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Jessica Little

@jessicalittlemd.bsky.social
1K followers 486 following 4 posts

Transplant Infectious Diseases Physician @ Brigham and Women’s Hospital + Dana-Farber Cancer Institute | Instructor @ Harvard Medical School || heme/onc ID | clinical trials | antimicrobial stewardship ||

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Reposted by Jessica Little
Ilan Schwartz @germhuntermd.bsky.social · 13/04/2026
Candida glabrata emerges as the most common cause of candidemia: analysis of a large hospital-based database, United States, 2016–2024 academic.oup.com/cid/advance-... Jeremy Gold & colleagues at CDC Mycotic Diseases Branch, @jessicalittlemd.bsky.social and @drluiso.bsky.social
Line graph showing the percentage distribution of Candida species from 2016 to 2024.
Candida albicans is the most common species in most years, declining from about 36% to 32%.
Candida glabrata increases overall, rising from about 25% in 2016 to a peak around 34% in 2024.
Candida parapsilosis fluctuates between roughly 8% and 17% before declining to about 8% by
2024. Candida tropicalis and unspecified/other species remain relatively stable at lower levels
(about 6–12%). Multiple-species infections decrease slightly over time. Candida auris is absent
before 2022 and then increases to about 5% by 2023–2024.
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Mycoses Study Group Education & Research Consortium @msgerc.bsky.social · 19/01/2026
New webinar on fungal diagnostics! Link in next post
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Melody Schreiber @melodyschreiber.com · 15/01/2026
BREAKING: The controversial hepatitis B vaccine trial in Guinea-Bissau has been *cancelled,* I can now report. A senior official with Africa CDC confirmed the cancellation and said GB officials are working to make sure any research is conducted ethically: www.theguardian.com/us-news/2026...
theguardian.com
Controversial US study on hepatitis B vaccines in Africa is cancelled
$1.6m project drew outrage over ethical questions about withholding vaccines proven to prevent disease
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BK. Titanji @boghuma.bsky.social · 15/01/2026
The full protocol of the study in Guinea Bissau provides no reassurance. If anything is spells out just how insanely unethical the planned study is. The PI who wrote the protocol tried to defend the indefensible by writing to me directly. I responded publicly. Read 👇 substack.com/@bktitanji/n...
substack.com
BK. Titanji (@bktitanji)
Thank you for taking the time to write such a detailed response. I’m replying directly and point-by-point, because while I appreciate the care with which you’ve articulated your position, I remain fun...
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Luis Ostrosky, MD, FIDSA @drluiso.bsky.social · 14/01/2026
Quick read on #fungal infections in #transplant patients. @jessicalittlemd.bsky.social rocks! #IDSky #MedSky www.contagionlive.com/view/invasiv...
contagionlive.com
Invasive Fungal Disease in Transplantation: Prevention in a Shifting Landscape | Contagion Live
Invasive fungal diseases remain a major cause of morbidity and mortality in patients undergoing transplant, with shifting epidemiology, emerging resistance, and geographic variation underscoring the u...
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Reposted by Jessica Little
Clinical Infectious Diseases @cidjournal.bsky.social · 18/07/2025
Combination Therapy for Protracted COVID-19: When More is More ✅ Just Accepted #IDSky
doi.org
Combination Therapy for Protracted COVID-19: When More is More
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Clinical Infectious Diseases @cidjournal.bsky.social · 19/07/2025
Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy ✅ Just Accepted ⭐ Editor's Choice #IDSky
doi.org
Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy
Immunocompromised patients remain at risk for protracted SARS-CoV-2 infections with persistent viral shedding that could pose a wider public health risk.
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Reposted by Jessica Little
Steven Pergam, MD, MPH @pergamic.bsky.social · 17/06/2025
Important read from all 17 highly qualified ACIP members who recently dismissed - read and share widely jamanetwork.com/journals/jam...
jamanetwork.com
Advisory Committee on Immunization Practices at a Crossroads
In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy, includin...
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Reposted by Jessica Little
Camille Nelson Kotton @kottonnelson.bsky.social · 16/06/2025
Very proud of the 17 ACIP members for publishing this jamanetwork.com/journals/jam...
jamanetwork.com
Advisory Committee on Immunization Practices at a Crossroads
In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy, includin...
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Reposted by Jessica Little
Steven Pergam, MD, MPH @pergamic.bsky.social · 12/06/2025
"The story of the negative impact on the future of infectious disease research will only become part of public discourse if scientists speak up loudly" A must read. One Hundred Days, Incalculable Loses @jidjournal.bsky.social Emily Erbelding, MD - NIAID/DMD academic.oup.com/jid/advance-...
academic.oup.com
One Hundred Days, Incalculable Losses
Emily J Erbelding, M.D., M.P.H; One Hundred Days, Incalculable Losses, The Journal of Infectious Diseases, , jiaf317, https://doi.org/10.1093/infdis/jiaf31
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American Society for Cell Biology @ascbiology.bsky.social · 02/05/2025
Unlawful grant terminations are harming young scientists and threatening innovation. ASCB joins leaders calling for immediate funding restoration. www.ascb.org/society-news...
ascb.org
Leading Life Science Organizations: Unlawful Grant Terminations Pose Grave Threat to America’s Innovation Pipeline - ASCB
Amicus Brief Filed in Support of Suit Calling for Immediate Funding Restoration WASHINGTON, DC – Four leading life science organizations, including the ASCB, filed an amicus brief today asking the cou...
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ASM @asm.org · 02/05/2025
Together with leading science organizations, ASM filed an amicus brief calling for immediate restoration of NIH grants supporting early-career scientists. Read the press release: asm.org/press-releas...
asm.org
Four Leading Science Organizations File Amicus Brief Supporting Funding Restoration
ASM joined leading life science organizations in an amicus brief filed in support of a suit calling for immediate funding restoration.
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Congresswoman Ayanna Pressley @pressley.house.gov · 04/04/2025
🚨UPDATE: Rümeysa Öztürk has now suffered three separate asthma attacks while in DHS custody. She has not received her required asthma medications—a violation of her fundamental right to medical care. This is cruelty, it is neglect, and it is a damning moral and legal failure.
Pressley, Warren, Markey Sound Alarm on Rümeysa Öztürk’s Medical Neglect, Renew Urgent Calls for Her Release (1/2):

“It is unconscionable that Rümeysa Öztürk—a young woman pursuing her education, exercising her First Amendment rights, and contributing to her community—remains detained by DHS. Her ongoing incarceration is not only a blatant violation of her constitutional rights to due process and free speech, but it is now an egregious denial of her fundamental right to medical care. Pressley, Warren, Markey Sound Alarm on Rümeysa Öztürk’s Medical Neglect, Renew Urgent Calls for Her Release (2/2):

“According to her lawyer, Rümeysa has not received her required asthma medications and has now suffered three separate asthma attacks while in custody. This is cruelty, it is neglect, and it is a damning moral and legal failure.

“As her representatives in Congress, we demand DHS immediately provide Rümeysa with access to the health care she needs, and absent compelling evidence justifying her detention and the revocation of her status, we call for Ozturk’s release and the restoration of her visa. Every minute she remains in custody is another minute her health and rights are at risk, and DHS must move with urgency.”
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American Society of Hematology @ash.hematology.org · 01/04/2025
ASH decries HHS restructuring and CDC layoffs. The Blood Disorders Division addresses SCD, thrombosis, hemophilia, thalassemia, and more. Millions' health is at stake; ASH urges immediate action. #Fight4Hematology #HemeSky #MedSky
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Steven Pergam, MD, MPH @pergamic.bsky.social · 01/04/2025
Today our nation's world leadership in science begins a slow death. We lose all the potential innovation, jobs, medicines, novel treatments, & science discoveries to save and improve lives. CDC & NIH will be a shell of themselves. Will hurt for decades. www.splinter.com/bloodbath-at...
splinter.com
'Bloodbath' at NIH and Elsewhere at HHS Begins
Splinter is your home for news and opinions that challenge power in our political and economic system that's becoming more unhinged each and every day.
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Carlos del Río, MD, FACP, FIDSA @docdelrio.bsky.social · 01/04/2025
A sad day for science & public health www.cnn.com/2025/04/01/h...
cnn.com
‘It’s a bloodbath’: Massive wave of job cuts began at US health agencies | CNN
A massive wave of job cuts began at US health agencies early Tuesday, with some employees receiving early morning emails that their jobs were eliminated and some unable to access the building when the...
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Mark Cuban @mcuban.bsky.social · 29/03/2025
Just in NIH grants, It looks like beautiful Iowa City, home of the U of Iowa, will lose $71m in funding. That's almost $1k per resident. And that's before all the other cuts to SSA, FDA, etc. Anyone in Iowa City that can offer more insight? scienceimpacts.org H/T to Prathima !
scienceimpacts.org
SCiMaP
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American Society of Clinical Oncology @ascocancer.bsky.social · 27/03/2025
We are committed to supporting #CancerCare providers and patients who may be affected by public health issues. A listing of measles and vaccination resources can be found on our website and will continue to be updated: asco.org/news-initiat...
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BK. Titanji @boghuma.bsky.social · 27/03/2025
Irresponsible public health leadership is dangerous and it kills. The head of DHHS routinely tries to practice medicine without a license via podcasts and TV interviews and encouraged Vitamin A as treatment for measles. This is the direct result! www.cnn.com/2025/03/26/h....
cnn.com
Some measles patients in West Texas show signs of vitamin A toxicity, doctors say, raising concerns about misinformation | CNN
Doctors treating people hospitalized as part of a measles outbreak in Texas and New Mexico have also found themselves facing another problem: vitamin A toxicity.
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Nate Bahr @natebahrid.bsky.social · 26/03/2025
Sure looks like it'll be a 'study' with a predetermined outcome. If this were really an open question (it is not) it would make sense to contract with one of the numerous centers with extensive experience in vaccine trials. (1/2)
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Joanna Schaenman, MD, PhD @jschaenmanmd.bsky.social · 23/03/2025
We are hiring #TxID #TxIDSky faculty at @ucla-id-fellowship.bsky.social @domucla.bsky.social - come join our dynamic and collaborative group to battle infection in sunny Los Angeles! @ast-idcop.bsky.social See link for description and please reach out with questions! recruit.apo.ucla.edu/JPF09517
recruit.apo.ucla.edu
Clinical Positions in Transplant Infectious Diseases 2024-2025
University of California, Los Angeles is hiring. Apply now!
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Reposted by Jessica Little
Febrile @febrilepodcast.com · 17/03/2025
New episode out now! Get to the bottom of a nonresponding pneumonia and hear some discussions about endemic fungal disease! 🍄 Ft. @tomschmidt30.bsky.social @natebahrid.bsky.social @grthompsonmd.bsky.social Follow @msgerc.bsky.social for more fungal learning! #IDSky
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Jessica Little @jessicalittlemd.bsky.social · 17/03/2025
Loved listening to this new @febrilepodcast.bsky.social episode on endemic mycoses 🍄with @grthompsonmd.bsky.social @tomschmidt30.bsky.social @natebahrid.bsky.social @msgerc.bsky.social febrilepodcast.com/115-dust-to-...
febrilepodcast.com
Febrile #115: Dust to Diagnosis – with MSGERC – febrile
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Tom Schmidt, MD, MHS @tomschmidt30.bsky.social · 17/03/2025
Check out the new episode of @febrilepodcast.bsky.social “Dust to Diagnosis” Great experience working with @grthompsonmd.bsky.social, @natebahrid.bsky.social, & @msgerc.bsky.social! open.spotify.com/episode/61sB... #IDSky #Fungi
open.spotify.com
115: Dust to Diagnosis - with MSGERC
Febrile · Episode
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Ricardo M. La Hoz @ricardolahozmd.bsky.social · 15/03/2025
Looking for a comprehensive review of measles in solid organ transplantation? #TTS #TID organized a webinar that will get your prepared! It is on 🔥 @kottonnelson.bsky.social @jobadd.bsky.social urldefense.com/v3/__https:/...
urldefense.com
20250314-TTS-EC
This is "20250314-TTS-EC" by TTS on Vimeo, the home for high quality videos and the people who love them.
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Stand Up for Science! @standupforscience.net · 13/03/2025
A troubling moment for the next generation of scientists. UMass Chan Med School is rescinding dozens of PhD offers in biomedical sciences due to fears over federal research funding cuts. www.nbcboston.com/news/local/u...
nbcboston.com
UMass Chan rescinds admission for biomedical sciences PhD program amid funding concerns
UMass Chan Medical School is rescinding admission offers to candidates for its biomedical sciences PhD program over concerns about federal funding cuts.
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Miguel Perales MD @drmiguelperales.bsky.social · 10/03/2025
MMR is better than natural infection for many reasons > Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens #measlesoutbreak www.science.org/doi/10.1126/...
science.org
Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens
Measles virus infection can cause long-term damage to the immune system.
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Steven Pergam, MD, MPH @pergamic.bsky.social · 08/03/2025
Why…
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IDSA @idsainfo.bsky.social · 07/03/2025
ID physicians stand up for science to protect our patients. #IDStandsUpForScience In honor of tomorrow's #StandUpForScience rallies, share the reason why you stand up for science with the hashtag #IDStandsUpForScience.
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Luis Ostrosky, MD, FIDSA @drluiso.bsky.social · 04/03/2025
Join us for a webinar on #measles this Friday. Organized by #TEPHI uthealth.zoom.us/webinar/regi...
uthealth.zoom.us
Welcome! You are invited to join a webinar: Measles: A TEPHI Live Forum. After registering, you will receive a confirmation email about joining the webinar.
Join us for "Measles: A TEPHI Live Forum," covering the essentials you need to know about the current measles outbreak, direct from a panel of experts: Luis Ostrosky-Zeichner, MD, physician and infect...
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Mycoses Study Group Education & Research Consortium @msgerc.bsky.social · 03/03/2025
New MSGERC Live Webinar! #Coccidioidomycosis: Clinical Considerations in the Aftermath of #Wildfires What to look for and how to diagnose and treat it March 12 2025, 12-1 pm PT @grthompsonmd.bsky.social and Dr Fariba Donovan FREE Registration: msgerc.wildapricot.org/event-6071071
Flyer for MSGERC Live Webinar, "Coccidioidomycosis: Clinical considerations in the aftermath of wildfires. What to look for and how to diagnose and treat it" featuring Dr George R Thompson III and Dr Fariba Donovan. March 12, 2025, 12-1pm PT. Free registration. www.msgerc.com
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Stand Up for Science! @standupforscience.net · 02/03/2025
WHERE WILL YOU BE ON MARCH 7TH!? Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one! #standupforscience2025
Map of Stand Up for Science events, with official SUFS events in Red and solidarity events in Blue
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CNN @cnn.com · 01/03/2025
Zelensky has thanked the United States on numerous occasions since Russia launched its full-scale invasion in February 2022 – expressing gratitude to Trump and Biden, to members of Congress from both parties, to US defense companies and their employees, and to the American people.
cnn.it
Fact check: 33 times Zelensky thanked Americans and US leaders | CNN Politics
Zelensky has thanked the United States on numerous occasions since Russian launched its full-scale invasion in February 2022 – expressing gratitude to Trump and President Joe Biden, to members of Cong...
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Jessica Little @jessicalittlemd.bsky.social · 28/02/2025
How do wildfires impact the continued rise of Valley Fever 🍄? Come listen to @grthompsonmd.bsky.social and Dr. Fariba Donovan discuss risks, clinical presentation, diagnosis, and treatment in this FREE webinar (March 12, 12-1 PT) hosted by @msgerc.bsky.social msgerc.wildapricot.org/event-6071071
msgerc.wildapricot.org
MSGERC - Coccidioidomycosis: Clinical Considerations in the Aftermath of Wildfires
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Steven Pergam, MD, MPH @pergamic.bsky.social · 28/02/2025
Hugely interesting topic! Definitely tune in #idsky #TxID
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Nate Bahr @natebahrid.bsky.social · 28/02/2025
msgerc.wildapricot.org/event-6071071 Have you heard about Valley Fever occurring after/during the recent California fires? Wondering about how climate change might relate to Cocci? @msgerc.bsky.social has two experts ready to discuss in this FREE webinar. March 12 - will be interesting and useful!
msgerc.wildapricot.org
MSGERC - Coccidioidomycosis: Clinical Considerations in the Aftermath of Wildfires
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Alex Sundermann, DrPH @sundermannaj.bsky.social · 28/02/2025
So now CDC scientists are banned from co-authoring research w/ WHO? Not just new studies - existing ones too This isn’t just bureaucracy. It cuts off global collab on ID, pandemic preparedness, & vaccine research. @altcdc.bsky.social from @mattshuham.bsky.social www.huffpost.com/entry/cdc-wh...
huffpost.com
CDC Staff Prohibited From Co-Authoring Papers With World Health Organization Personnel
It’s just the latest “Orwellian” crackdown on government scientists.
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Chris Murphy @chrismurphyct.bsky.social · 28/02/2025
We are barreling toward a full blown constitutional crisis. Trump's announcement that he's ending thousands of aid contracts FUNDED BY CONGRESS is unconstitutional and illegal - and horrible for our security. 1/ A quick🧵on what's going on. apnews.com/article/trum...
apnews.com
Trump administration says it's cutting 90% of USAID foreign aid contracts
The Supreme Court on Wednesday temporarily blocked a judge’s order giving the Trump administration a midnight deadline to release billions of dollars in U.S. foreign aid.
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Helen Branswell 🇨🇦 @helenbranswell.bsky.social · 28/02/2025
In normal times, I'd have written about this #MMWR report about some of the kids who've died from #flu this year having had a severe neurological condition called influenza-associated encephalopathy or encephalitis. Glad to see @cidrap.bsky.social did write! www.cidrap.umn.edu/influenza-ge...
cidrap.umn.edu
CDC: 13% of kids who died from flu this year had brain damage
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Paul Sax @paulsaxmd.bsky.social · 27/02/2025
If someone thinks the measles outbreak and childhood death in Texas are "not unusual" or "happens all the time", they are deeply misinformed. h/t @adamratnermd.bsky.social for the inspiration. blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org
Tragic Childhood Death from Measles Reminds Us That Some Don't Understand Either the Medical Significance or the Human Heart
My ID colleague Dr. Adam Ratner, Chief of Pediatric ID at NYU Medical Center, just published an insightful and remarkably timely book called Booster Shots:  The Urgent Lessons of Measles and the Uncer...
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Paul Sax @paulsaxmd.bsky.social · 26/02/2025
Repeating myself -- the years of life lost from missed vaccines for life-threatening childhood diseases is vastly higher than for adult preventive measures. Expecting more information later today. Truly tragic. www.nytimes.com/2025/02/26/u...
nytimes.com
Unvaccinated Child Dies of Measles in Texas, Officials Say
At least 124 cases of measles have been identified in Texas since late January, mostly among children and teenagers who are either unvaccinated or whose vaccination status is unknown, officials say.
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Alexandria Ocasio-Cortez @aoc.bsky.social · 22/02/2025
It may not be cool or hip in some circles, but we legitimately do need a massive amount of people to run for office. Flood the school boards, councils, county seats, state legislatures, Congress, etc. Big changes at the top happen when the ground shifts at the bottom. And that can start now.
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Steven Pergam, MD, MPH @pergamic.bsky.social · 21/02/2025
Risk of spread to other states too. With RFK Jr in charge expect more of these events all over the country
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Stand Up for Science! @standupforscience.net · 21/02/2025
The Trump Administration is maintaining the NIH grant freeze despite lawsuits challenging the order, a Nature article reported today. Science funding in the US is already lagging, leaving researchers in limbo. www.nature.com/articles/d41...
nature.com
Revealed: NIH research grants still frozen despite lawsuits challenging Trump order
The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.
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Colorado Clinical and Translational Sciences Institute (CCTSI) @cctsi.bsky.social · 20/02/2025
Colorado joined 21 other states in suing the Trump administration over NIH funding cuts that could devastate medical research. @cuanschutz.bsky.social alone could lose $74 million, jeopardizing public health and access to life-saving medical interventions. @cumedicalschool.bsky.social
buff.ly
Colorado joins lawsuit challenging Trump's NIH cuts that could dismantle state's health research industry
Researchers in Colorado are using words like “catastrophic” and “bombshell” to describe the potential impact of the 15 percent cap.
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Alex Sundermann, DrPH @sundermannaj.bsky.social · 20/02/2025
41/47 (87%) of NIH study sections are cancelled this week Frustrating to see all this good research stalled (& not funded) You can search for study sections that ‘did not meet as scheduled’ here with ones with * ⤵️ www.csr.nih.gov/RevPanelsAnd...
csr.nih.gov
Review Dates
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Dr. Tom Frieden @drtomfrieden.bsky.social · 14/02/2025
Epidemic intelligence service officers are the cream of the cream. They're top doctors, veterinarians & other health professionals. They sign up for a two-year training program to serve the country. Not only is terminating them bad for the country, it's also a disgraceful violation of a commitment.
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lucindasoon @lucindasoon.bsky.social · 12/02/2025
American Bar Association files legal challenge against federal government in USAID funding freeze
americanbar.org
American Bar Association files legal challenge against federal government in USAID funding freeze
CHICAGO, Feb. 12, 2025 — The American Bar Association on Feb. 11 filed a lawsuit with seven co-plaintiffs, a broad array of U.S. Agency for International Development (USAID) and U.S. Department of Sta...
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Judd Legum @juddlegum.bsky.social · 12/02/2025
BREAKING On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.
popular.info
BREAKING: NIH admits funding freeze is illegal, will resume issuing grants
An internal memo issued February 12 was obtained by Popular Information.
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