Jay Hesselberth @jayhesselberth.bsky.social · 22/02/2026Upset no one told me about Wild Pink. This would have been useful in 2025. 000
Jay Hesselberth @jayhesselberth.bsky.social · 20/06/2025Excited to see this collaborative work with Olivia Rissland's lab finally out. We found lots of 2A peptides and an entirely new 2A class. www.cell.com/cell-reports...cell.comSystematic identification and characterization of eukaryotic and viral 2A peptide-bond-skipping sequencesRao et al. identified thousands of previously unknown 2A peptides across both viruses and eukaryotes using an HMMER analysis. The authors further identified a unique class of 2A peptides, class B, who... 26822
Jay Hesselberth @jayhesselberth.bsky.social · 09/02/2025Just released an update of an R data package for NIH funding data from 1985-2024. github.com/rnabioco/nih...github.comGitHub - rnabioco/nihexporter: An R data package for NIH EXPORTER dataAn R data package for NIH EXPORTER data. Contribute to rnabioco/nihexporter development by creating an account on GitHub. 030
Jay Hesselberth @jayhesselberth.bsky.social · 19/11/2024Here for my first post. Our new approach to study tRNA aminoacylation by nanopore sequencing. Started as a napkin sketch ~1 year ago! This was a fun one, congrats to @laurakwhite.bsky.social and Aleks. www.biorxiv.org/content/10.1...biorxiv.orgNanopore sequencing of intact aminoacylated tRNAsTransfer RNAs (tRNA) are decorated during biogenesis with a variety of modifications that modulate their stability, aminoacylation, and decoding potential during translation. The complex landscape of ... 24712
