I'm excited to share the first work from my postdoc in the von Zastrow lab! We address a fundamental question about neuromodulatory signaling: Can neurons tell the difference between multiple neuromodulatory inputs when they converge on only a few receptor pathways? www.biorxiv.org/content/10.6...
biorxiv.org
Temporal coding expands the bandwidth of GPCR-mediated neuromodulation
The advent of modern transcriptomic approaches has revealed a breadth of neuromodulatory G protein-coupled receptor (GPCR) co-expression far exceeding what was previously thought. This raises a fundam...
