Join CDC each September for Fungal Disease Awareness Week (FDAW). <em>Think fungus</em> to save lives.

This course addresses the need for more research in the area of fungal diseases as our understanding of the basic pathophysiology of fungal disease lags far behind our understanding of many common bac...

SUMMARYFungal pathogens cause widespread disease in humans, plants, and animals. Surviving in diverse environments requires fungi to resist attack by a wide range of reactive chemicals, including reac...

Abstract. The ability of Candida albicans to resist stressful conditions in the host and grow invasively into tissues contributes to the virulence of this

The ability of Candida albicans to grow invasively in the host and resist stress is critical for it to be an effective human pathogen. Identifying the genes that promote these processes is important f...

Millions of hibernating bats across North America have died from white-nose syndrome (WNS), an emerging disease caused by a psychrophilic (cold-loving) fungus, Pseudogymnoascus destructans, that invad...

Quiescence is a common cellular state, required for stem cell maintenance and microorganismal survival under stress conditions or starvation. However,…

Cryo-electron microscopy, in vitro reconstitution and molecular dynamics simulations provide insight into the architecture of a plasma membrane microdomain in yeast, the organization and dynamics of t...

Hypochlorous acid (HOCl), commonly known as bleach, is generated during the respiratory burst by phagocytes and is a key weapon used to attack Candida albicans and other microbial pathogens. However, the effects of hypochlorous acid on C. albicans have ...

The human fungal pathogen Candida albicans can cause lethal systemic infections due to its ability to resist stress from the host and to undergo invasive hyphal growth. Previous studies showed that pl...