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jjparienti.bsky.social

@jjparienti.bsky.social
764 followers 227 following 163 posts

🇫🇷 MD, PhD Stat | Prof. Public Health | 🆔 Consultant | AEditor @CID @JID @OFID | Chess♟️| Poker♦️| Lampshade 💡 Best Handmade lampshades: www.etsy.com/fr/shop/Etincellecreat…

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jjparienti.bsky.social @jjparienti.bsky.social · 23/09/2026
New form of #Immortal #Bias affecting US people dying with #measle? In an epidemic, robust death estimates are needed - not necessarily the attributable mortality for each case 😵‍💫💁🏻‍♂️😉💉 www.theguardian.com/us-news/2026...
theguardian.com
Why the CDC is excluding measles deaths in Pennsylvania even as outbreak appears to be ‘accelerating’
Centers for Disease Control and Prevention refuses to count four measles deaths in the state though doctors are ‘seeing new forms’ of disease
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jjparienti.bsky.social @jjparienti.bsky.social · 18/07/2026
The goal was to make this advanced causal inference approach more accessible and demonstrate its real-world value in antibiotic stewardship research. The comment also acknowledges that Level 2 for evidence cannot by Magic become Level 1, even if it’s the « Target ».
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jjparienti.bsky.social @jjparienti.bsky.social · 30/04/2026
Closing Open Evidence to European HCP sucks
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jjparienti.bsky.social @jjparienti.bsky.social · 30/03/2026
#HIV #ART #Safety Happy to share a commentary of 2 target trial emulations #TTE linking metabolic complications to #INSTI switch published in #TLHIV www.thelancet.com/journals/lan...
thelancet.com
Metabolic syndrome and cardiovascular risk on INSTIs
Treatment regimens containing integrase strand-transfer inhibitors (INSTIs) are taken lifelong by most people with HIV. The potency, tolerability, and high resistance barrier of INSTIs make them the t...
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jjparienti.bsky.social @jjparienti.bsky.social · 03/12/2025
Does subclavian CVC still carry higher pneumothorax risk in the ultrasound era? 🫁 New emulated reanalysis of the 3SITES RCT shows: ❌ Subclavian excess PNO risk DISAPPEARS with ultrasound ✅ LOWER CRBSI w subclavian vs jugular/femoral link.springer.com/article/10.1...
link.springer.com
Site-specific complications of central venous catheterization under systematic ultrasound guidance: a target trial emulation revisiting the 3SITES study - Critical Care
Background Central venous catheterization is the most common invasive procedure in intensive care units but remains burdened by infectious, thrombotic, and mechanical complications. Although real-time...
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jjparienti.bsky.social @jjparienti.bsky.social · 16/11/2025
Proud to hit 100 peer-reviews for @TheLancetHIV! 🎉 As a stats reviewer, here are 3 red flags 🛑😒that yields to reject⛔️: 1️⃣ Cc driven by hypothesis, not data 🙄 2️⃣ Primary outcome swap for p-value 🕵🏻‍♂️ 3️⃣ Stats copy-pasted 🤡 by ppl who don’t understands it #HIV #peerRW
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jjparienti.bsky.social @jjparienti.bsky.social · 25/10/2025
My birth date (DD/MM/YY) is not just a #palindrome It combines the #worst and the #best hand in #poker 27 - AA - 72 ! 😅😉
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jjparienti.bsky.social @jjparienti.bsky.social · 20/10/2025
Cluster of 3 lampshades Colors are not random Do you like the intra-class correlation? #Handmade in 🇫🇷
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jjparienti.bsky.social @jjparienti.bsky.social · 20/10/2025
In the context of vaccine hesitancy😱, this outstanding research🤩highlights decades of dedicated efforts to develop safe and effective vaccines💉. 🛟🛟🛟 Smallpox eradication to modern innovations, 👀 history and rigorous processes behind these life-saving tools. FREE! academic.oup.com/cid/issue/81...
academic.oup.com
Volume 81 Issue Supplement_2 | Clinical Infectious Diseases | Oxford Academic
An official journal of the Infectious Diseases Society of America. Publishes on clinical descriptions of infections, public health, microbiology, and immunology; infection prevention; treatment evalua...
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jjparienti.bsky.social @jjparienti.bsky.social · 17/10/2025
Masterclass présentation by Prof. Anne-Genevieve Marcelin on new ART @eacsociety.bsky.social #EACS2025Paris NO SEAT AVAILABLE! #IDSky #HIVSky
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jjparienti.bsky.social @jjparienti.bsky.social · 02/10/2025
Let’s go dismantle the methodological puzzle of the link btw InSTI and cardiometabolic risk among #PWH at #SynergieResistance #Aix_en_provence The thème is Gardian of the Galaxy! #RESPOND #SwissCohort #HIV_Causal
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NEJM.org @nejm.org · 17/09/2025
RSV remains a severe infection in infants and children. In this report, data on the activity of clesrovimab, a long-lasting RSV monoclonal antibody, are described as compared with palivizumab. Full interim results for the SMART phase 3 trial: nej.md/4poVkDE #MedSky #IDSky #PedSky
Table 2. Incidence of RSV-Associated Secondary End Points in RSV Season 1.
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jjparienti.bsky.social @jjparienti.bsky.social · 15/09/2025
Sometimes correlation does not mean causation Sometimes outlier does not improve precision Sometimes it does.
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jjparienti.bsky.social @jjparienti.bsky.social · 30/08/2025
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Greg Folkers @gregfolkers.bsky.social · 14/08/2025
CID: Background HIV Incidence in PURPOSE 1 and 2 PrEP trials Jean-Jacques Parienti HIV incidence among low-adherence oral PrEP users in PURPOSE 1 and 2 closely matched or slightly exceeded background HIV incidence bit.ly/4ltz5JO
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jjparienti.bsky.social @jjparienti.bsky.social · 14/08/2025
What if comparing : 🔵 background #HIV incidence (MODEL) to 🔴 HIV incidence (REAL) among ppl w low-level adherence to oral #PrEP (<2💊/wk by DBS- unprotected) in PURPOSE trials? 👇🏾👇🏽👇🏻👇 academic.oup.com/cid/advance-...
academic.oup.com
Background HIV Incidence in PURPOSE 1 and 2 PrEP trials
Abstract. HIV incidence among low-adherence oral PrEP users in PURPOSE 1 and 2 closely matched or slightly exceeded background HIV incidence (bHIV), suppor
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jjparienti.bsky.social @jjparienti.bsky.social · 23/07/2025
While ivermectine does not kill SARS-CoV-2, it reduced malaria by killing mosqitoes www.nejm.org/doi/full/10....
nejm.org
Ivermectin to Control Malaria — A Cluster-Randomized Trial | NEJM
Malaria control and elimination is threatened by the spread of insecticide resistance and behavioral adaptation of vectors. Whether mass administration of ivermectin, a broad-spectrum antiparasitic...
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jjparienti.bsky.social @jjparienti.bsky.social · 24/06/2025
If you prevent effective prevention against diseases to happen, can we say you cause the disease?
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jjparienti.bsky.social @jjparienti.bsky.social · 23/06/2025
Viral dynamics 🦠 and clinical outcome 🏥☠️ from resp. virus: 💊 that ⏬ VL tend to ⏬ poor outcome Good to see a confirmation by #NIH team from an IPDMA, with implications for surrogacy in phase II clinical trials 😉🤩 In press @jidjournal.bsky.social academic.oup.com/jid/advance-...
academic.oup.com
The Choice of Viral Load End Point in Early Phase Trials of COVID-19 Treatments Aiming to Reduce 28-Day Hospitalization and/or Death
This meta-analysis uses individual participant data to evaluate various SARS-CoV-2 viral load outcomes as surrogates for 28-day hospitalization/death. Chan
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jjparienti.bsky.social @jjparienti.bsky.social · 19/05/2025
Measles outbreak in Texas: low vaccination (93%), anti-vax sentiment, and rising exemptions. No Texas Hold'em here, just a bad bluff against measles! #GetVaccinated
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Karine Lacombe @lacombekarine.bsky.social · 18/04/2025
Après @etienneklein.bsky.social le défi de la plénière pour @nicolasberrod.bsky.social « les fausses informations se propagent très vite sur les réseaux sociaux, et de façon beaucoup plus rapide qu'une vraie information.
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jjparienti.bsky.social @jjparienti.bsky.social · 31/03/2025
Like for DTG monotherapy
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jjparienti.bsky.social @jjparienti.bsky.social · 05/03/2025
MS submitted to scientific Journal #PeerReview Qualitative reviewers asking for a specific #Stat review has low Sensitivity but an excellent Positive Predictive Value to detect methodologically flawed papers
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Paul Sax @paulsaxmd.bsky.social · 18/02/2025
At Clinical Infectious Diseases @cidjournal.bsky.social, we are looking to fill 2 critical editorial positions. - Clinical microbiology - ID complications of transplantation and cancer treatments, in particular the latter. Full descriptions below and at link. Apply! academic.oup.com/idsa/pages/c...
text description of open positions
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The Lancet Infectious Diseases @thelancetinfdis.bsky.social · 11/02/2025
New Personal View: Targeting the SARS-CoV-2 reservoir in long COVID www.thelancet.com/journals/lan...
thelancet.com
Targeting the SARS-CoV-2 reservoir in long COVID
There are no approved treatments for post-COVID-19 condition (also known as long COVID), a debilitating disease state following SARS-CoV-2 infection that is estimated to affect tens of millions of peo...
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IDSA @idsainfo.bsky.social · 10/02/2025
Massive cuts to funding for the National Institutes of Health will eliminate the promise of lifesaving medical treatments for millions of Americans of all ages, says IDSA President Tina Tan, MD, FIDSA, FPIDS, FAAP. Our statement: buff.ly/4hNBHRd
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Paul Sax @paulsaxmd.bsky.social · 09/02/2025
We must remember is that childhood deaths and disability have a disproportionate effect on years of healthy life lost. It's why childhood immunizations against infectious threats are so important, and why they are one of the greatest scientific advances in history. srhd.org/news/srhd-re...
srhd.org
SRHD Reports Pertussis Death in Spokane County
The Spokane Regional Health District (SRHD) announces the first confirmed death from pertussis (whooping cough) in Washington since 2011.
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jjparienti.bsky.social @jjparienti.bsky.social · 07/02/2025
Ready to deliver a session about métabolic complication in #PWH #HIV #Paris
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jjparienti.bsky.social @jjparienti.bsky.social · 31/01/2025
Is INSTI/TAF exposure associted with incident hypertension? Réf: Hsue, Waters, Orkin et al. P283, HIV Glasgow 2024 #HIVSky
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Ian Weissman, DO @drianweissman.bsky.social · 26/01/2025
The CDC has been issuing advisories as bird flu spreads. The blackout will now prohibit external communications to the public..One person has altesdy died from the #birdflu. newsnationnow.com/health/feder...
newsnationnow.com
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jjparienti.bsky.social @jjparienti.bsky.social · 25/01/2025
Censorship of emerging ID information is not cost-effective
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Roger Paredes @rutgerwalls.bsky.social · 21/01/2025
We are looking for an Infectious Disease specialist who is truly passionate about understanding and curing Long Covid to join our ID department immediately. Full job description in Catalan, Spanish and English here: lnkd.in/d6jJ6yWt Please repost. Thanks!
lnkd.in
Hospital Universitari Germans Trias i Pujol on LinkedIn: #malaltiesinfeccioses #enfermedadesinfecciosas #infectiousdiseases
✅ A l’Hospital Universitari Germans Trias i Pujol estem buscant un/a Facultatiu/iva especialista en #malaltiesinfeccioses per incorporar-se al Servei de…
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jjparienti.bsky.social @jjparienti.bsky.social · 13/01/2025
Omaha beach golf & Port-en-Bessin @low-tide
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jjparienti.bsky.social @jjparienti.bsky.social · 13/01/2025
New CONSORT guideline on cluster-crossover RCT www.bmj.com/content/388/... @jomckenzie.bsky.social
bmj.com
Reporting of cluster randomised crossover trials: extension of the CONSORT 2010 statement with explanation and elaboration
This article presents the CONSORT (consolidated standards of reporting trials) extension for cluster randomised crossover trials. A cluster randomised crossover trial involves randomisation of groups ...
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jjparienti.bsky.social @jjparienti.bsky.social · 11/01/2025
French HIV prescribers switch ART for simplicity and better tolerance They think ART-related weight gain can be moderated by doravirine journals.lww.com/aidsonline/a... Let’s wait ACTG 5391 RCT! #HIVSky #IDSky
journals.lww.com
Factors influencing antiretroviral therapy switching in... : AIDS
ART, with a particular focus on doravirine-based regimens, in routine clinical practice in France. Design: This analysis of cross-sectional baseline data is part of the DoraVIH study, a French, mul...
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jjparienti.bsky.social @jjparienti.bsky.social · 07/01/2025
A high following/follower ratio is a major criteria, 5 points Playing golf scores 1 point No wrinkles scores 2 points Fancy background on the pic profile, 1 point What are the other criteria?
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jjparienti.bsky.social @jjparienti.bsky.social · 01/01/2025
Last participant included in first phase of DRIVE-OFF ROAD NCT06034938 investigating #DOR #TDF #3TC in ppl w #HIV and M184V/I #DRM 👏
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jjparienti.bsky.social @jjparienti.bsky.social · 30/12/2024
🟠 Long-term benefit* of MOL in SARS-CoV-2 infection among high risk #Vax ppl *should be interpreted w extreme caution since open label and differential F/up btw arms: more lost of F/up in control) = possible attrition bias #IDSky #MedSky #COVID www.thelancet.com/journals/lan...
thelancet.com
Health outcomes 3 months and 6 months after molnupiravir treatment for COVID-19 for people at higher risk in the community (PANORAMIC): a randomised controlled trial
In a vaccinated population, people treated with molnupiravir for acute COVID-19 felt better, experienced fewer and less severe COVID-19 associated symptoms, accessed health care less often, and took less time off work at 6 months. However, the absolute differences in this open-label design are small with high numbers needed to treat.
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jjparienti.bsky.social @jjparienti.bsky.social · 26/12/2024
Torchlight descent yesterday on the legendary Bellevarde slope in Val d'Isère, illuminated by fireworks!
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jjparienti.bsky.social @jjparienti.bsky.social · 25/12/2024
No cloud in The Sky Joyeux Noël !🎄🎁
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jjparienti.bsky.social @jjparienti.bsky.social · 24/12/2024
On my back from swimming pool in Val d’Isère 🎿⛷️ Nice ski house in the city center With it’s own red wine reserve ! MERRY CHRISTMAS !
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jjparienti.bsky.social @jjparienti.bsky.social · 19/12/2024
Prof. Didier Raoult once said: « The doctor can and must think as a doctor, and not as a methodologist ». Well, I’m afraid this does not hold for doctors conducting clinical research? www.nature.com/articles/d41...
nature.com
Controversial COVID study that promoted unproven treatment retracted after four-year saga
Paper on hydroxychloroquine led by French researcher Didier Raoult is second-most-cited study ever to be withdrawn.
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jjparienti.bsky.social @jjparienti.bsky.social · 18/12/2024
Fungi identification not just a mycologues lab issue 🔬🤭 🚨Can you name these? 😋
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jjparienti.bsky.social @jjparienti.bsky.social · 13/12/2024
🥰 In the context, it could be understood that the Science cover illustrates sexual partners. Do not think these ppl have flirted. 🙄 🤔 A man and woman holding LENACAPAVIR means it can protect gender diverse people #HIVSky 😊👏😉
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jjparienti.bsky.social @jjparienti.bsky.social · 12/12/2024
This picture shows why RWE analyses are not univocal or one-way for causal interpretation 🚨 Big Data not enough 🙄 🟢 Needs Data granularity 🔵 Needs Qualitative expertise 🟣 Needs Statistical expertise This means a team
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jjparienti.bsky.social @jjparienti.bsky.social · 09/12/2024
Incredibly how many AI generated asian females are Flying in this Blue Sky
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jjparienti.bsky.social @jjparienti.bsky.social · 07/12/2024
With 2 objective measures of ART adherence, mainly B/F/TAF 🔵 electronic sensor 🟢 intraerythrocytic drug concentrations 👏👏👏👏 🟣 Low level #HIV-RNA viremia 20-199 cp/mL was common despite high adherence 👉🏻 re-check LLV, most are blips rather than start of VF academic.oup.com/cid/article-...
academic.oup.com
Tenofovir-Diphosphate and Emtricitabine-Triphosphate Adherence Benchmarks in Dried Blood Spots for Persons With HIV Receiving Tenofovir Alafenamide and Emtricitabine–Based Antiretroviral Therapy (QUAN...
Tenofovir alafenamide/emtricitabine-based antiretroviral tablets, co-encapsulated with an ingestible sensor, directly measured adherence during a 16-week p
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jjparienti.bsky.social @jjparienti.bsky.social · 07/12/2024
🚨Want to boost your #interior #design ? Maison Thevenon 🇫🇷 best choice for elegance? Look at the creative tissue 👇🏾👇🏼👇🏾👇 New curtains, cushions or lampshade? I love it 🥰 www.thevenon1908.com/nos-tissus/
thevenon1908.com
Nos tissus - Thevenon 1908
Maison Thevenon - Editeurs de tissus d'ameublement et Façonneurs de Rideaux et Stores sur mesure depuis 1908
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jjparienti.bsky.social @jjparienti.bsky.social · 03/12/2024
DRIVE OFF-ROAD The perfect participant 01-05 Week-24 Research team very excited to collect plasma HIV-RNA primary endpoint… after paperwork Thank you Manuela 🙏🏼 & Anne for research support!
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Laura Eva, MPH, MS, CPH @lauraeva.bsky.social · 28/11/2024
Mass extinction of cats ensues
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