, flagellin, is specifically recognized by the mammalian im...
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Vivek Mutalik @vivekmutalik.bsky.social · 23/07/2025
#phage #phagesky
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Vivek Mutalik @vivekmutalik.bsky.social · 27/07/2025
#phage #phagesky www.biorxiv.org/content/10.1...
biorxiv.org
PRISM: A platform for illuminating viral dark matter
The exploration of bacteriophage diversity remains constrained by reliance on conventional plaque assays, which bias discovery toward phages that form visible plaques and propagate efficiently. The di...
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Ruairi Robertson @ruairirobertson.bsky.social · 12/09/2024
💊 Antibiotics damage the gut barrier via impaired mucus production independently of the microbiota. A consideration for those using antibiotic induced depletion of the microbiome in mice www.science.org/doi/10.1126/sciadv.…
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shampadaspkpd.bsky.social @shampadaspkpd.bsky.social · 03/12/2024
We're advertising a fully funded PhD to explore the PK-PD of Phage therapy being developed for the treatment of Cystic Fibrosis lung infections. The post is in the Department of Pharmacology and Therapuetics at the University of Liverpool. @livuni-ismib.bsky.social @jofoth.bsky.social
findaphd.com
Exploring the PK-PD of Phage therapy being developed for the treatment of Cystic Fibrosis lung infections at University of Liverpool on FindAPhD.com
PhD Project - Exploring the PK-PD of Phage therapy being developed for the treatment of Cystic Fibrosis lung infections at University of Liverpool, listed on FindAPhD.com
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Ellie Rand @ellie-rand.bsky.social · 23/11/2024
Phage DisCo can be further multiplexed with three bacterial strains in co-culture, and, when tested with characterized phages, the fluorescent signal shined! Maybe you can see where the disco ball comparison comes in here. 🪩 4/
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 25/11/2024
a triangle 🔺 it’s a basic shape, but no bacteria is a triangle a clothes hanger, a slice of pizza, a dorito—all triangles just not bacteria
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Willem van Schaik @wvschaik.bsky.social · 30/10/2024
Please sign up, it will be fun! Open for all with an interest in AMR and genomics (in the UK and elsewhere). www.targetamr.org.uk (and please give @target-amr.bsky.social a follow!)
targetamr.org.uk
TargetAMR – Reducing AMR through Genomics
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