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JKNowak Lab

@jknowaklab.bsky.social
21 followers 9 following 5 posts

Institute of Biochemistry and Biophysics PAS, Warsaw, POLAND We study the mechanisms that are responsible for the synthesis of developmentally regulated non-coding RNAs and their role in programmed genome rearrangements.

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JKNowak Lab @jknowaklab.bsky.social · 09/05/2025
We are looking for a PhD student to study non-coding RNA in Paramecium! ibb.edu.pl/app/uploads/...
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Reposted by JKNowak Lab
iimcb.bsky.social @iimcb.bsky.social · 16/04/2025
🧬mRNA vaccines played a key role in controlling the spread of the pandemic. However, mRNA itself is an exceptionally unstable molecule. This limits its effectiveness - for example, by shortening the duration of action. In our research, we examined these limitations 👨‍🔬👩‍🔬
nature.com
Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines - Nature
Upon intramuscular administration, COVID-19 mRNA vaccines are primarily taken up by macrophages, in which the cellular machinery extends their poly(A) tails, thereby increasing mRNA stability and tran...
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JKNowak Lab @jknowaklab.bsky.social · 24/01/2025
I am looking for a post-doctoral researcher to join my team. #ncRNA #RNApol #epigenetics #ciliates #Paramecium ibb.edu.pl/app/uploads/...
ibb.edu.pl
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JKNowak Lab @jknowaklab.bsky.social · 13/01/2025
It is great to have a cover at #NAR for our Breakthrough Article doi.org/10.1093/nar/... Research done at #IBB_PAS thanks to the funds from @ncngovpl.bsky.social Collaboration with @sandraduharcourt.bsky.social
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JKNowak Lab @jknowaklab.bsky.social · 29/11/2024
doi.org/10.1093/nar/... In order to introduce myself here, I would like to share our recent paper published as Breakthrough Article at #NAR. Great collaboration with Duharcourt @sandraduharcourt.bsky.social team and the financial support from #NCN @ncngovpl.bsky.social. #smallRNAs #Paramecium
doi.org
The PIWI-interacting protein Gtsf1 controls the selective degradation of small RNAs in Paramecium
Abstract. Ciliates undergo developmentally programmed genome elimination, in which small RNAs direct the removal of transposable elements (TEs) during the
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