Reposted by Jim Riley
Meidi Gu, @jimriley52.bsky.social et al. show #CARTcell endocytic activity is lost after continuous tumor engagement exasperating fratricide and CART dysfunction. Rab5 expression restores #endocytosis, thereby improving the potency of CARTs. rupress.org/jem/article/...
#TumorImmunology